Results 31 to 40 of about 74,181 (306)

Intrathecal Pumps [PDF]

Neurotherapeutics, 2008
Direct neuroaxis drug delivery has expanded the physician's armamentarium to provide treatment options to those who have failed more conservative interventions. Starting from Bier's 'cocainization of the spinal cord' in 1898, direct nervous system pharmacy delivery has long been recognized as an effective means to treat pain.
Shawn, Belverud, Alon, Mogilner, Michael, Schulder   +2 more
openaire   +2 more sources

Preoperative topical intranasal fluorescein in diagnosis of cerebrospinal fluid rhinorrhea

Archives of Trauma Research, 2018
Background and Objectives: The preoperative diagnosis of cerebrospinal fluid (CSF) leak site is necessary for the management of CSF rhinorrhea. At present, intrathecal fluorescein is a common approach for it; however, regarding drawbacks, its value is ...
Seyed Mostafa Hashemi Jazi, Zhale Amini, Masih Saboori, Mostafa Raisi   +3 more
doaj   +1 more source

The effects of Adding Meperidine to Heavy Intrathecal Lidocaine on Hemodynamic Changes and Blood Loss in Open Prostatectomy: A Randomized Double-Blind Clinical Trial [PDF]

Iranian Journal of Medical Sciences, 2012
Background: Clinical investigations have reported several anesthetic properties of intrathecal injections of meperidine. The purpose of this study was to investigate the effect of adding meperidine to intrathecal heavy lidocaine on hemodynamic changes ...
Abdolreza Najafi Anaraki, Mohamadzaki Abbasi, Abdolrasoul Anvarypour, Niloofar Motamed   +3 more
doaj  

A prospective, double-blind dose-ranging study of intrathecal nalbuphine in the lower abdominal and lower limb surgeries

Indian Journal of Pain, 2016
Background: Nalbuphine is a synthetic opioid with mixed agonist-antagonist action, used as an adjuvant with intrathecal bupivacaine to prolong postoperative analgesia.
Sandip Roy Basunia, Suman Chattopadhyay, Aditi Das, Baishaki Laha, Debasish Bhar, Rita Pal   +5 more
doaj   +1 more source

Intrathecal injection of bone marrow concentrate in children with autism spectrum disorder: a retrospective chart analysis

Frontiers in Medicine
BackgroundThe growing prevalence of autism spectrum disorder (ASD) underscores the urgent need for therapies that target underlying biological mechanisms, with cell-based interventions offering a potentially transformative approach by targeting core ...
Georg S. Kobinia, Georg S. Kobinia, Adam Bukaty, Elisabeth Holly, Gloria Kobinia, Gloria Kobinia, Philipp R. Heuberer, Philipp R. Heuberer, Brenda Laky, Brenda Laky, Brenda Laky, Brenda Laky   +11 more
doaj   +1 more source

Comparison of nalbuphine versus fentanyl as intrathecal adjuvant to bupivacaine for orthopedic surgeries: A randomized controlled double-blind trial

Journal of Anaesthesiology Clinical Pharmacology, 2021
Background and Aims: Intrathecal adjuvants are used with local anesthetics to prolong the duration and provide postoperative pain relief while minimizing the dose of local anesthetic.
Ankit Sharma, Sujata Chaudhary, Mahendra Kumar, Ruchi Kapoor   +3 more
doaj   +1 more source

Patient intrathecal pain pump safety [PDF]

, 2022
Background: A large tertiary care hospital in the Midwest manages care for approximately 200 patients with implanted intrathecal pain pumps. Nurses perform the high-risk task of refilling these pumps with highly concentrated medications. An inherent risk,
Loppnow, Tracy
core   +3 more sources

Decompression for lumbar spinal stenosis at the intrathecal catheter insertion site during intrathecal baclofen therapy: a case report

, 2023
Background Intrathecal baclofen therapy can substantially improve symptoms in most patients with severe spasticity due to traumatic spinal cord injury, multiple sclerosis, or cerebral paresis.
Hidehumi Ebara, Aki Nakanami, Kenji Kagechika, Yoshiyuki Kitano, Hiroyuki Hayashi, Kazu Toyooka, Akari Mori, Tetsutaro Yahata, Hiroshi Yamada, Hiroyuki Tsuchiya, Hiroyuki Inatani, Yasutaka Takagi   +11 more
core   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Improved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery

Molecular Therapy: Methods & Clinical Development, 2017
Intravenous administration of adeno-associated virus serotype 9 (AAV9)/hMECP2 has been shown to extend the lifespan of Mecp2−/y mice, but this delivery route induces liver toxicity in wild-type (WT) mice.
Sarah E. Sinnett, Ralph D. Hector, Kamal K.E. Gadalla, Clifford Heindel, Daphne Chen, Violeta Zaric, Mark E.S. Bailey, Stuart R. Cobb, Steven J. Gray   +8 more
doaj   +1 more source