Results 121 to 130 of about 2,646,419 (299)

Fetuin B overexpression suppresses proliferation, migration, and invasion in prostate cancer by inhibiting the PI3K/AKT signaling pathway

, 2020
Kai Zhan, Rui Liu, Hang Tong, Shun Gao, Guang Yang, Arman Hossain, Tinghao Li, Weiyang He   +7 more
openalex   +1 more source

Naturalization and invasion of alien plants: concepts and definitions

, 2000
D. Richardson, P. Pyšek, M. Rejmánek, M. Barbour, F. Panetta, C. J. West   +5 more
semanticscholar   +1 more source

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

Cell, 2006
J. Condeelis, J. Pollard
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Genetically modified adipose tissue−derived mesenchymal stem cells overexpressing CXCR4 display increased motility, invasiveness, and homing to bone marrow of NOD/SCID mice

, 2011
Sylwia Bobis‐Wozowicz, Katarzyna Miękus, Ewa Wybieralska, Danuta Jarocha, Artur Zawisz, Zbigniew Madeja, Marcin Majka   +6 more
openalex   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Morphological evidence for an invasion-independent metastasis pathway exists in multiple human cancers [PDF]

, 2004
Takashi Sugino, Tomiko Yamaguchi, Go Ogura, Atsuko Saito, Takeaki Hashimoto, Nobuo Hoshi, Sayaka Yoshida, Steve Goodison, Toshimitsu Suzuki   +8 more
openalex   +1 more source

MicroRNA-96-5p promotes proliferation, invasion and EMT of oral carcinoma cells by directly targeting FOXF2 [PDF]

, 2020
Haiyan Wang, Ning Ma, Wenyue Li, Zuomin Wang   +3 more
openalex   +1 more source