Results 31 to 40 of about 3,566 (193)

Selective amplification of ipRGC signals accounts for interictal photophobia in migraine [PDF]

open access: yesProceedings of the National Academy of Sciences, 2020
Abstract Second only to headache, photophobia is the most debilitating symptom reported by people with migraine. While the melanopsin-containing, intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to play a role, how cone and melanopsin signals are integrated in this pathway to produce visual discomfort is poorly ...
McAdams, Harrison   +6 more
openaire   +2 more sources

Intrinsically Photosensitive Retinal Ganglion Cells of the Human Retina

open access: yesFrontiers in Neurology, 2021
Light profoundly affects our mental and physical health. In particular, light, when not delivered at the appropriate time, may have detrimental effects.
Ludovic S. Mure, Ludovic S. Mure
doaj   +1 more source

The retinal ipRGC-preoptic circuit mediates the acute effect of light on sleep [PDF]

open access: yesNature Communications, 2021
Abstract Light regulates daily sleep rhythms by a neural circuit that connects intrinsically photosensitive retinal ganglion cells (ipRGCs) to the circadian pacemaker, the suprachiasmatic nucleus. Light, however, also acutely affects sleep in a circadian-independent manner.
Ze Zhang   +3 more
openaire   +3 more sources

A melanopsin ganglion cell subtype forms a dorsal retinal mosaic projecting to the supraoptic nucleus

open access: yesNature Communications, 2023
In addition to rod and cone photoreceptors, the mammalian retina contains intrinsically photosensitive retinal ganglion cells (ipRGCs). Here the authors identify a population of ipRGCs that encode ventral vision.
Michael H. Berry   +10 more
doaj   +1 more source

M1 Intrinsically Photosensitive Retinal Ganglion Cells Integrate Rod and Melanopsin Inputs to Signal in Low Light

open access: yesCell Reports, 2019
Summary: Light influences various behaviors and physiological processes that occur outside of our conscious perception, including circadian photoentrainment, sleep, and even learning and mood.
Seul Ki Lee   +2 more
doaj   +1 more source

Intrinsic photosensitive retinal ganglion cells in the diurnal rodent, Arvicanthis ansorgei.

open access: yesPLoS ONE, 2013
Intrinsically photosensitive retinal ganglion cells (ipRGCs) represent a new class of photoreceptors which support a variety of non-image forming physiological functions, such as circadian photoentrainment, pupillary light reflex and masking responses to
Diana Karnas   +4 more
doaj   +1 more source

A new method to quantify the human visual threshold from melanopsin sensitive ganglion cells

open access: yesFrontiers in Cellular Neuroscience, 2023
Traditional photoreceptors utilize the chromophore retinal to absorb light coupled with a unique opsin protein to specify receptor spectral sensitivity.
Jeff Rabin   +7 more
doaj   +1 more source

Endogenous opioid signaling in the retina modulates sleep/wake activity in mice

open access: yesNeurobiology of Sleep and Circadian Rhythms, 2022
Circadian sleep/wake rhythms are synchronized to environmental light/dark cycles in a process known as photoentrainment. We have previously shown that activation of β-endorphin-preferring μ-opioid receptors (MORs) inhibits the light-evoked firing of ...
Casey-Tyler Berezin   +5 more
doaj   +1 more source

Effects of pupil size as manipulated through ipRGC activation on visual processing

open access: yesNeuroImage, 2023
Experimental resources for Mathôt et al.
Sebastiaan Mathôt   +5 more
openaire   +3 more sources

Development of melanopsin-based irradiance detecting circuitry

open access: yesNeural Development, 2011
Background Most retinal ganglion cells (RGCs) convey contrast and motion information to visual brain centers. Approximately 2% of RGCs are intrinsically photosensitive (ipRGCs), express melanopsin and are necessary for light to modulate specific ...
Morhardt Duncan   +6 more
doaj   +1 more source

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