Results 21 to 30 of about 14,963 (141)

Overexpression of BNIP3 in rat intervertebral disk cells triggers autophagy and apoptosis [PDF]

Archives of Biological Sciences, 2022
Excessive apoptosis of intervertebral disk cells and intervertebral disk degeneration (IDD) is the prime cause of low back pain. B-cell lymphoma 2 (Bcl-2) and adenovirus E1B 19 kDa interacting protein 3 (BNIP3), a member of the Bcl-2 family, are involved
Tingsheng Wu, Fan Shaoyong, Zhang Bin, Tao Zhiqiang, Hua Hong, Dai Min   +5 more
doaj   +1 more source

Intervertebral Disk Degeneration and Repair. [PDF]

Neurosurgery, 2018
europepmc   +4 more sources

The Effect and Possible Mechanism of Intradiscal Injection of Simvastatin in the Treatment of Discogenic Pain in Rats

Frontiers in Neuroscience, 2021
To study the effect of intradiscal injection of simvastatin on discogenic pain in rats and its possible mechanism, 30 adult female rats were used in this experiment.
Xiaodong Huang, Xiaodong Huang, Xiaodong Huang, Changkun Zheng, Weiheng Wang, Xiaojian Ye, Chia-Ying Lin, Zenghui Wu   +7 more
doaj   +1 more source

Advanced trends in magnetic resonance imaging in assessment of lumbar intervertebral degenerative disk disease

The Egyptian Journal of Radiology and Nuclear Medicine, 2019
Background T2 mapping and DWI are newly quantitated method for disk degeneration assessment; they were used in the determination of an early stage of intervertebral disk degeneration.
Rania Sobhy Abou Khadrah, Mohamed F. Dawoud, Ashraf Ali Abo-Elsafa, Amr M. Elkilany   +3 more
doaj   +1 more source

Methods and Early Clinical Results of Percutaneous Lumbar Interbody Fusion [PDF]

Neurospine, 2020
Objective Percutaneous lumbar interbody fusion (PELIF) is a procedure that includes the use of new devices, which allow minimally invasive diskectomy under the percutaneous full-endoscopic guidance and safe percutaneous insertion of a standard-sized cage.
Shu Nakamura, Fjio Ito, Zenya Ito, Motohide Shibayama   +3 more
doaj   +1 more source

Correlation among Inflammatory Cytokine Expression Levels, Degree of Disk Degeneration, and Predominant Clinical Symptoms in Patients with Degenerated Intervertebral Discs [PDF]

Asian Spine Journal, 2017
Study DesignObservational study.PurposeTo assess the correlation among inflammatory cytokine expression levels, degree of intervertebral disk (IVD) degeneration, and predominant clinical symptoms observed in degenerative disk disease (DDD).Overview of ...
Takeshi Sainoh, Kazuhide Inage, Sumihisa Orita, Masao Koda, Takeo Furuya, Kazuyo Yamauchi, Miyako Suzuki, Yoshihiro Sakuma, Go Kubota, Yasuhiro Oikawa, Jun Sato, Kazuki Fujimoto, Yasuhiro Shiga, Koki Abe, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Tomotaka Umimura, Kazuhisa Takahashi, Seiji Ohtori   +20 more
doaj   +1 more source

Intervertebral Disk Degeneration and Repair

Neurosurgery, 2017
Abstract Intervertebral disk (IVD) degeneration is a natural progression of the aging process. Degenerative disk disease (DDD) is a pathologic condition associated with IVD that has been associated with chronic back pain. There are a variety of different mechanisms of DDD (genetic, mechanical, exposure).
James, Dowdell, Mark, Erwin, Theodoe, Choma, Alexander, Vaccaro, James, Iatridis, Samuel K, Cho   +5 more
openaire   +3 more sources

The molecular basis of intervertebral disk degeneration

Orthopedic Clinics of North America, 2003
At present, the molecular evidence involved in the degeneration of the IVD is still in its primitive stage. In general, however, intrinsic, extrinsic, and generic factors all have shown a contribution to the initiation of degeneration. These factors may stimulate cytokines and directly or indirectly generate the cellular events thus far detected and ...
Chung, S.A., Khan, S.N., Diwan, Ashish
openaire   +4 more sources

Expression and Distribution of Interleukin-17 in Degenerated Human Cervical Intervertebral Disks

Global Spine Journal, 2012
Introduction To investigate the expression and distribution of interleukin-17 (IL-17) ingenerate human cervical intervertebral disks tissues and to explore the relationship between IL-l7 and cervical intervertebral disk degeneration.
Y. Zhang
doaj   +1 more source

Correlation between MMP-3 Activity and Intervertebral Disk Degeneration According to Radiologic Data

Global Spine Journal, 2012
Introduction During the degeneration process, tissue resorption causes a progressive and important decrease in intervertebral disk height. The main characteristics of disk degeneration are intradiscal clefts and teardrops.
S. Canbay, S. caglar, N. turhan, K. Arda
doaj   +1 more source