Results 121 to 130 of about 76,887 (294)

Survey of pain specialists regarding conversion of high-dose intravenous to neuraxial opioids

Journal of Pain Research, 2016
Andrew W Gorlin, David M Rosenfeld, Jillian Maloney, Christopher S Wie, Johnathan McGarvey, Terrence L Trentman Department of Anesthesiology, Mayo Clinic Arizona, Phoenix, AZ, USA Abstract: The conversion of high-dose intravenous
Gorlin AW, Rosenfeld DM, Maloney J, Wie CS, McGarvey J, Trentman TL   +5 more
doaj  

A prospective randomized controlled double blinded interventional study to compare post operative analgesia using sequential intrathecal injection of fentanyl at different rates with hyperbaric bupivacaine in lower segment caesarean sections

Journal of Obstetric Anaesthesia and Critical Care
Background: This study compared rapid and slow intrathecal fentanyl injection followed by a slow injection of bupivacaine to estimate the duration of postoperative analgesia in lower-segment caesarean sections (LSCS).
Nelwin J Sabu, Harpreet Kaur, Veena Shukla, Harsh K Harsh, Ravi Pareek, Ekta Rani   +5 more
doaj   +1 more source

Intrathecal noradrenaline restores 5-methoxy-N,N-dimethyltryptamine induced antinociception abolished by intrathecal 6-hydroxydopamine

, 1988
Intrathecal administration of 6-hydroxydopamine (6-OHDA) abolished the antinociceptive effects of acute administration of 5-methoxy-N,N-dimethyltryptamine (5-MeODMT, 1 mg/kg, s.c.) in the hot-plate, tail-flick and shock titration tests of nociception ...
Persson, ML, Archer, T, Post, C, Jonsson, G, Minor, BG   +4 more
core   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik, Suyeon Son, Jaesung Lee, Ki Soo Park   +3 more
wiley   +1 more source

EFFECTS OF INTRATHECAL BUPIVACAINE WITH NORMAL SALINE VERSUS BUPIVACAINE WITH FENTANYL IN PATIENTS UNDERGOING SURGERY

National Journal of Medical Research, 2016
Objective:To know the effects of intrathecal 0.5% Bupivacaine 2.5 cc with 0.5 cc normal saline and 0.5% Bupivacaine 2.5 cc witth 25 μg fentanyl for various lower abdominal surgeries. Methods: A comparative study were conducted in 60 (ASA grade I / II)
Jigna R Shah, Manish Bhatt
doaj  

Seizure improvement following intravenous immunoglobulin in drug‐resistant mesial temporal lobe epilepsy associated with systemic lupus erythematosus

Epileptic Disorders, EarlyView.
Kristijonas Puteikis, Basma Marzouk, Fabrice Bartolomei, Stanislas Lagarde   +3 more
wiley   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Aspergillus arachnoiditis post intrathecal baclofen pump insertion

, 2013
This report describes an unusual fungal infection of an intrathecal baclofen pump which, to our knowledge, has not been reported previously. We describe a 39-year-old man with severe lower limb spasticity due to secondary progressive multiple sclerosis ...
Butzkueven, H., Hogg, M., Eisen, D.P., Vivek, V., Kavar, B.   +4 more
core   +1 more source

Pharmaco‐resistant focal epilepsy of undetermined origin responding to corticosteroids: A clinical vignette

Epileptic Disorders, EarlyView.
Félicien Gautier, Patrice H. Lalive, Pierre Mégevand   +2 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source