Results 81 to 90 of about 74,181 (306)
Advanced Science, EarlyView.In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen +12 more
wiley +1 more source
Journal of Anaesthesiology Clinical Pharmacology, 2013 Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for ...
Shikha Gupta +3 more
doaj +1 more source
Epidural and Intrathecal Opioids [PDF]
Anaesthesia and Intensive Care, 1987 Small doses of epidural and intrathecal opioids produce effective and prolonged analgesia postoperatively, although the quality of analgesia does not differ from when conventional routes are used. The different opioids differ only in the speed of onset and duration of action, and in the incidence of side-effects.
openaire +2 more sources
, 2018 M Lv,1 P Zhang,2 Z Wang3 1Department of Obestetrics and Gynecology, Affiliated Women and Children’s Hospital of Jiaxing University, Jiaxing, China; 2Department of Anesthesiology, Affiliated Women and Children’s Hospital of Jiaxing University,
Lv M, Wang Z, Zhang P
core
Annals of Neurology, EarlyView.Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello +20 more
wiley +1 more source
Saudi Journal of Anaesthesia, 2013 Background: Intrathecal clonidine prolongs spinal anesthesia but the optimum dose to be used in cesarean delivery is not yet known. We evaluated the effect of addition of intrathecal clonidine to hyperbaric bupivacaine on postoperative pain after lower ...
Ranju Singh, Deepti Gupta, Aruna Jain
doaj +1 more source
, 2018 Shuai Miao,* Mengzhu Shi,* Lan Zou, Guanglei Wang Department of Anesthesiology, The Affiliated Hospital of XuZhou Medical University, XuZhou, JiangSu, China *These authors contributed equally to this work Objective: Intrathecal dexmedetomidine (DEX ...
Shi M, Zou L, Miao S, Wang G
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Annals of Neurology, EarlyView.Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto +12 more
wiley +1 more source
Intrathecal corticosteroids might slow Alzheimer’s disease progression
, 2008 Joseph Martin Alisky1,21Marshfield Clinic Research Foundation; 2Marshfield Clinic-Thorp Center, Marshfield, Wisconsin, USAAbstract: Anti-inflammatory drugs for treatment and prevention of Alzheimer’s disease have to date proved disappointing ...
Joseph Martin Alisky
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Errors involving patients receiving intrathecal chemotherapy
, 2010 Errors involving patients receiving intrathecal chemotherapy are a significant problem in oncology. Despite the improvement in the management of antineoplastic agents, unintentional intrathecal administration of chemotherapic drugs that are indicated ...
Scalzone, Maria +6 more
core +1 more source