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iMeta, Volume 4, Issue 5, October 2025.Interactions between functional oligosaccharides and small intestinal cells are increasingly recognized as critical for maintaining intestinal health. Using xylooligosaccharides (XOS) as a model, we demonstrate that XOS promote growth in piglets primarily by enhancing nutrient transport and increasing villus height in the jejunum.
Fuli Deng +8 more
wiley +1 more source
Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells [PDF]
, 2016 Oregano essential oil (OEO) has long been used to improve the health of animals, particularly their intestinal health. The health benefits of OEO are generally attributed to antioxidative actions, but the mechanisms remain unclear.
Hongkui Wei, Jian Peng, Jun Wang, Yi Zou
core +2 more sources
Journal of Animal Science and TechnologyThis study investigated the cytotoxicity of illite and bentonite using porcine intestinal epithelial cells (IPEC-J2) as a primary screening verification method for the effect of supplementing illite and bentonite.
Seyeon Chang +7 more
doaj +1 more source
Quercetin inhibits porcine intestinal inflammation in vitro [PDF]
, 2019 Purpose: To investigate the effect of Quercetin (Que) on inflammatory reaction in intestinal porcine enterocyte cells, IPEC-J2, induced by lipopolysaccharide (LPS).Methods: IPEC-J2 cells were pretreated with Que and then incubated with LPS.
Chen, Hui-Yu +5 more
core +2 more sources
Academia BiologyIn the swine industry, the increased awareness of the in-feed use of antibiotics due to the emergence of resistant bacteria led to an intense search for alternative strategies.
José D. Uezen +7 more
doaj +1 more source
Caenorhabditis elegans and probiotics interactions from a prolongevity perspective [PDF]
, 2019 Probiotics exert beneficial effects on host health through different mechanisms of action, such as production of antimicrobial substances, competition with pathogens, enhancement of host mucosal barrier integrity and immunomodulation.
Barbara Guantario +5 more
core +1 more source
Role of gut microbiota-generated short chain fatty acids in metabolic and cardiovascular health [PDF]
, 2018 Purpose of this Review: This review assesses the latest evidence linking short-chain fatty acids (SCFA) with host metabolic health and cardiovascular disease (CVD) risk and presents the latest evidence on possible biological mechanisms.
Chambers, Edward S. +3 more
core +1 more source
Preliminary Characterization of the Transcriptional Response of the Porcine Intestinal Cell Line IPEC-J2 to EnterotoxigenicEscherichia coli,Escherichia coli, andE. coliLipopolysaccharide [PDF]
, 2010 IPEC-J2, a promisingin vitromodel system, is not well characterized especially on the transcriptional level, in contrast to human counterparts. The aim of this study was to characterize the gene expression in IPEC-J2 cells when coincubated with ...
Marisa M. Geens, Theo A. Niewold
core +1 more source
Isolation of equine endothelial cells and life cell angiogenesis assay [PDF]
, 2014 Arterial or venous thromboses are frequent clinical complications with the risk of fatal progression. Recent studies suggest the disruption of angiogenesis in the course of thrombus resolution as the underlying pathomechanism.
Dietze, Kathrin +5 more
core +1 more source
Animal NutriomicsPorcine small intestinal epithelial cell line (IPEC-J2) is a good research model exploring the impact of feed additives on intestinal epithelial cells. Monobutyrin (MB), as a derivative of butyric acid (BA), overcomes the shortcomings of BA.
Haidong Wang +6 more
doaj +1 more source