Results 61 to 70 of about 1,216 (154)
Viruses, 2022 Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus, causes adult T-cell leukemia-lymphoma, HTLV-1 associated myelopathy/tropical spastic paraparesis, and HTLV-1 uveitis.
Yasuyoshi Hatayama +13 more
doaj +1 more source
Light-induced cell death by cell-bound anti-CEA-IR700.
, 2015 BxPC-3 cells were incubated with anti-CEA-IR700 conjugate (10 μg/ml). Rapid cell killing was observed with a dose of 32 J/cm2 of 690 nm near-infrared light (blue circles), whereas only little cell killing occurred without illumination (green triangles ...
Yukihiko Hiroshima (568068) +9 more
core +1 more source
Recent Studies in Photodynamic Therapy for Cancer Treatment: From Basic Research to Clinical Trials
Pharmaceutics, 2023 Photodynamic therapy (PDT) is an emerging and less invasive treatment modality for various types of cancer. This review provides an overview of recent trends in PDT research, ranging from basic research to ongoing clinical trials, focusing on different ...
Tae Eun Kim, Ji-Eun Chang
doaj +1 more source
VIEW, EarlyView.Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf +5 more
wiley +1 more source
Quantitative evaluation of malignant gliomas damage induced by photoactivation of IR700 dye
, 2019 The processes involved in malignant gliomas damage were quantitatively evaluated by microscopy. The near-infrared fluorescent dye IR700 that is conjugated to an anti-CD133 antibody (IR700-CD133) specifically targets malignant gliomas (U87MG) and stem ...
Morito Sakuma (1723891) +2 more
core +1 more source
British Journal of Pharmacology, EarlyView.Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka +3 more
wiley +1 more source
Regulatory approval of photoimmunotherapy: photodynamic therapy that induces immunogenic cell death
OncoImmunology, 2020 In September 2020, the Japanese government approved cetuximab saratolacan (previously known as RM-1929, commercial name: Akalux) for the treatment of unresectable locally advanced or recurrent head and neck cancer.
Lígia C. Gomes-da-Silva +2 more
doaj +1 more source
Photoimmunotherapy: A New Paradigm in Solid Tumor Immunotherapy
Cancer Control, 2022 In recent years, the incidence of cancer has been increasing worldwide. Conventional cancer treatments include surgery, chemotherapy, and radiation, which mostly kill tumor cells at the expense of normal and immune cells.
Zheng Peng PhD +2 more
doaj +1 more source
Treatment of Pancreatic Cancer Using Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts in Combination with Anticancer Chemotherapeutic Drug. [PDF]
Cancers (Basel)Background: Pancreatic ductal adenocarcinoma (PDAC), which has a poor prognosis, involves an overabundance of fibroblasts and extracellular matrix. Cancer-associated fibroblasts (CAFs) are critical for providing structural support by secreting soluble ...
Yonemura H +5 more
europepmc +2 more sources
The FEBS Journal, EarlyView.Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester +11 more
wiley +1 more source