Results 101 to 110 of about 22,373 (186)

Deoxynivalenol Induces Inflammation in IPEC-J2 Cells by Activating P38 Mapk And Erk1/2

, 2020
Fusarium-derived mycotoxin deoxynivalenol (DON) usually induces diarrhea, vomiting and gastrointestinal inflammation. We studied the cytotoxic effect of DON on porcine small intestinal epithelium using the intestinal porcine epithelial cell line IPEC-J2.
Xiwen Deng, Hua Zhang, Haibin Zhang, Chuang Zhou, Wenda Wu   +4 more
core   +1 more source

Lack of LTβR Increases Susceptibility of IPEC-J2 Cells to Porcine Epidemic Diarrhea Virus

, 2018
The essential requirement of the lymphotoxin beta receptor (LTβR) in the development and maintenance of peripheral lymphoid organs is well recognized. Evidence shows that LTβR is involved in various cellular processes; however, whether it plays
Kui Li, Yanfang Wang, Tawfeek Altawaty, Lulu Liu, Hongyong Zhang, Cong Tao, Shaohua Hou   +6 more
core   +1 more source

Monobutyrin enhances the functionality of tight junctions and alleviates the IPEC-J2 cells barrier damage induced by lipopolysaccharide stimulation

Animal Nutriomics
Porcine small intestinal epithelial cell line (IPEC-J2) is a good research model exploring the impact of feed additives on intestinal epithelial cells. Monobutyrin (MB), as a derivative of butyric acid (BA), overcomes the shortcomings of BA.
Haidong Wang, Minyao Zhou, Ji Qiu, Yanqiu Luo, Xinyu Li, Jintian He, Minqi Wang   +6 more
doaj   +1 more source

Correction: Trolox and Ascorbic Acid Reduce Direct and Indirect Oxidative Stress in the IPEC-J2 Cells, an In Vitro Model for the Porcine Gastrointestinal Tract

, 2015
Correction: Trolox and Ascorbic Acid Reduce Direct and Indirect Oxidative Stress in the IPEC-J2 Cells, an In Vitro Model for the Porcine Gastrointestinal ...
PLOS ONE (2189197)
core   +1 more source

Analysis of cell cycle specific genes on mRNA and protein level.

, 2015
The expression of p53 was analysed by microarray, qPCR and Western blot. (A) IPEC-J2 showed a 27.4 fold increase of the p53-mRNA level in comparison to IPEC-1. This was confirmed by qPCR and a 300-fold increase was detected in IPEC-J2. On the other hand,
Constanze Nossol (326870), Anne-Kathrin Diesing (326868), Nicole Reinhardt (766263), Werner Zuschratter (80107), Klaus Wimmers (82199), Stefan Kahlert (326881), Anicò Barta-Böszörményi (766261), Heidi Faber-Zuschratter (766262), Siriluk Ponsuksili (732948), Hermann-Josef Rothkötter (64047)   +9 more
core   +1 more source

In vitro immunomodulatory effects of thymol and cinnamaldehyde in a pig intestinal epithelial cell line (IPEC-J2)

, 2020
Thymol and cinnamaldehyde are phytogenic feed additives developed to improve gut health and growth performance in poultry and swine. This study evaluated the in vitro immune modulating effects of thymol and cinnamaldehyde blend (TCB) in a porcine gut ...
P.B. Rasmussen, K.M. Kragh, C. Shen, L.G. Christensen   +3 more
core   +1 more source

Tea Polyphenols Relieve the Fluoride-Induced Oxidative Stress in the Intestinal Porcine Epithelial Cell Model

Toxics
Prolonged excessive intake of fluoride (F) can result in fluorosis, leading to a range of tissue oxidative damages. Therefore, mitigating the oxidative stress induced by fluorosis has become a significant research concern.
Chunyan Xie, Shuyi Niu, Wen Tian
doaj   +1 more source

Air–liquid interface enhances oxidative phosphorylation in intestinal epithelial cell line IPEC-J2

, 2017
The intestinal porcine epithelial cell line IPEC-J2, cultured under the air–liquid interface (ALI) conditions, develops remarkable morphological characteristics close to intestinal epithelial cells in vivo.
Wolter, Romina, Kröber, Andrea, Romina Wolter, Hermann-Josef Rothkötter, Berend Isermann, Isermann, Berend, Wimmers, Klaus, Klasvogt, Sonja, Nossol, Constanze, Schmidt, Anke, Anke Schmidt, Sandra Vorwerk, Constanze Nossol, Rothkötter, Hermann-Josef, Andrea Kröber, Vorwerk, Sandra, Werner Zuschratter, Zuschratter, Werner, Sonja Klasvogt, Klaus Wimmers   +19 more
core   +1 more source

Epigenomic determinants of ferroptosis via oxidative stress in IPEC-J2 cells exposed to Ochratoxin A

Ecotoxicology and Environmental Safety
The intestinal epithelium serves as a frontline defense against dietary contaminants, such as Ochratoxin A (OTA), a mycotoxin linked to oxidative stress and cell death. OTA Toxicity is well documented; however, the epigenetic mechanisms driving its effects through chromatin remodeling and histone H3K27ac modifications remain poorly understood.
Shaokat Ali, Omnia Fathy Abdelkarim, Ranzhuo Kuang, Ali Hassan Nawaz, Wang DaoYuan, Mehboob Ahmad, Muhammad Farhan Rahim, Farah Ijaz, Zhu MengJin   +8 more
openaire   +2 more sources

Dynamic Mechanical Load as a Trigger for Growth and Proliferation in Porcine Epithelial Cells

Biomolecules
The impact of gravity is a basic force determining our existence on Earth. Changes in orientation with respect to the gravity vector trigger alternating mechanical forces on organisms, organs, and cells. In the intestines of mammals, epithelial cells are
Stefan Kahlert, Constanze Nossol, Marcus Krüger, Sascha Kopp, Daniela Grimm, Simon L. Wuest, Hermann-Josef Rothkötter   +6 more
doaj   +1 more source