Results 21 to 30 of about 258,180 (266)
Establishing the intracellular niche of obligate intracellular vacuolar pathogens
Frontiers in Cellular and Infection Microbiology, 2023 Obligate intracellular pathogens occupy one of two niches – free in the host cell cytoplasm or confined in a membrane-bound vacuole. Pathogens occupying membrane-bound vacuoles are sequestered from the innate immune system and have an extra layer of protection from antimicrobial drugs. However, this lifestyle presents several challenges.
Tatiana M. Clemente +2 more
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Frontiers in Cellular and Infection Microbiology, 2021 The facultative intracellular pathogen Salmonella enterica Typhimurium (STM) resides in a specific membrane-bound compartment termed the Salmonella-containing vacuole (SCV).
Jennifer Röder +3 more
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Cross-regulation in a three-component cell envelope stress signaling system of Brucella
mBio, 2023 A multi-layered structure known as the cell envelope separates the controlled interior of bacterial cells from a fluctuating physical and chemical environment.
Xingru Chen +3 more
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Definition of intracellular pathogens [PDF]
Clinical Microbiology and Infection, 1996 Most microorganisms are destroyed by the host tissues through processes which usually involve phagocytosis and lysosomal disruption. However, some organisms are capable of growing inside macrophages and avoiding destruction. This paper describes the normal phagocytic process and how it is avoided by certain viruses, bacteria and protozoa, and the ...
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Frontiers in Cellular and Infection Microbiology, 2018 Burkholderia pseudomallei and B. mallei are the causative agents of melioidosis and glanders, respectively, and are often fatal to humans and animals. Owing to the high fatality rate, potential for spread by aerosolization, and the lack of efficacious ...
Magdalena Franco +6 more
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Cryptococcal pathogenic mechanisms: a dangerous trip from the environment to the brain
Memorias do Instituto Oswaldo Cruz, 2018 Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious infections, most commonly of the central nervous system (CNS). C. neoformans is mainly found in the environment and acquired by inhalation.
Shannon K Esher +2 more
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Study on the Occurrence of Genetic Exchange Among Parasites of the Leishmania mexicana Complex
Frontiers in Cellular and Infection Microbiology, 2020 In Leishmania, genetic exchange has been experimentally demonstrated to occur in the sand fly vector and in promastigote axenic cultures through a meiotic-like process.
Roman Telittchenko, Albert Descoteaux
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Apoptosis assessment in high-content and high-throughput screening assays
BioTechniques, 2021 Here the authors describe the development of AUTOptosis, an economical and rapid apoptosis monitoring method suitable for high-content and high-throughput screening assays.
Céline Rens +5 more
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Intracellular innate resistance to bacterial pathogens [PDF]
Cellular Microbiology, 2006 Mammalian innate immunity stimulates antigen-specific immune responses and acts to control infection prior to the onset of adaptive immunity. Some bacterial pathogens replicate within the host cell and are therefore sheltered from some protective aspects of innate immunity such as complement.
Radtke, Andrea Lynn +1 more
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Antibiotics, 2019 Neutrophils are important assets in defense against invading bacteria like staphylococci. However, (dysfunctioning) neutrophils can also serve as reservoir for pathogens that are able to survive inside the cellular environment. Staphylococcus aureus is a
Suzanne Bongers +4 more
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