Results 51 to 60 of about 74,181 (306)

Intrathecal Drug Delivery for Pain

open access: yes, 2022
This chapter discusses the important role of intrathecal drug delivery for the treatment of chronic cancer and non-cancer pain. Specific diagnostic considerations and the role of an intrathecal trial for appropriate patient selection are discussed in ...
Sukul, Vishad V   +2 more
core   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal   +10 more
wiley   +1 more source

Intrathecal Pumps

open access: yes, 2018
Neuromodulation options that exist for chronic pain treatment include targeted intrathecal drug delivery, spinal cord stimulation, deep brain stimulation, cortical stimulation, and peripheral field stimulation. This chapter focuses on the neuromodulation
Richard L. Boortz-Marx   +2 more
core   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong   +10 more
wiley   +1 more source

Effect of intrathecal labor analgesia using fentanyl 25 μg and bupivacaine 2.5 mg on progress of labor

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2017
Background: The aim of this study was to evaluate the progress of labor and hemodynamic changes in the mother and fetus with intrathecal analgesia using bupivacaine and fentanyl during normal vaginal delivery.
Pooja Mathur   +5 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Intrathecal dexmedetomidine as adjuvant for spinal anaesthesia for perianal ambulatory surgeries: A randomised double-blind controlled study

open access: yesIndian Journal of Anaesthesia, 2015
Background and Aim: The newer trend in regional anaesthesia for ambulatory anorectal surgeries advocate use of lower dose of local anaesthetic, providing segmental block with adjuvants such as opioids and α2 agonists to prolong analgesia.
S S Nethra   +5 more
doaj   +1 more source

Intrathecal Fentanyl for Labour Analgesia in a Patient with Severe Mitral Stenosis and Atrial Fibrillation in Advanced Stage of Labour-Case Report [PDF]

open access: yes, 2013
Labour is an intensely painful experience and puts considerable physiological stress on the circulation. A case of rheumatic valvular heart disease with severe mitral stenosis in atrial fibrillation is discussed here in which analgesia with intrathecal ...
Vaijayanti Nitin Gadre
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

The effect of different intrathecal doses of meperidine on shivering during delivery under spinal anesthesia

open access: yesInternational Journal of Preventive Medicine, 2012
Background: This study was performed to compare the effect of different doses of intrathecal meperidine on the incidence and intensity of shivering and other side-effects after spinal anesthesia for cesarean delivery.
Abdolreza Najafi Anaraki, Kamran Mirzaei
doaj  

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