Results 41 to 50 of about 1,216 (154)

Development of a red-shifted photosensitizer for near-infrared photoimmunotherapy of cancer

Journal of Photochemistry and Photobiology
Near-infrared photoimmunotherapy (NIR-PIT) is a recently described method for cancer treatment that utilizes an antibody-conjugated phthalocyanine photosensitizer and NIR light. In NIR-PIT, light of 690 nm wavelength is used to activate a photosensitizer,
Yuto Goto, Kanta Ando, Hideo Takakura, Kohei Nakajima, Masato Kobayashi, Osamu Inanami, Tetsuya Taketsugu, Mikako Ogawa   +7 more
doaj   +2 more sources

Severe drug-induced interstitial lung disease after photoimmunotherapy with cetuximab–sarotalocan sodium in a patient with oropharyngeal cancer: A case report [PDF]

Respiratory Medicine Case Reports
Background: Photoimmunotherapy (PIT) using cetuximab–sarotalocan sodium (CS) is a novel therapy for unresectable or locally recurrent head and neck squamous cell carcinoma (HNSCC).
Sho Takuma, Masato Karayama, Risa Suzuki, Koichi Miyashita, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Takafumi Suda   +12 more
doaj   +2 more sources

Targeted Elimination of Influenza Virus and Infected Cells with Near-Infrared Antiviral Photoimmunotherapy (NIR-AVPIT) [PDF]

Pharmaceutics
Background: Seasonal influenza causes significant morbidity and mortality each year. Since viruses can easily acquire drug-resistant mutations, it is necessary to develop new antiviral strategies with different targets.
Terumi Mizukoshi, Koichiro Tateishi, Mizuki Tokusanai, Yoshiyuki Yoshinaka, Aisaku Yamamoto, Naoki Yamamoto, Norio Yamamoto   +6 more
doaj   +2 more sources

Tissue factor targeted near-infrared photoimmunotherapy: a versatile therapeutic approach for malignancies [PDF]

Cancer Immunology, Immunotherapy
Tissue factor (TF) is a cell surface protein that plays a role in blood clotting but is also commonly expressed in many cancers. Recent research implicated TF in cancer proliferation, metastasis, angiogenesis, and immune escape.
Seiichiro Takao, Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Shuhei Okuyama, Makoto Kano, Hiroshi Yamamoto, Motofumi Suzuki, Miyu Kano, Peter L. Choyke, Hisataka Kobayashi   +10 more
doaj   +2 more sources

Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials

EBioMedicine, 2021
Background: near-infrared photoimmunotherapy (NIR-PIT) is a cancer treatment that uses antibody-photoabsorber (IRDye700DX, IR700) conjugates (APCs) which bind to target cells and are photoactivated by NIR light inducing rapid necrotic cell death. NIR-PIT
Ryuhei Okada, Aki Furusawa, Daniel W. Vermeer, Fuyuki Inagaki, Hiroaki Wakiyama, Takuya Kato, Tadanobu Nagaya, Peter L. Choyke, William C. Spanos, Clint T. Allen, Hisataka Kobayashi   +10 more
doaj   +1 more source

Trastuzumab‐based near‐infrared photoimmunotherapy in xenograft mouse of breast cancer

Cancer Medicine, 2023
Near‐infrared photoimmunotherapy (NIR‐PIT) is a novel form of cancer treatment using conjugates of antibody against overexpressed antigens in cancers and photoabsorber IRDye700DX.
Susumu Yamashita, Miho Kojima, Nobuhiko Onda, Toshinori Yoshida, Makoto Shibutani   +4 more
doaj   +1 more source

Comparison of low-molecular-weight ligand and whole antibody in prostate-specific membrane antigen targeted near-infrared photoimmunotherapy [PDF]

, 2021
Near-infrared photoimmunotherapy (NIR-PIT) is a cancer phototherapy that uses antibody-IR700 conjugate (AbIR700) and NIR light. Ab-IR700 forms aggregates on the plasma membranes of targeted cancer cells after light exposure, inducing lethal physical ...
Terada, Kazuki, Ogawa, Mikako, Miyazaki, Fuka, Nakajima, Kohei, Suzuki, Motofumi, Takakura, Hideo   +5 more
core   +1 more source

Development of near-infrared imaging agents for detection of junction adhesion molecule-A protein

Translational Oncology, 2021
Introduction: Prostate and breast cancer are the most prevalent primary malignant human tumors globally. Prostatectomy and breast conservative surgery remain the most common definitive treatment option for the >500,000 men and women newly diagnosed with ...
E. Walker, S.M. Turaga, X. Wang, R. Gopalakrishnan, S. Shukla, J.P. Basilion, J.D. Lathia   +6 more
doaj   +1 more source

Correction: Sioud et al. Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Monolayer and Multicellular Tumor Spheroid Models. Cancers 2021, 13, 3356 [PDF]

Cancers, 2021
The authors wish to make the following corrections to this paper [...]
Mouldy Sioud, Petras Juzenas, Qindong Zhang, Andrius Kleinauskas, Qian Peng   +4 more
openaire   +1 more source

Efficacy of EGFR Targeting IR700-Related Photoimmunotherapy in Preventing Growth of Cancer Cells—A Systematic Review

Cancer Management and Research
Junxin Huang,1,* Xiaoqian Liu,2,* Terry Hao Yu Qin,2,* Xiaoping Duan,3 Penghui Wang,4 Kaikai Guo,5 Wan Mokhzani Wan Mokhter,3 Zaidi Zakaria1 1Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health ...
Huang J, Liu X, Qin THY, Duan X, Wang P, Guo K, Wan Mokhter WM, Zakaria Z   +7 more
doaj   +1 more source