Results 51 to 60 of about 3,566 (193)

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

open access: yesThe FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki   +7 more
wiley   +1 more source

Treatment of ipRGCs with the GRK2/5/6 inhibitor bisindolylmaleimide XI.

open access: yes, 2015
Light response measurements were made pre-treatment, post-DMSO carrier control treatement, and post-inhibitor treatment. Raster plots of A) 9 P8 ipRGCs treated with 100 μM inhibitor, B) 7 P8 ipRGCs treated with 200 μM inhibitor, C) 4 P30 ipRGCs treated ...
Timothy J. Sexton (754122)   +1 more
core   +1 more source

Assessing Morphology of ipRGCs After Traumatic Brain Injury [PDF]

open access: yes, 2020
ipRGCs are retinal ganglion cells that project to visual processing centers of the brain for nonimage forming visual functions. The relation of ipRGCs to tramatic brain injury (TBI) is emerging as data has been published describing ipRGC functional ...
Smith, Matt, Foresi, Brian
core  

A retinal contribution to opioid-induced sleep disorders?

open access: yesFrontiers in Neuroscience, 2022
Chronic opioid use is linked to persistent and severe sleep/wake disturbances in patients. These opioid-related sleep problems increase risk for developing opioid dependence, mood disorders and in turn overdose in chronic pain patients receiving opioid ...
Nikolas Bergum   +3 more
doaj   +1 more source

The Ecology of Human Sleep (EcoSleep) Cohort Study: Protocol for a longitudinal repeated measurement burst design study to assess the relationship between sleep determinants and outcomes under real‐world conditions across time of year

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The interplay of daily life factors, including mood, physical activity, or light exposure, influences sleep architecture and quality. Laboratory‐based studies often isolate these determinants to establish causality, thereby sacrificing ecological validity.
Anna M. Biller   +8 more
wiley   +1 more source

Investigating the morphology of ipRGCs in control vs. glaucomatous retinas [PDF]

open access: yes, 2020
Glaucoma is a build-up of pressure in the eye that leads to the gradual loss of sight. The intention of this study was to investigate how glaucoma affects intrinsically photosensitive Retinal Ganglion Cells (ipRGCs).
Cook, Samantha
core  

Subjective time expansion with increased stimulation of intrinsically photosensitive retinal ganglion cells

open access: yesScientific Reports, 2018
Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain photoreceptors that are especially sensitive to blue light. Nevertheless, how blue light and ipRGCs affect time perception remains unsolved. We used the oddball paradigm and manipulated
Pei-Ling Yang   +4 more
doaj   +1 more source

Central melanopsin projections in the diurnal rodent, Arvicanthis niloticus

open access: yesFrontiers in Neuroanatomy, 2015
The direct effects of photic stimuli on behavior are very different in diurnal and nocturnal species, as light stimulates an increase in activity in the former and a decrease in the latter. Studies of nocturnal mice have implicated a select population of
Jennifer Lou Langel   +6 more
doaj   +1 more source

The effects of spectrum, irradiance, and duration of exposure on light‐induced melatonin suppression in healthy adults

open access: yesPhotochemistry and Photobiology, EarlyView.
The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena   +4 more
wiley   +1 more source

ON-bipolar cell input to M1 ipRGCs may be either direct or indirect.

open access: yes, 2013
L-AP4 acts at the mGluR6 receptor located on the dendrites of ON-bipolar cells. L-AP4 inhibition of light-induced Fos expression in M1 ipRGCs establishes that this functional channel provides synaptic drive to M1 ipRGCs.
Malcolm D. Ogilvie (373840)   +3 more
core   +1 more source

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