Results 91 to 100 of about 2,411 (155)

Protocol to study the role of endogenously produced itaconate using CRISPR-Cas9 technology in THP-1 cells. [PDF]

STAR Protoc
Bourner LA, Acken KA, Long H, Chung LA, Roth KD, Dorsey FC.   +5 more
europepmc   +1 more source

Chronic macrophage activation derails muscle repair by disrupting mannose-receptor-linked plasticity revealed by endogenous irg1/acod1 tracking. [PDF]

Nat Commun
Spencer CG, Hamilton M, Bedsole E, Wei YN, Rojas AM, Burciu A, Zhu J, Sabin KZ, Shiau CE.   +8 more
europepmc   +1 more source

Mesenchymal Stromal Cells in Immunometabolic Regulation: A Review of Itaconate-Mediated Mechanisms. [PDF]

Stem Cell Rev Rep
Amon RLR, Giannini GT, de Freitas S, Fock RA.   +3 more
europepmc   +1 more source

Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation. [PDF]

Redox Biol
Zhong Z, Wang S, Ren Q, Jiao X, Xu L, Dong X, Li N, Guan H, Chu R, Yuan M, Liu J, Du Y, Wei K, Yan L, Wang G.   +14 more
europepmc   +1 more source

The role of glucose metabolic reprogramming in myocarditis and advances in therapeutic strategies. [PDF]

Front Cardiovasc Med
Liu X, Han B.
europepmc   +1 more source

Metabolic control of neuroinflammation: focus on itaconate and its derivatives in CNS disorders. [PDF]

Front Immunol
Wang Y, Liu S, Zhu W, Hao P, Xu J, Mai D, Chen R, Han H, Bian X, Wang B.   +9 more
europepmc   +1 more source

IL-27-Ucp2-FoxO3 axis mediating the polarization of alternatively activated macrophages and ameliorating inflammatory pain. [PDF]

Korean J Pain
Ma Y, Gan S, Zheng Y, Kang X, Zhu S.
europepmc   +1 more source

Itaconate transport across the plasma membrane and Salmonella-containing vacuole via MCT1/4 modulates macrophage antibacterial activity. [PDF]

Nat Commun
Meng Q, Li C, Cai Y, Chen Y, Chen X, Wang X, Zhang B, Zhang Y, Liu F, Chen M.   +9 more
europepmc   +1 more source

Immune-responsive gene 1: The mitochondrial key to Th17 cell pathogenicity in CNS autoimmunity. [PDF]

Proc Natl Acad Sci U S A
Nematullah M, Fatma M, Zhou G, Prajapati B, Rashid F, Ayasolla K, Ahmed ME, She R, Mir S, Zahoor I, Hoda N, Rattan R, Giri S.   +12 more
europepmc   +1 more source

Lactobacillus johnsonii-derived extracellular vesicles modulate gut microbiota metabolites and macrophage-related immune responses against Salmonella Typhimurium infection. [PDF]

Vet Res
Wu Y, Chen K, Hu T, Luo Y, Zhang Y, Yang G, Wang J, Zhu Y.   +7 more
europepmc   +1 more source