Results 41 to 50 of about 3,566 (193)

Co-expression of two subtypes of melatonin receptor on rat M1-type intrinsically photosensitive retinal ganglion cells.

open access: yesPLoS ONE, 2015
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are involved in circadian and other non-image forming visual responses. An open question is whether the activity of these neurons may also be under the regulation mediated by the neurohormone ...
Wen-Long Sheng   +4 more
doaj   +1 more source

Brightness perception under photopic conditions: experiments and modeling with contributions of S-cone and ipRGC [PDF]

open access: yesScientific Reports, 2023
Abstract In 1924, the CIE published and standardized the photopic luminous efficiency function. Based on the standardized curve, luminous flux in lumens, luminance in cd/m $$^2$$
Khanh, Tran Quoc   +3 more
openaire   +3 more sources

Expression of different RGC markers in retinal ipRGCs of Arvicanthis.

open access: yes, 2013
Double immunolabeling of retina wholemounts with an anti-melanopsin antibody (left column) and a specific RGC marker (middle column). The right column depicts the superposition of the two previous pictures (melanopsin-positive ipRGCs in magenta, specific
Diana Karnas (287976)   +4 more
core   +1 more source

Light-induced Fos expression in ipRGCs.

open access: yes, 2013
*Fos expression in melanopsin ipRGCs.**Fos expression in β-galactoside ipRGCs. n = 3 animals for each group except Dark tau-lacZ+/+ where n = 2 animals.Animals were killed three h after light onset or at the same time but in the dark.
Malcolm D. Ogilvie (373840)   +3 more
core   +1 more source

The Retinal Basis of Light Aversion in Neonatal Mice [PDF]

open access: yes, 2022
Aversive responses to bright light (photoaversion) require signaling from the eye to the brain. Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) encode absolute light intensity and are thought to provide the light ...
Caval Holme, Franklin S.   +23 more
core   +1 more source

The ipRGC‐Driven Pupil Response with Light Exposure, Refractive Error, and Sleep [PDF]

open access: yesOptometry and Vision Science, 2018
Supplemental digital content is available in the text. SIGNIFICANCE We investigated links between the intrinsically photosensitive retinal ganglion cells, light exposure, refractive error, and sleep.
Kaleb S, Abbott   +2 more
openaire   +2 more sources

Monochromatic Pupillometry in Unilateral Glaucoma Discloses no Adaptive Changes Subserved by the ipRGCs [PDF]

open access: yesFrontiers in Neurology, 2014
To detect signs of a possible adaptive mechanism of the intrinsically photosensitive ganglion cells in unilateral glaucoma.Eleven patients with unilateral glaucoma, classified by automated perimetry (glaucoma: mean deviation
Nissen, C.   +6 more
openaire   +5 more sources

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

open access: yesiNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin   +10 more
wiley   +1 more source

Physiological heterogeneity of ipRGCs in newborn Arvicanthis retinas.

open access: yes, 2013
Light evoked responses of the three ipRGC types to 30 s stimuli (505 nm, full-field illumination) of increasing intensity recorded from a P0 Arvicanthis retina. Left column shows representative examples of spike trains recorded with multielectrode arrays.
Diana Karnas (287976)   +4 more
core   +1 more source

Tenm3 is very weakly expressed by Pou4f2-negative ipRGCs.

open access: yes, 2023
(A) Tenm3 expression is very weak in P5 Pou4f2-negative ipRGCs (dotted white circles, arrows) and higher in Pou4f2-positive ipRGCs (dotted white circles, no arrows).
Samer Hattar (58207)   +6 more
core   +1 more source

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