Results 21 to 30 of about 41,736 (257)
Pharmaceutical Biology, 2018 Context: Quercetin (QCT) has been known as a potential therapeutic strategy for gastrointestinal diseases because it contributes to the stabilization of mast cells, the prevention of histamine release and modulation of CaCC chloride channel.
Ji Eun Kim +9 more
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Phospholipase C-β1 and β4 contribute to non-genetic cell-to-cell variability in histamine-induced calcium signals in HeLa cells. [PDF]
PLoS ONE, 2014 A uniform extracellular stimulus triggers cell-specific patterns of Ca(2+) signals, even in genetically identical cell populations. However, the underlying mechanism that generates the cell-to-cell variability remains unknown.
Sachiko Ishida +4 more
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IP3 receptors: Take four IP3 to open. [PDF]
, 2016 Inositol 1,4,5-trisphosphate receptors (IP3Rs) and ryanodine receptors are the channels responsible for Ca(2+)release from the endoplasmic and sarcoplasmic reticulum.
core +2 more sources
Breast Cancer-Derived AZU1 Educates Neutrophils to Promote Tumor Progression and Metastasis Through PAD4-Dependent Extracellular Trap Formation. [PDF]
Mol CarcinogABSTRACT Neutrophil extracellular traps (NETs) play crucial roles in cancer progression, but their regulatory mechanisms in breast cancer remain poorly understood. We developed a NETs‐related prognostic risk model using TCGA breast cancer data and identified key biomarkers through bioinformatics analysis.
Huang Z +9 more
europepmc +2 more sources
Dual-FRET imaging of IP3 and Ca2+ revealed Ca2+-induced IP3 production maintains long lasting Ca2+ oscillations in fertilized mouse eggs [PDF]
, 2019 In most species, fertilization induces Ca(2+) transients in the egg. In mammals, the Ca(2+) rises are triggered by phospholipase Czeta (PLCzeta) released from the sperm; IP3 generated by PLCzeta induces Ca(2+) release from the intracellular Ca(2+) store ...
Shirakawa, Hideki +7 more
core +2 more sources
On the partition property of measures on Pℋλ
International Journal of Mathematics and Mathematical Sciences, 1982 The partition property for measures on Pℋλ was formulated by analogy with a property which Rowbottom [1] proved was possessed by every normal measure on a measurable cardinal. This property has been studied in [2], [3], and [4].
Donald H. Pelletier
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Measurement of Inositol Triphosphate Levels from Rat Hippocampal Slices
Bio-Protocol, 2016 Inositol triphosphate (IP3) is an important second messenger that participates in signal transduction pathways in diverse cell types including hippocampal neurons.
Nino Tabatadze, Catherine Woolley
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ADP stimulates IP3 formation in human platelets [PDF]
, 1986 Aspirinated human platelets labeled with 32PO4 showed a 1.7-fold increase in [32P]IP3 when stimulated with ADP. ADP-stimulated mobilization of internal Ca2+ and phosphorylation of myosin were enhanced in the presence of extracellular Ca2+ but the ...
Carol A. Dangelmaier +7 more
core +1 more source
Biophysics and Physicobiology, 2019 Inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) is a huge tetrameric intracellular Ca2+ channel that mediates cytoplasmic Ca2+ signaling. The structural basis of the gating in IP3R has been studied by X-ray crystallography and cryo-electron microscopy,
Kei Moritsugu +2 more
doaj +1 more source
PLoS ONE, 2021 Alzheimer's disease (AD) is a devastating illness affecting over 40 million people worldwide. Intraneuronal rise of amyloid beta in its oligomeric forms (iAβOs), has been linked to the pathogenesis of AD by disrupting cytosolic Ca2+ homeostasis. However,
Joseph Minicucci +4 more
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