AAV-mediated gene transfer to colon-innervating primary afferent neurons
Frontiers in Pain Research, 2023 Investigation of neural circuits underlying visceral pain is hampered by the difficulty in achieving selective manipulations of individual circuit components.
Reshma Gore +12 more
doaj +1 more source
Polyspecific, antiviral immune response distinguishes multiple sclerosis and neuromyelitis optica [PDF]
, 1887 Background: A polyspecific, intrathecal humoral immune response against neurotropic viruses such as measles, rubella and varicella zoster virus (MRZ reaction, MRZR) is present in 80--100% of patients with multiple sclerosis (MS), but has not to date been
Bergamaschi, R. +12 more
core +2 more sources
The Configuration of the Perivascular System Transporting Macromolecules in the CNS
Frontiers in Neuroscience, 2019 Large blood vessels entering the CNS are surrounded by perivascular spaces that communicate with the cerebrospinal fluid and, at their termini, with the interstitial space.
Beata Durcanova +12 more
doaj +1 more source
Pharmacology Research & Perspectives, 2023 This study was aimed at examining the anesthetic effects and spinal cord injuries in the rats by intrathecal injection of levobupivacaine at different concentrations.
Luyue Gao +5 more
doaj +1 more source
Intraspinal Drug Delivery Reservoir Refill Procedure by Non-Physician Clinicians: A Nation-Wide Survey of Training, Pocket Fill Experience, and Life-Long Learning Behaviors [PDF]
, 2016 Intraspinal drug delivery (IDD) is a safe and efficacious method used to deliver medications for the treatment of chronic neurologic disease that requires periodic reservoir refills that can place patients at risk for a rare, accidental but potentially ...
McGlothlen, Gail
core +1 more source
Safety and feasibility of Lin- cells administration to ALS patients : a novel view on humoral factors and miRNA profiles [PDF]
, 2018 Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes, however, are placed in growth factors that show neuroprotective abilities (e.g., nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and vascular
Baumert, Bartłomiej +12 more
core +2 more sources
International Journal of Preventive Medicine, 2012 Background: This study was performed to compare the effect of different doses of intrathecal meperidine on the incidence and intensity of shivering and other side-effects after spinal anesthesia for cesarean delivery.
Abdolreza Najafi Anaraki, Kamran Mirzaei
doaj
BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset [PDF]
, 2017 Background B lymphocytes are thought to play a relevant role in multiple sclerosis (MS) pathology. The in vivo analysis of intrathecally produced B cell-related cytokines may help to clarify the mechanisms of B cell recruitment and ...
Ermani, M. +11 more
core +1 more source
Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo [PDF]
, 2009 Background Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABAA) and metabotropic (GABAB) receptors.
Bernhard Bettler +9 more
core +3 more sources
Journal of Onco-Anaesthesiology and Perioperative MedicineBackground and Aims: This randomised double blinded comparative study of single bolus dose of epidural 0.2% ropivacaine with morphine versus intrathecal 0.2% ropivacaine with morphine was undertaken to evaluate their efficacy as intraoperative and ...
Nori Hari Chandan +2 more
doaj +1 more source