Results 81 to 90 of about 1,216 (154)
Photoimmunotherapy of gastric cancer peritoneal carcinomatosis in a mouse model. [PDF]
PLoS ONE, 2014 Photoimmunotherapy (PIT) is a new cancer treatment that combines the specificity of antibodies for targeting tumors with the toxicity induced by photosensitizers after exposure to near infrared (NIR) light.
Kazuhide Sato +2 more
doaj +1 more source
Advanced Therapeutics, Volume 9, Issue 4, April 2026.Advanced ovarian cancer has a poor prognosis largely due to chemoresistance driven by ATP‐binding cassette (ABC) drug efflux transporters, especially P‐glycoprotein (P‐gp, or ABCB1). While photodynamic therapy (PDT) with FDA‐approved benzoporphyrin derivative (BPD) can inhibit ABC transporters, BPD alone lacks cancer selectivity.
Kathryn L. McNaughton +6 more
wiley +1 more source
HER2 targeting near‐infrared photoimmunotherapy for a CDDP‐resistant small‐cell lung cancer
Cancer Medicine, 2021 Background Human epidermal growth factor receptor 2 (HER2) is tyrosine kinase receptor that belongs to the ErbB family and is overexpressed on the membrane surface of various cancer cells, including small cell lung cancer (SCLC); however, no HER2 ...
Kazuomi Takahashi +8 more
doaj +1 more source
Photonics, 2022 Cylindrical light diffusers (CLDs) are often employed for the treatment of large tumors by interstitial photodynamic therapy (iPDT) and photoimmunotherapy (PIT), which involves careful treatment planning to maximize therapeutic dose coverage while ...
Aurélien Gregor +2 more
doaj +1 more source
Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.Tumour‐targeted fluorescence‐guided surgery (Ttfgs) enhances intraoperative precision in gastrointestinal cancer treatment. Translation of (Ttfgs) into clinical practice is limited by heterogeneity, regulatory hurdles, biomarker variability and absence of phase III trials.
Aaya Darai +7 more
wiley +1 more source
The Effect of Antibody Fragments on CD25 Targeted Regulatory T Cell Near-Infrared Photoimmunotherapy
, 2019 Regulatory T (Treg) cells play a major role in immune suppression permitting tumors to evade immune surveillance. Depletion of intratumoral Treg cells can result in tumor regression. However, systemic depletion of Tregs may also induce autoimmune adverse
Ryuhei Okada (7419425) +15 more
core +1 more source
Small Structures, Volume 7, Issue 3, March 2026.Multidrug resistance in breast cancer constitutes a major therapeutic obstacle. This review examines light‐activated nanoplatforms combining photothermal and photodynamic therapies to overcome this challenge. Through rational design, these systems enable spatiotemporal control, enhanced tumor targeting, and synergistic antitumor efficacy.
Xianghui Duan +9 more
wiley +1 more source
Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy
Advanced Science, Volume 13, Issue 10, 18 February 2026.This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao +6 more
wiley +1 more source
A Novel Theranostic Combination of Near-infrared Fluorescence Imaging and Laser Irradiation Targeting c-KIT for Gastrointestinal Stromal Tumors [PDF]
, 2018 It is difficult to distinguish gastrointestinal stromal tumors (GISTs) from other types of submucosal tumors under conventional gastrointestinal endoscopy.
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core
, 2017 Pan IR700 mediated PIT has no effect on normal urothelial cell line, UPS54.
Reema Railkar (4847722) +10 more
core +1 more source