Results 101 to 110 of about 99,994 (292)

The Configuration of the Perivascular System Transporting Macromolecules in the CNS

open access: yesFrontiers in Neuroscience, 2019
Large blood vessels entering the CNS are surrounded by perivascular spaces that communicate with the cerebrospinal fluid and, at their termini, with the interstitial space.
Beata Durcanova   +12 more
doaj   +1 more source

Neurochemical characterisation of lamina II inhibitory interneurons that express GFP in the PrP-GFP mouse [PDF]

open access: yes, 2013
Background Inhibitory interneurons in the superficial dorsal horn play important roles in modulating sensory transmission, and these roles are thought to be performed by distinct functional populations. We have identified 4 non-overlapping classes among
Garzillo, F.   +4 more
core   +2 more sources

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

Intrathecal/Intraventricular Linezolid in Multidrug-Resistant Enterococcus faecalis Ventriculitis

open access: yesJournal of Neurological Surgery Reports, 2016
Background The use of intrathecal antibiotic therapy for the treatment of ventriculitis and/or meningitis has demonstrated efficacy especially when sterilization of the cerebrospinal fluid is not possible with intravenous antibiotics alone ...
Brian F. Lich   +4 more
doaj   +1 more source

Effects of intrathecal opioids use in cesarean section on breastfeeding and newborns’ weight gaining [PDF]

open access: yes, 2016
Objective: To assess the association between intrapartum intrathecal opioid use and breastfeeding and weight gain following cesarean section. Materials and methods: The prospective double-blinded study was conducted on term pregnant women, undergoing ...
Anbarafshan, Mohammad   +6 more
core   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

The role of BK potassium channels in analgesia produced by alpha-2 adrenergic receptors [PDF]

open access: yes, 2016
BACKGROUND AND OBJECTIVE: Millions of people suffer from pain worldwide, and annually, great economic costs are imposed on societies for pain relief. Analgesics such as alpha-2 adrenergic receptor agonists, which have low risk of complications, can be ...
Attarzadeh-Yazd, G.   +2 more
core   +1 more source

Lyme Borreliosis During Pregnancy [PDF]

open access: yes, 2012
One of the authors (AL) presented a poster on 34 pregnancies of maternal Lyme borreliosis (Lb) in 1995. It was striking that untreated Lb associated with higher probability of adverse outcome but the number of patients were small and the statistical ...
Andrá, Norbert Solymosi
core   +2 more sources

New opportunities for bioscaffold‐enabled spinal cord injury repair

open access: yesBMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi   +11 more
wiley   +1 more source

Anesthesia for cystotomy in a dog with pancreatitis and a portosystemic shunt [PDF]

open access: yes, 2010
A 21-month-old Cocker spaniel with a portosystemic shunt, a moderate thrombocytopenia and a history of pancreatitis, was anesthetized for a cystotomy to remove bladder polyps and stones.
Brearley, JC   +3 more
core   +1 more source

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