Results 1 to 10 of about 803,683 (201)
Intracellular cholesterol transport
Journal of Lipid Research, 1997 Recent data on the roles of vesicle- and ‘raft‘-mediated pathways in intracellular free cholesterol (FC) transport are reviewed. Cholesterol internalized from plasma lipoproteins is transferred via endocytic vesicles to the trans-Golgi network (TGN ...
C J Fielding, P E Fielding
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Intracellular Transport in Cancer Metabolic Reprogramming [PDF]
Frontiers in Cell and Developmental Biology, 2020 Tumor progression is a complex process consisting of several steps characterized by alterations in cellular behavior and morphology. These steps include uncontrolled cell division and proliferation, invasiveness and metastatic ability.
Marte Sneeggen +2 more
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Molecular Motors Orchestrate Pause-and-Run Dynamics to Facilitate Intracellular Transport [PDF]
BiomoleculesIntracellular transport is essential for cellular organization and function. This process is driven by molecular motors that ferry cargo along microtubules, but is characterized by intermittent motility, where cargoes switch between directed runs and ...
Yusheng Shen, Kassandra M. Ori-McKenney
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Intracellular Cholesterol Synthesis and Transport
Frontiers in Cell and Developmental Biology, 2022 Cholesterol homeostasis is related to multiple diseases in humans, including cardiovascular disease, cancer, and neurodegenerative and hepatic diseases.
Qingyang Shi +4 more
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Intracellular cholesterol transport.
Journal of Lipid Research, 1992 The intracellular movement of cholesterol in mammalian cells may involve complex pathways by which the sterol moves to various cellular sites and mediates transcriptional regulation, enzyme activation, and protein degradation.
L Liscum, NK Dahl
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Myosin-Driven Intracellular Transport. [PDF]
Cold Spring Harb Perspect Biol, 2018 The delivery of intracellular material within cells is crucial for maintaining normal function. Myosins transport a wide variety of cargo, ranging from vesicles to ribonuclear protein particles (RNPs), in plants, fungi, and metazoa. The properties of a given myosin transporter are adapted to move on different actin filament tracks, either on the ...
Titus MA.
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Heterogeneities Shape Passive Intracellular Transport. [PDF]
Biophys J, 2019 A living cell's interior is one of the most complex and intrinsically dynamic systems, providing an elaborate interplay between cytosolic crowding and ATP-driven motion, which controls cellular functionality. Here, we investigated two distinct fundamental features of the merely passive, not-bio-motor shuttled material transport within the cytoplasm of ...
Witzel P +5 more
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Mouse Syngeneic Melanoma Model with Human Epidermal Growth Factor Receptor Expression
Pharmaceutics, 2022 The development of epidermal growth factor receptor (EGFR)-targeting agents for the treatment of malignant melanoma requires cheap and easy animal tumor models for high-throughput in vivo screening.
Tatiana A. Slastnikova +6 more
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Monovalent ions and stress-induced senescence in human mesenchymal endometrial stem/stromal cells
Scientific Reports, 2022 Monovalent ions are involved in growth, proliferation, differentiation of cells as well as in their death. This work concerns the ion homeostasis during senescence induction in human mesenchymal endometrium stem/stromal cells (hMESCs): hMESCs subjected ...
Alla Shatrova +5 more
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Modular Nanotransporters Delivering Biologically Active Molecules to the Surface of Mitochondria
Pharmaceutics, 2023 Treatment of various diseases, in particular cancer, usually requires the targeting of biologically active molecules at a selected subcellular compartment.
Yuri V. Khramtsov +6 more
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