Results 51 to 60 of about 1,811,289 (287)
Structural Disorder Provides Increased Adaptability for Vesicle Trafficking Pathways [PDF]
, 2013 Vesicle trafficking systems play essential roles in the communication between the organelles of eukaryotic cells and also between cells and their environment.
Peter Tompa +11 more
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Intrinsic disorder in the kinesin superfamily
Biophysical Reviews, 2012 Kinesin molecular motors perform a myriad of intracellular transport functions. While their mechanochemical mechanisms are well understood and well-conserved throughout the superfamily, the cargo-binding and regulatory mechanisms governing the activity of kinesins are highly diverse and in general, are incompletely characterized.
Mark A, Seeger, Sarah E, Rice
openaire +3 more sources
Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease
Frontiers in Genetics, 2013 Whereas many cases of neurodegenerative disease feature the abnormal accumulationof protein, an abundance of recent literature highlights loss of RNA homeostasis as aubiquitous and central feature of pathological states.
Douglas eGray +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Intravascular processing of triglyceride-rich lipoproteins (TRLs) is crucial for delivery of dietary lipids fueling energy metabolism in heart and skeletal muscle and for storage in white adipose tissue.
Kristian Kølby Kristensen +13 more
doaj +1 more source
Intrinsically Disordered Proteins in Neurodegeneration [PDF]
Biophysical Journal, 2016 Intrinsically disordered proteins (IDPs) have gained wide recognition due to their versatile roles in cell physiology and pathology. A large repertoire of IDPs has been implicated in numerous diseases, making them potential targets for therapeutic intervention.
openaire +2 more sources
MobiDB: intrinsically disordered proteins in 2021 [PDF]
Nucleic Acids Research, 2020 AbstractThe MobiDB database (URL: https://mobidb.org/) provides predictions and annotations for intrinsically disordered proteins. Here, we report recent developments implemented in MobiDB version 4, regarding the database format, with novel types of annotations and an improved update process.
Damiano Piovesan +14 more
openaire +9 more sources
Interaction of external, introjected, and identified regulation with intrinsic motivation in exercise: Relationships with exercise enjoyment [PDF]
, 2005 The present study examined the way in which the exercise-related motives of external regulation, introjected regulation, and identified regulation interacted with intrinsic motivation to relate to exercise enjoyment.
Vlachopoulos, SP, Karageorghis, CI
core +6 more sources
eLife, 2017 Scaffolding the calcium/calmodulin-dependent phosphatase 2B (PP2B, calcineurin) focuses and insulates termination of local second messenger responses.
Patrick J Nygren +9 more
doaj +1 more source
Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders [PDF]
Frontiers in Aging Neuroscience, 2015 The recent years have witnessed a rise in the number of intrinsically disordered proteins (IDPs), also known as hybrid proteins, which possess both structured domains and biologically important intrinsically disordered protein regions (IDPRs). These proteins challenge the “one sequence—one structure—one function” concept by demonstrating that the lack ...
Vladimir N. Uversky +3 more
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D2P2: database of disordered protein predictions [PDF]
, 2013 We present the Database of Disordered Protein Prediction (D2P2), available at http://d2p2.pro (including website source code). A battery of disorder predictors and their variants, VL-XT, VSL2b, PrDOS, PV2, Espritz and IUPred, were run on all protein ...
Oates, Matt E. +3 more
core +1 more source