Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg +18 more
wiley +1 more source
Intranasal delivery of cerium oxide nanozyme and superoxide dismutase in exosomes for Parkinson's disease therapy. [PDF]
Shao X +6 more
europepmc +1 more source
Both Full and Limited FESS result in clinically meaningful relief of disease‐specific HRQoL and nasal breathing, effectively improving nasal symptoms and sleep disturbance in CRSwNP patients. Clinically meaningful difference in decrease of SNOT‐22 scores between the groups was not found at 12‐ and 24–month follow‐up.
P. Virkkula +10 more
wiley +1 more source
Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations
Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal +42 more
wiley +1 more source
Development and Optimization of an Eplerenone-Loaded Liposomal In Situ Gel for Enhanced Intranasal Delivery. [PDF]
Baranauskaite J +5 more
europepmc +1 more source
Intranasal Delivery of Bacterial Extracellular Vesicles Enables RNA Cargo Entry Into the Brain. [PDF]
Ha JY +8 more
europepmc +1 more source
Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz +22 more
wiley +1 more source
ROS-responsive nanoplatform-mediated targeted intranasal delivery of Piezo2 siRNA for the treatment of trigeminal neuralgia. [PDF]
Wang Y +12 more
europepmc +1 more source
The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith +9 more
wiley +1 more source
Development and Optimization of 7,8-Dihydroxyflavone-Loaded Polylysine/Lecithin Nanoparticles for Potential Intranasal Delivery. [PDF]
Salamone S +7 more
europepmc +1 more source

