Results 61 to 70 of about 32,558 (212)

Prelacrimal Transmaxillary‐Orbital Approach for Resection of Lateral Extraconal Orbital Cavernous Hemangioma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Endoscopic orbital surgery is likely a reasonable option for patients with orbital cavernous hemangiomas (OCH) medial to the optic nerve (ON). The endoscopic resection of OCH lateral to the ON is extremely challenging. Zhou et al. first described the endoscopic prelacrimal recess approach (PLRA) for the management of the maxillary sinus and ...
Zhen‐Xiao Huang, Xiao‐Qing Zhang, Bing Zhou   +2 more
wiley   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy, Lei Cheng, De‐Yun Wang   +2 more
wiley   +1 more source

Personalized Surgery for Allergic Fungal Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Allergic fungal rhinosinusitis (AFRS) frequently presents as unilateral or asymmetric disease. In cases with minimal disease on one side, the question remains as to the necessary extent of surgery. Objective To determine the relationship between symmetry and clinical characteristics in AFRS patients, with a focus on implications for
Erin E. Briggs, Zachary M. Soler, Asher T. Ripp, Ryan A. Durgham, Shabih H. Jafri, Alexander N. Duffy, Vinay K. Rathi, Rodney J. Schlosser   +7 more
wiley   +1 more source

ChatGPT Versus DeepSeek in Resectability Categorization of Chronic Rhinosinusitis: A Comparison Based on EPOS 2020

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate and compare the performance of ChatGPT‐5.5 (2026) and DeepSeek‐V3 (2026) in classifying CRS resectability according to the EPOS 2020 guidelines, employing various prompting strategies. Methods In this retrospective study, 150 chronic rhinosinusitis cases were reviewed, and three rhinology experts classified resectability ...
Jia‐Hong Lao, Shu‐Yi Huang, Fei‐Tong Jian, Rong‐Rong Ge, Yu Jiang, Xue‐Kun Huang, Zhao‐Hui Shi, Qin‐Tai Yang, Shuo Wu   +8 more
wiley   +1 more source

Turbinoplasty Versus Medical Treatment for Allergic Rhinitis: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Allergic rhinitis is a common chronic condition affecting up to 30% of adults worldwide, with nasal obstruction being the most bothersome symptom. Inferior turbinate hypertrophy is a major contributor to nasal obstruction in allergic rhinitis, and surgical reduction techniques have been developed for cases refractory to medical ...
Noof Albannai, Hajar Alismail, Abdullah N. Aladwani, Abdur Rehman, Abdullah AlShuaib, Retaj Alawadhi, Jassim AlMusaileem, Meshal T. Alshammari, Omar Bader Alharbi, Bader A. Alasoosi, Sarah S. Alenezi, Abdullah M. Alharran, Ebraheem Albazee   +12 more
wiley   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Autonomous intranasal delivery systems for central nervous system therapeutics. [PDF]

Exp Mol Med
Shen H, Srivastava SK, Aggarwal N, Chang MW.   +3 more
europepmc   +1 more source

Intranasal drug delivery: a novel approach [PDF]

Indian Journal of Otolaryngology and Head & Neck Surgery, 2009
Yashpal, Chugh, Pragati, Kapoor, A K, Kapoor   +2 more
openaire   +2 more sources

Psychological change processes in alcohol use disorder: A qualitative study of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) with cognitive behavioural therapy

Addiction, EarlyView.
Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, James J. Rucker, Anthony Cleare, John Marsden   +6 more
wiley   +1 more source

Intranasal Delivery of Gallium-Quercetin Nanoparticles for Multi-Target Ferroptosis Inhibition in Parkinson's Disease. [PDF]

Adv Sci (Weinh)
Xu K, Kou D, Xiao X, Bai B, Liu C, Wu M, Shi Y, Xu M, Cao X, Qi H, Wu S, Zeng J, Gao M.   +12 more
europepmc   +1 more source