Results 71 to 80 of about 5,857 (224)

Brain‐Wide Patterns of CRF Receptor 1 Expression in the Transgenic CRFR1‐Cre‐2a‐tdTom Rat

Journal of Comparative Neurology, Volume 533, Issue 11, November 2025.
In this article, we provide an extensive neuroanatomical characterization of a recently generated CRFR1‐Cre‐2A‐tdTomato rat. We show that Cre and tdTomato are expressed in a pattern that closely aligns with previously reported CRFR1 expression patterns.
Douglas S. Engelke, Lierni Ugartemendia, Jonathan Tao, Shivakumar Rajamanikam, Fabricio H. Do Monte, Nicholas J. Justice   +5 more
wiley   +1 more source

Component of nicotine-induced intracellular calcium elevation mediated through α3- and α5-containing nicotinic acetylcholine receptors are regulated by cyclic AMP in SH-SY 5Y cells.

PLoS ONE, 2020
The pathway from the medial habenular nucleus to the interpeduncular nucleus, in which nicotinic acetylcholine receptor (nAChR) including the α3 and α5 subunits (α3 * and α5 * nAChRs) are expressed, is implicated in nicotine dependence.
Tamayo Takahashi, Takayuki Yoshida, Kana Harada, Tatsuhiko Miyagi, Kouichi Hashimoto, Izumi Hide, Shigeru Tanaka, Masahiro Irifune, Norio Sakai   +8 more
doaj   +1 more source

Ingestion of amniotic fluid enhances the facilitative effect of VTA morphine on the onset of maternal behavior in virgin rats [PDF]

, 2009
Previous research has shown that injection of morphine into the ventral tegmental area(VTA) facilitates the onset of maternal behavior in virgin female rats, and injection of the opioid antagonist naltrexone into the VTA disrupts the onset of maternal ...
Daigler, Lindsey B., Hoey, Robert F., Kristal, Dr. Mark B., Neumann, Anne, Thompson, Dr. Alexis C.   +4 more
core  

Immunocytochemical localization of the neuron-specific form of the c-src gene product, pp60c-src(+), in rat brain [PDF]

, 1990
Neurons express high levels of a variant form of the c-src gene product, denoted pp60c-src(+), which contains a 6 amino acid insert in the amino-terminal half of the c-src protein.
Brugge, J. S., Greengard, P., Gustafson, E. L., Marshak, D. R., Sugrue, M. M.   +4 more
core   +1 more source

STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit

Frontiers in Cellular Neuroscience
IntroductionDiabetes is a metabolic disorder of glucose homeostasis that is a significant risk factor for neurodegenerative diseases, such as Alzheimer’s disease, as well as mood disorders, which often precede neurodegenerative conditions.
Mohammad Jodeiri Farshbaf, Mohammad Jodeiri Farshbaf, Taelor A. Matos, Taelor A. Matos, Kristi Niblo, Kristi Niblo, Yacoub Alokam, Jessica L. Ables, Jessica L. Ables, Jessica L. Ables   +9 more
doaj   +1 more source

Drug-induced Parkinson's disease modulates protein kinase A and Olfactory Marker Protein in the mouse olfactory bulb [PDF]

, 2017
Background Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs.
Caretta, Antonio, Mucignat, Carla
core   +2 more sources

Effect of anticholinergic eye drops on intraorbital, periorbital and brain pulsation power

Acta Ophthalmologica, Volume 103, Issue 7, Page e511-e523, November 2025.
Abstract Purpose The study aims to investigate the effect of pharmacologically reducing parasympathetic activity on ocular and cerebral pulsations, inspired by recent discoveries of a glymphatic‐like system in the eye driven by physiological pulsations.
Seyed Mohsen Ebrahimi, Niko Huotari, Ville Saarela, Marja Honkamo, Lauri Raitamaa, Vesa Korhonen, Johanna Tuunanen, Janne Kananen, Vesa Kiviniemi   +8 more
wiley   +1 more source

Insights into the pathogenesis of nicotine addiction. Could a salivary biosensor be useful in Nicotine Replacement Therapy (NRT)? [PDF]

, 2019
Nicotine has gained the attention of the medical community due to its insidious addictive mechanisms which lead to chronic consumption. The multitude of compounds derived from tobacco smoke have local and systemic negative impacts, resulting in a large ...
Alexescu, Teodora G, Bordea, Roxana, Boșca, Bianca A, Băbțan, Anida-Maria, Câmpian, Radu S, Feurdean, Claudia N, Ilea, Aranka, Ionel, Anca, Miclăuș, Viorel, Mirică, Codruța I, Petrescu, Nausica B, Ruxanda, Flavia, Todea, Adina D, Uriciuc, Willi A   +13 more
core   +2 more sources

Leveraging Fiber Photometry to Decipher Neural Circuits Underlying Anxiety in Mice

Fundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.
ABSTRACT Anxiety disorders rank among the most prevalent mental health conditions worldwide, significantly affecting patients' lives. They are frequently comorbid with other psychiatric disorders, often exacerbating their severity. Current pharmacological treatments; selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines, remain limited in
Salma R. Abdennebi, Nour El Haya Touihri, Emmanuelle Corruble, Denis J. David, Indira Mendez‐David   +4 more
wiley   +1 more source

The medial habenula: still neglected [PDF]

, 2014
The habenula is a small, bilateral brain structure located at the dorsal end of the diencephalon. This structure sends projections to the dopaminergic striatum and receives inputs from the limbic forebrain, making the habenula a unique modulator of cross-
Asasia Q. Carter, David L. Molfese, Humsini Viswanath, Philip R. Baldwin, Ramiro Salas   +4 more
core   +2 more sources