Results 31 to 40 of about 41,736 (257)
Non-inositol 1,4,5-trisphosphate (IP3) receptor IP3-binding proteins
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2023 Conventionally, myo-D-inositol 1, 4,5-trisphosphate (IP3) is thought to exert its second messenger effects through the gating of IP3R Ca2+ release channels, located in Ca2+-storage organelles like the endoplasmic reticulum. However, there is considerable indirect evidence to support the concept that IP3 might interact with other, non-IP3R proteins ...
openaire +2 more sources
IP3 signalling regulates exogenous RNAi in Caenorhabditis elegans. [PDF]
, 2015 RNA interference (RNAi) is a widespread and widely exploited phenomenon. Here, we show that changing inositol 1,4,5-trisphosphate (IP3) signalling alters RNAi sensitivity in Caenorhabditis elegans.
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Excluded-Mean-Variance Neural Decision Analyzer for Qualitative Group Decision Making
Advances in Fuzzy Systems, 2012 Many qualitative group decisions in professional fields such as law, engineering, economics, psychology, and medicine that appear to be crisp and certain are in reality shrouded in fuzziness as a result of uncertain environments and the nature of human ...
Ki-Young Song +3 more
doaj +1 more source
Synthesis and two-photon photolysis of 6-(ortho-nitroveratryl)-caged IP3 in living cells
, 2006 The synthesis of a photolabile derivative of inositol-1,4,5-trisphosphate (IP3) is described. This new caged second messenger (6-ortho-nitroveratryl)-IP3 (6-NV-IP3) has an extinction coefficient of 5000 M(-1) cm(-1) at 350 nm, and a quantum yield of ...
Ogrodnik, Jakob +5 more
core +1 more source
A Direct Interaction between IP3 Receptors and Myosin II Regulates IP3 Signaling in C. elegans [PDF]
, 2002 Molecular and physiological studies of cells implicate interactions between the cytoskeleton and the intracellular calcium signalling machinery as an important mechanism for the regulation of calcium signalling [1–11].
Lockwood, Katherine C +3 more
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Toxins, 2019 A novel Bacillus thuringiensis Cry protein, Cry8Hb, active against Diabrotica virgifera virgifera (Western corn rootworm, WCRW) was discovered. Unexpectedly, the anti-rootworm activity of the Cry8Hb toxin was enhanced significantly by fusing Escherichia ...
Jingtong Hou +8 more
doaj +1 more source
eLife, 2023 Loss of endoplasmic reticular (ER) Ca2+ activates store-operated Ca2+ entry (SOCE) by causing the ER localized Ca2+ sensor STIM to unfurl domains that activate Orai channels in the plasma membrane at membrane contact sites (MCS).
Pragnya Chakraborty +7 more
doaj +1 more source
, 2005 Smooth muscle responds to IP3-generating (sarcolemma acting) neurotransmitters and hormones by releasing Ca2+ from the sarcoplasmic reticulum (SR) via IP3 receptors (IP3Rs). This release may propagate as Ca2+ waves.
Muir, T.C. +7 more
core +4 more sources
Journal of International Medical Research, 2019 Objective The second messenger inositol triphosphate (IP3) is involved in signal transduction in multiple cell types. We evaluated the effects of high-dose levocetirizine on chronic spontaneous urticaria (CSU) and examined the significance of serum IP3 ...
Xianqiong Huang +2 more
doaj +1 more source
KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals
Nature Communications, 2021 Calcium signals initiated by IP3 receptors in ER membranes regulate most cellular activities. Here, the authors show that KRas-induced actininteracting protein (KRAP) tethers a small subset of IP3 receptors to actin and licenses them to evoke cytosolic ...
Nagendra Babu Thillaiappan +3 more
doaj +1 more source