Results 11 to 20 of about 41,736 (257)
Computational investigation of IP3 diffusion
Scientific Reports, 2023 Inositol 1,4,5-trisphosphate (IP3) plays a key role in calcium signaling. After stimulation, it diffuses from the plasma membrane where it is produced to the endoplasmic reticulum where its receptors are localized. Based on in vitro measurements, IP3 was
Roberto Ornelas-Guevara +3 more
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Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity [PDF]
Current Biology, 1997 Ca2+ waves allow effective delivery of intracellular Ca2+ signals to cytosolic targets. Propagation of these regenerative Ca2+ signals probably results from the activation of intracellular Ca2+ channels by the increase in cytosolic [Ca2+] that follows the opening of these channels. Such positive feedback is potentially explosive.
Marchant, Jonathan S., Taylor, Colin W.
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Journal of Pharmacological Sciences, 2008 The inositol 1,4,5-trisphosphate receptors (IP3Rs) form clusters following agonist stimulation, but its mechanism remains controversial. In this study, we visualized the clustering of green fluorescent protein (GFP)-tagged type 3 IP3R (GFP-IP3R3) in ...
Yosuke Tojyo +3 more
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IP3 – Progress towards a Global ICT Profession [PDF]
, 2010 The International Professional Practice Partnership (IP3) was formed by the International Federation for Information processing (IFIP) in 2007 to fulfill the objective of creating a global ICT profession. This start of this programme were first presented at WCC 2008 in Milan and since then major advances have taken place - both in the collective ...
Johnson, Roger +2 more
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, 2022 Alcohol-related liver fibrosis (ALF) is a form of alcohol-related liver disease (ALD) that generally occurs in response to heavy long-term drinking. Ecto-5′-nucleotidase (NT5E), also known as CD73, is a cytomembrane protein linked to the cell membrane ...
Mengda Zhang (12882494) +11 more
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Біологічні студії, 2012 The influence of IP3 on Ca2+-, Na+,K+-ATPase and basal Mg2+-ATPase activity of rat hepatocytes membranes was studied in control and after perfusion of liver by insulin-containing solution.
S. Bychkova, T. Chorna
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iScience, 2020 Summary: Ca2+ oscillations that depend on inositol-1,4,5-trisphosphate (IP3) have been ascribed to biphasic Ca2+ regulation of the IP3 receptor (IP3R) or feedback mechanisms controlling IP3 levels in different cell types.
Paula J. Bartlett +3 more
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Decavanadate displaces inositol 1,4,5-trisphosphate (IP3) from its receptor and inhibits IP3 induced Ca2+ release in permeabilized pancreatic acinar cells [PDF]
, 1991 Inositol 1,4,5-trisphosphate (IP3) induced Ca2+ release in digitonin permeabilized rat pancreatic acinar cells is specifically inhibited by decavanadate.
M. Gratzl +9 more
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Agonist-evoked Ca2+ wave progression requires Ca2+ and IP3
, 2010 Smooth muscle responds to IP3-generating agonists by producing Ca2+ waves. Here, the mechanism of wave progression has been investigated in voltage-clamped single smooth muscle cells using localized photolysis of caged IP3 and the caged Ca2+ buffer diazo-
Olson, M.L. +3 more
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G3: Genes, Genomes, Genetics, 2016 Inositol 1,4,5-trisphosphate (IP3) regulates a host of biological processes from egg activation to cell death. When IP3-specific receptors (IP3Rs) bind to IP3, they release calcium from the ER into the cytoplasm, triggering a variety of cell type- and ...
Derek M. Dean +5 more
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