Results 271 to 280 of about 156,443 (294)

“Intrinsic Disorder”

2019
This volume gives voice to queer people from all faiths and no faiths, and their heterosexual allies, describing their experiences with spiritual violence and inclusion. It includes personal narratives, theoretical insights, and creative writing, highlighting stories of pain, rejection, joy, and transformation.
openaire   +1 more source

Druggability of Intrinsically Disordered Proteins

2015
Although the proteins in all the current major classes considered to be druggable are folded in their native states, intrinsically disordered proteins (IDPs) are becoming attractive candidates for therapeutic intervention by small drug-like molecules.
Priyanka, Joshi, Michele, Vendruscolo
openaire   +2 more sources

Translocation of polyampholytes and intrinsically disordered proteins⋆

The European Physical Journal E, 2018
Polyampholytes are polymers carrying electrical charges of both signs along their backbone. We consider synthetic polyampholytes with a quenched random charge sequence and intrinsically disordered proteins, which have a well-defined charge sequence and behave like polyampholytes in the denaturated state.
Johner, Albert, Joanny, Jean-François
openaire   +3 more sources

Intrinsically disordered proteins: regulation and disease

Current Opinion in Structural Biology, 2011
Intrinsically disordered proteins (IDPs) are enriched in signaling and regulatory functions because disordered segments permit interaction with several proteins and hence the re-use of the same protein in multiple pathways. Understanding IDP regulation is important because altered expression of IDPs is associated with many diseases. Recent studies show
Babu, M.M., Lee, R.T.J.G. van der, Groot, N.S. de, Gsponer, J.   +3 more
openaire   +2 more sources

Intrinsically disordered CO2 sensors

Nature Cell Biology, 2022
Ryan J. Emenecker, Alex S. Holehouse
openaire   +2 more sources

Resources for computational prediction of intrinsic disorder in proteins

Methods, 2022
Lukasz Kurgan
exaly  

Overview Update: Computational Prediction of Intrinsic Disorder in Proteins

Current Protocols, 2023
Vladimir N Uversky, Lukasz Kurgan
exaly  

IDPology of the living cell: intrinsic disorder in the subcellular compartments of the human cell

Cellular and Molecular Life Sciences, 2020
Bi Zhao, Akila Katuwawala, Vladimir N Uversky   +2 more
exaly  

Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder

Molecular Systems Biology, 2020
Lovisa Åkesson, Diana Mahdessian, Christian Gnann   +2 more
exaly  

Intrinsic Disorder and Protein Function

Biochemistry, 2002
A Keith, Dunker, Celeste J, Brown, J David, Lawson, Lilia M, Iakoucheva, Zoran, Obradović   +4 more
openaire   +2 more sources