Results 51 to 60 of about 3,566 (193)
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki +7 more
wiley +1 more source
Treatment of ipRGCs with the GRK2/5/6 inhibitor bisindolylmaleimide XI.
Light response measurements were made pre-treatment, post-DMSO carrier control treatement, and post-inhibitor treatment. Raster plots of A) 9 P8 ipRGCs treated with 100 μM inhibitor, B) 7 P8 ipRGCs treated with 200 μM inhibitor, C) 4 P30 ipRGCs treated ...
Timothy J. Sexton (754122) +1 more
core +1 more source
Assessing Morphology of ipRGCs After Traumatic Brain Injury [PDF]
ipRGCs are retinal ganglion cells that project to visual processing centers of the brain for nonimage forming visual functions. The relation of ipRGCs to tramatic brain injury (TBI) is emerging as data has been published describing ipRGC functional ...
Smith, Matt, Foresi, Brian
core
A retinal contribution to opioid-induced sleep disorders?
Chronic opioid use is linked to persistent and severe sleep/wake disturbances in patients. These opioid-related sleep problems increase risk for developing opioid dependence, mood disorders and in turn overdose in chronic pain patients receiving opioid ...
Nikolas Bergum +3 more
doaj +1 more source
Summary The interplay of daily life factors, including mood, physical activity, or light exposure, influences sleep architecture and quality. Laboratory‐based studies often isolate these determinants to establish causality, thereby sacrificing ecological validity.
Anna M. Biller +8 more
wiley +1 more source
Investigating the morphology of ipRGCs in control vs. glaucomatous retinas [PDF]
Glaucoma is a build-up of pressure in the eye that leads to the gradual loss of sight. The intention of this study was to investigate how glaucoma affects intrinsically photosensitive Retinal Ganglion Cells (ipRGCs).
Cook, Samantha
core
Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain photoreceptors that are especially sensitive to blue light. Nevertheless, how blue light and ipRGCs affect time perception remains unsolved. We used the oddball paradigm and manipulated
Pei-Ling Yang +4 more
doaj +1 more source
Central melanopsin projections in the diurnal rodent, Arvicanthis niloticus
The direct effects of photic stimuli on behavior are very different in diurnal and nocturnal species, as light stimulates an increase in activity in the former and a decrease in the latter. Studies of nocturnal mice have implicated a select population of
Jennifer Lou Langel +6 more
doaj +1 more source
The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena +4 more
wiley +1 more source
ON-bipolar cell input to M1 ipRGCs may be either direct or indirect.
L-AP4 acts at the mGluR6 receptor located on the dendrites of ON-bipolar cells. L-AP4 inhibition of light-induced Fos expression in M1 ipRGCs establishes that this functional channel provides synaptic drive to M1 ipRGCs.
Malcolm D. Ogilvie (373840) +3 more
core +1 more source

