Results 121 to 130 of about 74,181 (306)

Intrathecal pain pump causing delayed acute flaccid paralysis: A case report and review of the literature

Clinical Case Reports
Key Clinical Message Patients with intrathecal catheters for pain medication infusion should be aware of the possible complication of acute flaccid paralysis.
Megan Finneran, Emilio Nardone
doaj   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, EarlyView.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source

Survey of pain specialists regarding conversion of high-dose intravenous to neuraxial opioids

Journal of Pain Research, 2016
Andrew W Gorlin, David M Rosenfeld, Jillian Maloney, Christopher S Wie, Johnathan McGarvey, Terrence L Trentman Department of Anesthesiology, Mayo Clinic Arizona, Phoenix, AZ, USA Abstract: The conversion of high-dose intravenous
Gorlin AW, Rosenfeld DM, Maloney J, Wie CS, McGarvey J, Trentman TL   +5 more
doaj  

A prospective randomized controlled double blinded interventional study to compare post operative analgesia using sequential intrathecal injection of fentanyl at different rates with hyperbaric bupivacaine in lower segment caesarean sections

Journal of Obstetric Anaesthesia and Critical Care
Background: This study compared rapid and slow intrathecal fentanyl injection followed by a slow injection of bupivacaine to estimate the duration of postoperative analgesia in lower-segment caesarean sections (LSCS).
Nelwin J Sabu, Harpreet Kaur, Veena Shukla, Harsh K Harsh, Ravi Pareek, Ekta Rani   +5 more
doaj   +1 more source

The Addition of Intrathecal Clonidine to Reduce Medication-Related Side-Effects in Cancer Pain: A Retrospective Cohort Study [PDF]

Evgeny Bulat,1 Rahul Chaturvedi,2 Peyton Johnson,2 Neal Rakesh,3 Amitabh Gulati3 1Pain Treatment Specialists, VIP Medical Group, New York, NY, USA; 2Department of Anesthesiology, NewYork-Presbyterian/Weill Cornell Medical Center, New York, NY, USA ...
Bulat E, Rakesh N, Johnson P, Chaturvedi R, Gulati A   +4 more
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Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

EFFECTS OF INTRATHECAL BUPIVACAINE WITH NORMAL SALINE VERSUS BUPIVACAINE WITH FENTANYL IN PATIENTS UNDERGOING SURGERY

National Journal of Medical Research, 2016
Objective:To know the effects of intrathecal 0.5% Bupivacaine 2.5 cc with 0.5 cc normal saline and 0.5% Bupivacaine 2.5 cc witth 25 μg fentanyl for various lower abdominal surgeries. Methods: A comparative study were conducted in 60 (ASA grade I / II)
Jigna R Shah, Manish Bhatt
doaj  

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Intrathecal Morphine for Neuropathic Pain in a Pregnant Cancer Patient

, 2008
Although they have been documented, opioid treatments in obstetrics are mostly limited to methadone maintenance treatment in pregnant addicts or analgesia/anesthesia for labor.
溫永銳;侯文詠;陳育安;謝長堯;孫維仁, WEN, YEONG-RAY;HOU, WEN-YEONG;CHEN, YU- AN;HSIEH, CHANG-YAO;SUN, WEI-ZEN   +1 more
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