Results 81 to 90 of about 21,003 (255)

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Interface Design Based on Cognitive Load Theory

Деміург: ідеї, технології, перспективи дизайну
Purpose of the Article. This study aims to substantiate the principles of interface design based on cognitive load theory, with a focus on balancing the reduction of excessive perceptual complexity and providing users with control capabilities in ...
Павло Салига, Олексій Ситник   +1 more
doaj   +1 more source

Cognitive load in working memory on trigonometry Learning

Unnes Journal of Mathematics Education, 2018
The cognitive process involves three elements in the human memory system; sensory, working, and long term memory. Unless the long term memory does not have enough preliminary knowledge, the working memory will have difficulties in providing meaning and ...
Mochamad Abdul Basir, Hevy Risqi Maharanib   +1 more
doaj   +1 more source

Data‐Driven Design and Fabrication of Heat‐Resistant, Ultrastrong, Lightweight Aluminum‐Based Entropy Alloy by Additive Manufacturing

Advanced Science, EarlyView.
A data‐driven strategy integrating quantum machine learning (QML) and high‐throughput computing overcomes hot‐cracking limitation to design a novel lightweight aluminum‐based entropy alloy for additive manufacturing. The fabrication transforms brittle intermetallics into deformable hierarchical nanostructures, yielding ultrastrong strength (>1 GPa) and
Enmao Wang, Chao Ding, Danyang Zhou, Chenjin Xu, Swee Leong Sing, Jianzhong Jiang, Huibin Wu   +6 more
wiley   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source

Artificial Piezoelectric Interface Enables Ultrafast Interfacial Ion Kinetic for Highly‐Sensitive Piezoionic Sensors

Advanced Science, EarlyView.
This study proposes a piezoelectric interface modification strategy to amplify the piezoionic effect. The piezoelectric interface generates an intrinsic electric field, which not only drives rapid ion migration but also concentrates polarized ions on the interface. The flexible sensor delivers superior performance, such as a quick response rate, strong
Yanyu Chen, Xingyue Ling, Rizhong Gao, Xiaohong Zhang, Xi Chen, Chao Lu   +5 more
wiley   +1 more source

Bot or Not? Differences in Cognitive Load Between Human- and Chatbot-Led Post-Simulation Debriefings

Education Sciences
Understanding how different debriefing formats impact learner’s cognitive load is crucial for designing effective post-simulation reflection activities.
Dominik Evangelou, Miriam Mulders, Kristian Heinrich Träg   +2 more
doaj   +1 more source

Embedded Direct‐Written Organic Micro‐TEGs for High‐Efficiency Skin‐Heat Harvesting

Advanced Electronic Materials, EarlyView.
A finite‐element–guided design of direct‐written organic micro‐thermoelectric generators is presented for efficient skin‐heat harvesting. Embedding PEDOT:PSS/PBFDO thermoelectric legs within flexible substrates suppresses interfacial heat losses and enhances vertical heat flow.
Milad Jabri, Saeed Masoumi, Dimitrios Paparas, Mónica Acuautla, Luigi Giuseppe Occhipinti   +4 more
wiley   +1 more source

Turkish adaptation and psychometric evaluation of cognitive load scale for middle school students

Acta Psychologica
A psychological theory called the Cognitive Load Theory attempts to explain behavioral or psychological issues that emerge during instruction. The purpose of this study was to translate the cognitive load scale developed by Leppink et al.
Zeynep Çiğdem Özcan, Ayşe Tuğba Öner   +1 more
doaj   +1 more source