Results 121 to 130 of about 75,921 (210)

Regulation of the terminal maturation of iNKT cells by mediator complex subunit 23

Nature Communications, 2018
Invariant Natural Killer T cells (iNKT) rapidly exert effector functions upon activation, but the mechanisms of their functional maturation remain to be determined.
Yu Xu, Yang Sun, Hao Shen, Yuling Dai, Haifeng Liu, Ronghong Li, Hongdao Zhang, Ligang Wu, Xiaoyan Zhu, Xiaolong Liu   +9 more
doaj   +1 more source

SPLENIC INVARIANT NATURAL KILLER T CELLS PLAY A SIGNIFICANT ROLE IN THE RESPONSE TO POLYMICROBIAL SEPSIS. [PDF]

Shock, 2023
Heffernan DS, Chung CS, Ayala A.
europepmc   +1 more source

Kinetics and cellular site of glycolipid loading control [PDF]

, 2009
CD1d-restricted natural killer T cells (NKT cells) possess a wide range of effector and regulatory activities that are related to their ability to secrete both T helper 1 (Th1) cell- and Th2 cell-type cytokines.
Arora, Pooja, Baena, Andres, Baine, Ian, Bricard, Gabriel, Goldberg, Michael F., Im, Jin S., Jerud, Elliot S., Molano, Alberto, Ndonye, Rachel M., Venkataswamy, Manjunatha M., Yu, Karl O.A.   +10 more
core  

Invariant natural killer T cells and incidence of first-time coronary events: a nested case-control study. [PDF]

Eur Heart J Open, 2023
Tomas L, Katra P, Badn W, Andersson L, Nilsson J, Schiopu A, Engelbertsen D, Gonçalves I, Bengtsson E, Björkbacka H.   +9 more
europepmc   +1 more source

Invariant natural killer T cells in multiple sclerosis

, 2013
Invariant natural killer T (iNKT) cells are a subpopulation of lymphocytes that express both a CD1d-restricted αβ T cell receptor (TCR) and NK cell markers. iNKT cell perturbations are implicated in a wide variety of autoimmune diseases including Multiple Sclerosis (MS).
openaire   +3 more sources

Invariant natural killer T cells and iron metabolism orchestrate skin development and homeostasis. [PDF]

Cell Mol Immunol, 2023
Nabeshima H, Niitsu T, Fukushima K, Kida H.   +3 more
europepmc   +1 more source

The Role Of Invariant Natural Killer T Cells In Cancer

, 2013
Invariant natural killer T (iNKT) cells are a unique subset of T lymphocytes that recognize glycolipid antigens presented by the class I-like non-polymorphic histocompatibility complex (MHC) molecule, CD1d. They express both innate and adaptive immune cells’ surface receptors, but act more like cells of the innate immune system.
Nur, Haneen, Van Valckenborgh, Els, De Bruyne, Elke, Vanderkerken, Karin, Menu, Eline   +4 more
openaire   +2 more sources

Identification of altered immune cell types and molecular mechanisms in Alzheimer’s disease progression by single-cell RNA sequencing

Frontiers in Aging Neuroscience
IntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by gradual loss of cognitive function. Understanding the molecular mechanisms is crucial for developing effective therapies.MethodsData from single-cell RNA ...
Hua Lin, Li Su, Daniel Mao, Grace Yang, Qi Huang, Yating Lan, Jingyi Zeng, Wenyi Song, Guining Liang, Qingyan Wei, Donghua Zou, Rongjie Li, Chanhua Zou   +12 more
doaj   +1 more source

Significance of frequencies, compositions and/or antileukemic activity of (DC-stimulated) invariant NKT, NK and CIK cells on the outcome of patients with AML, ALL and CLL [PDF]

, 2018
Invariant natural killer cells (iNKT cells), natural killer cells (NKT cells) and cytokine induced killer cells (CIK cells) and their subsets are important for immune-surveillance.
Böck, Corinna Lesley
core  

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells. [PDF]

JCI Insight, 2023
Engelen SE, Ververs FA, Markovska A, Lagerholm BC, Kraaijenhof JM, Yousif LI, Zurke YX, Gulersonmez CM, Kooijman S, Goddard M, van Eijkeren RJ, Jervis PJ, Besra GS, Haitjema S, Asselbergs FW, Kalkhoven E, Ploegh HL, Boes M, Cerundolo V, Hovingh GK, Salio M, Stigter EC, Rensen PC, Monaco C, Schipper HS.   +24 more
europepmc   +1 more source