Results 1 to 10 of about 158,913 (343)

Retained Lumbar Drain Tip Leading to Intrathecal Hematoma: A Case Report on Perioperative Risks and Management. [PDF]

Cureus
Lee SJ, Gattu K, Sappenfield JW.
europepmc   +3 more sources

Efficacy and safety of intrathecal morphine for analgesia after lower joint arthroplasty: a systematic review and meta‐analysis with meta‐regression and trial sequential analysis

Anaesthesia, 2021
Widespread adoption of intrathecal morphine into clinical practice is hampered by concerns about its potential side‐effects. We undertook a systematic review, meta‐analysis and trial sequential analysis with the primary objective of determining the ...
E. Gonvers, K. El-Boghdadly, S. Grape, E. Albrecht   +3 more
semanticscholar   +1 more source

Intrathecal Antibacterial and Antifungal Therapies

Clinical Microbiology Reviews, 2020
Intrathecal administration of anti-infectives is indicated in central nervous system infections by multiresistant pathogens when drugs that can reach adequate cerebrospinal fluid (CSF) concentrations by systemic therapy are not available.
R. Nau, C. Blei, H. Eiffert
semanticscholar   +1 more source

Efficacy of Intrathecal Fentanyl for Cesarean Delivery: A Systematic Review and Meta-analysis of Randomized Controlled Trials With Trial Sequential Analysis.

Anesthesia and Analgesia, 2020
BACKGROUND Fentanyl and morphine are the 2 most commonly added opioids to bupivacaine for spinal anesthesia during cesarean delivery. Numerous clinical trials have assessed efficacy and safety of different doses of fentanyl added to intrathecal ...
V. Uppal, S. Retter, M. Casey, S. Sancheti, K. Matheson, D. McKeen   +5 more
semanticscholar   +1 more source

Off-label intrathecal use of gadobutrol: safety study and comparison of administration protocols

Neuroradiology, 2020
Purpose Magnetic resonance imaging (MRI) contrast agents have been used off-label for diagnosis of cerebrospinal fluid (CSF) leaks and lately also for assessment of the glymphatic system and meningeal lymphatic drainage.
M. Halvorsen, C. Edeklev, J. Fraser-Green, Grethe Løvland, S. Vatnehol, Ø. Gjertsen, B. Nedregaard, Ruth O. Sletteberg, G. Ringstad, P. Eide   +9 more
semanticscholar   +1 more source

Intrathecal Morphine versus Intrathecal Hydromorphone for Analgesia after Cesarean Delivery

Anesthesiology, 2020
Background: Intrathecal opioids are routinely administered during spinal anesthesia for postcesarean analgesia. The effectiveness of intrathecal morphine for postcesarean analgesia is well established, and the use of intrathecal hydromorphone is growing.
E. Sharpe, R. Molitor, K. Arendt, V. E. Torbenson, D. Olsen, Rebecca Lynn Johnson, D. Schroeder, A. Jacob, Adam D. Niesen, H. Sviggum   +9 more
semanticscholar   +1 more source

BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates [PDF]

, 2019
© 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Background: The marked increase in mis-use of prescription opioids has greatly affected our society. One potential solution is to develop improved analgesics which have
Cami-Kobeci, Gerta, Czoty, Paul W., DeLoid, Heather B., Ding, Huiping, Hsu, Fang Chi, Husbands, Stephen M., Kiguchi, Norikazu, Ko, Mei Chuan, Sukhtankar, Devki D., Toll, Lawrence   +9 more
core   +5 more sources

Mas-related G-protein–coupled receptors inhibit pathological pain in mice [PDF]

, 2010
An important objective of pain research is to identify novel drug targets for the treatment of pathological persistent pain states, such as inflammatory and neuropathic pain.
Altier, Baron, Basbaum, Cai, Calignano, Callaghan, Caterina, Chen, Chen, Coderre, Costigan, Costigan, D. J. Anderson, De Felipe, Delmas, Dong, Gerevich, Guan, Guan, Herrero, Honan, Ikeda, Julius, Knabl, Kusudo, Lembo, Li, Li, Liu, Liu, Lu, MacDermott, MacPherson, Malmberg, Melzack, Melzack, Miraucourt, Ndong, Neumann, Q. Liu, Rau, Rodriguez Parkitna, S. N. Raja, Scholz, Seal, Woolf, X. Dong, Y. Guan, Z. Tang, Zeng   +49 more
core   +2 more sources

Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]

, 2003
Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
core   +1 more source

Inflammatory intrathecal profiles and cortical damage in multiple sclerosis

Annals of Neurology, 2018
Gray matter (GM) damage and meningeal inflammation have been associated with early disease onset and a more aggressive disease course in multiple sclerosis (MS), but can these changes be identified in the patient early in the disease course?
R. Magliozzi, O. Howell, R. Nicholas, C. Cruciani, M. Castellaro, C. Romualdi, S. Rossi, Marco Pitteri, M. Benedetti, A. Gajofatto, F. Pizzini, S. Montemezzi, S. Rasia, R. Capra, A. Bertoldo, F. Facchiano, S. Monaco, R. Reynolds, M. Calabrese   +18 more
semanticscholar   +1 more source