Results 101 to 110 of about 74,181 (306)

Intrathecal/Intraventricular Linezolid in Multidrug-Resistant Enterococcus faecalis Ventriculitis

Journal of Neurological Surgery Reports, 2016
Background The use of intrathecal antibiotic therapy for the treatment of ventriculitis and/or meningitis has demonstrated efficacy especially when sterilization of the cerebrospinal fluid is not possible with intravenous antibiotics alone ...
Brian F. Lich, Andrew K. Conner, Joshua D. Burks, Chad A. Glenn, Michael E. Sughrue   +4 more
doaj   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Intrathecal Therapy in Cancer Pain Management [PDF]

, 2006
The lack of knowledge of intrathecal therapy in cancer pain management by nurses and other health care professionals is a common problem that creates poor patient satisfaction and decreased quality of life. Intrathecal pain pumps may be helpful in cancer
Nygaard, Anne
core   +1 more source

Effect of delayed intrathecal administration of capsaicin on neuropathic pain induced by chronic constriction injury of the sciatic nerve in rats

, 2014
Kun Zhang,1 Somayaji Ramamurthy,1 Thomas J Prihoda,2 Maxim S Eckmann1 1Department of Anesthesiology, 2Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA Purpose: The current study was designed to ...
Zhang K, Ramamurthy S, Eckmann MS, Prihoda TJ   +3 more
core  

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Efficacy and safety of cannabinoids in the treatment of spasticity in multiple sclerosis: A systematic review of randomized clinical trials

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to evaluate the efficacy and safety of cannabinoids for the treatment of MS‐related spasticity. Methods Systematic searches were conducted in PubMed, EMBASE, and LILACS on 2 December 2025. Randomized controlled trials evaluating natural or synthetic cannabinoids for MS‐related spasticity were included.
Letícia Hamm‐Buiar, Daniela Gorski, Marcela Harumi Kagueiama, Astrid Wiens   +3 more
wiley   +1 more source

Intrathecal Migration of Epidural Catheter

, 2021
Epidural catheters that are placed for anaesthesia or analgesia have a serious complication of migration. Migrations can be intravascular, subdural, or intrathecal.
Dakhlallah, Nadeen, Bazzy, Yusef, Moussa, Adib R, Cruz, Adam J   +3 more
core   +1 more source

Management of spasticity with intrathecal phenol injections: The past and the present

The Journal of the International Society of Physical and Rehabilitation Medicine, 2019
Introduction: Spasticity is increased, involuntary, velocity-dependent muscle tone that causes resistance to movement. Intrathecal injection of phenol is a form of treatment used in a very selective group of patients with spasticity. Aim: This study aims
Fahim Anwar, Silvia Antiga, Harry Mee, Ahmad Al Khayer   +3 more
doaj   +1 more source

Biodistribution of Idursulfase Formulated for Intrathecal Use (Idursulfase-IT) in Cynomolgus Monkeys after Intrathecal Lumbar Administration. [PDF]

, 2016
Enzyme replacement therapy with intravenous idursulfase (recombinant iduronate-2-sulfatase) is approved for the treatment of Hunter syndrome. Intravenous administration does not, however, treat the neurological manifestations, due to its low central ...
Eilish Brown, Bob Crooker (3232881), Kathleen J. Palmieri (3232884), Kathleen J Palmieri, Thomas G McCauley, Thomas G. McCauley (716871), Jou-Ku Chung, Eilish Brown (3232878), Jou-Ku Chung (716869), Bob Crooker   +9 more
core   +1 more source

Intrathecal use of amikacin: a case report

Brazilian Journal of Infectious Diseases
Meningitis caused by Acinetobacter baumannii is rare and are mostly hospital acquired after neurosurgical procedure. We report a case of a 40-year old man was admitted to the intensive care unit due to subarachnoid haemorrhage.
L. Barrou, B. Charra, A. Hachimi, B. Idali, A. Benslama, S. Motaouakkil   +5 more
doaj   +1 more source