Results 131 to 140 of about 15,260 (267)

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Invariant natural killer T cells and iron metabolism orchestrate skin development and homeostasis. [PDF]

Cell Mol Immunol, 2023
Nabeshima H, Niitsu T, Fukushima K, Kida H.   +3 more
europepmc   +1 more source

A Novel Approach Based on Acceptor–Donor–Acceptor Type Molecules Enhances the Therapeutic Efficacy and Safety of Photothermal Therapy for Osteosarcoma

Advanced Science, EarlyView.
Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin, Hongru Wang, Yi Yang, Yuhang Xie, Yuan Zhang, Zhiye Du, Yi Huang, Wei Guo, Yang Li, Shidong Wang   +9 more
wiley   +1 more source

Immune cells and preterm labour:do invariant NKT cells hold the key? [PDF]

, 2015
Rossi, A G, Saunders, Philippa; id_orcid, Rinaldi, S F, Saunders, P T K, Norman, J E   +4 more
core   +1 more source

Invariant natural killer T cells and incidence of first-time coronary events: a nested case-control study. [PDF]

Eur Heart J Open, 2023
Tomas L, Katra P, Badn W, Andersson L, Nilsson J, Schiopu A, Engelbertsen D, Gonçalves I, Bengtsson E, Björkbacka H.   +9 more
europepmc   +1 more source

Trophic Diversity in Duckweed: Mixotrophy, More Than the Sum of its Extremes

Advanced Science, EarlyView.
In the context of rising DOC in aquatic environments, mixotrophic duckweed may impact carbon cycling by acting as either a carbon sink, as they absorb CO2 through photosynthesis, or a carbon source, as they release CO2 through respiration of absorbed DOC, which depends on DOC concentration, light availability, temperature, and other environmental ...
Zuoliang Sun, Yan Chen, Fajun Li, Xuyao Zhao, Qingxiang Han, Hongwei Hou   +5 more
wiley   +1 more source

Dendritic cells are targets for human invariant Valpha24+ natural killer T-cell cytotoxic: An important immune regulatory function

, 2000
Objective. Human invariant Vα24+ natural killer T (NKT) cells, a subpopulation of NK cell-receptor (NKR-P1A)-expressing T cells with an invariant Vα24JαQ T-cell receptor (TCR), are stimulated by the glycolipid a-galactosylceramide (KRN7000), in a CD1d ...
Suzuki, K., Durrant, S. T., Nieda, M., Nicol, A. J., Tadokoro, K., Takeo Juji, Simon Durrant, Mie Nieda, Andrew Nicol, Kenji Suzuki, Steven Porcelli, Porcelli, S., Kenji Tadokoro, Juji, T., Koezuka, Y., Yasuhiko Koezuka   +15 more
core   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

Advanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu, Rui Xu, Quan Wu, Tian‐Xin Xiao, Lai‐Xi Zhao, Lei Sun, Ya‐Wen Zheng, Liang Dong, Zhi‐Quan Tian, Haibo Wang   +9 more
wiley   +1 more source

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

, 2011
Natural killer T cells (NKT cells) recognize glycolipid antigens presented by CD1d. These cells express an evolutionarily conserved, invariant T cell antigen receptor (TCR), but the forces that drive TCR conservation have remained uncertain. Here we show
Chi-Huey, Wong, Kawakami, K, Enrico Girardi, Bo Pei, Vela, JL, Andrew, PW, Petr Illarionov, Archana Khurana, Dirk M Zajonc, Samira Dahesh, Pei, B, Kronenberg, M, Kazuyoshi Kawakami, Kazuyoshi Kawahara, Paul Rogers, Yuki Kinjo, Masakazu Imamura, Moriya Tsuji, Mitchell Kronenberg, Dahesh, S, Uchiyama, S, Tsuji, M, Okawara, A, Anaximandro Gómez-Velasco, Satoshi Uchiyama, Besra, Gurdyal; id_orcid, Akiko Okawara, Girardi, E, Kaneko, Y, Nizet, V, Illarionov, P, Yali Li, Yoshitsugu Miyazaki, Khurana, A, Victor Nizet, José Luis Vela, Chi-Huey Wong, Kawahara, K, Peter W Andrew, Miyazaki, Y, Xiangming Li, Gurdyal S Besra, Imamura, M, Rogers, P, Yesilkaya, H, Yukihiro Kaneko, Zajonc, DM, Hasan Yesilkaya, Kinjo, Y, Li, Y, Li, X, Gomez-Velasco, A   +51 more
core   +1 more source

Identification of altered immune cell types and molecular mechanisms in Alzheimer’s disease progression by single-cell RNA sequencing

Frontiers in Aging Neuroscience
IntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by gradual loss of cognitive function. Understanding the molecular mechanisms is crucial for developing effective therapies.MethodsData from single-cell RNA ...
Hua Lin, Li Su, Daniel Mao, Grace Yang, Qi Huang, Yating Lan, Jingyi Zeng, Wenyi Song, Guining Liang, Qingyan Wei, Donghua Zou, Rongjie Li, Chanhua Zou   +12 more
doaj   +1 more source