Results 91 to 100 of about 6,991 (174)

Irisin and Bone: From Preclinical Studies to the Evaluation of Its Circulating Levels in Different Populations of Human Subjects

Cells, 2019
Almost four years after the discovery of the anabolic action of irisin on bone in mice, ample clinical evidence is emerging in support of its additional physiological relevance in human bone.
Graziana Colaianni, Lorenzo Sanesi, Giuseppina Storlino, Giacomina Brunetti, Silvia Colucci, Maria Grano   +5 more
doaj   +1 more source

Comparison of irisin hormone expression between thyroid cancer tissues and oncocytic variant cells

Cancer Management and Research, 2019
Kader Ugur,1 Suleyman Aydin,2 Tuncay Kuloglu,3 Gokhan Artas,4 Mehmet Ali Kocdor,5 İbrahim Sahin,2,6 Meltem Yardim,2 İbrahim Hanefi Ozercan41Department of Endocrinology and Metabolism Disease, School of Medicine, Firat University, Elazig, Turkey ...
Ugur K, Aydin S, Kuloglu T, Artas G, Kocdor MA, Sahin İ, Yardim M, Hanifi Ozercan I   +7 more
doaj  

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

Advanced Science
Pulmonary vascular remodeling, which current therapeutic targets fail to alleviate disease severity, plays a key role in pulmonary arterial hypertension (PAH).
Na Sun, Yong‐Bing Wang, Jing Huang, Run‐Wei Deng, Hui‐Yu He, Lei Gao, Xuan Gao, You‐Li Fan, Yan Cong, Yao‐Lei Guo, Yi‐Qiang Chen, Gui‐Jia Wang, Shao‐Hong Fang, Xia Gu, Bo Yu, Bing‐Xiang Wu   +15 more
doaj   +1 more source

Irisin inhibits microglial senescence via TFAM-mediated mitochondrial metabolism in a mouse model of tauopathy

Immunity & Ageing
Background The accumulation of senescent microglia has been highlighted as a critical contributor to the progression of tauopathies. Irisin, a muscle-derived hormone produced by the proteolytic cleavage of Fibronectin-domain III containing 5 (FNDC5 ...
Cailin Wang, Xiufeng Wang, Shangqi Sun, Yanmin Chang, Piaopiao Lian, Hongxiu Guo, Siyi Zheng, Rong Ma, Gang Li   +8 more
doaj   +1 more source

Irisin alleviated sepsis via enhancing macrophage phagocytosis and reducing inflammation levels

Frontiers in Immunology
BackgroundThe treatment of sepsis relies on antibiotics following infection; however, the emergence of resistant bacteria necessitates the development of new therapeutic agents.
Zeen Gong, Yunyan Ji, Haiyang Wu, Linli Xue, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Juan Wang, Yanjun Dong, Haidong Wang   +10 more
doaj   +1 more source

Irisin [PDF]

, 2020
openaire   +1 more source

The relationship between serum irisin levels and renal function in patients with type 2 diabetes mellitus [PDF]

Caspian Journal of Internal Medicine
Background: Irisin, a myokine implicated in metabolic hemostasis, have been investigated in relation to type 2 diabetes mellitus (T2DM), yet findings on its serum levels and association with diabetic complications such as nephropathy remain inconsistent.
Robab Beigom Aboutorabi, Golrokh Hariri, Zahra Mazloum Khorasani, Hassan Mehrad-Majd   +3 more
doaj  

Issue Information

Experimental Physiology, Volume 111, Issue 3, Page 1554-1560, 1 March 2026.
wiley   +1 more source

Irisin‐mediated muscle‐renal crosstalk as a protective mechanism against contrast‐induced acute kidney injury via cGAS‐STING signalling inhibition

Clinical and Translational Medicine
Background Contrast‐induced acute kidney injury (CI‐AKI) continues to pose a pressing clinical challenge during invasive cardiovascular procedures due to the limited availability of preventative strategies.
Long Peng, Suhua Li, Qiang Huang, Yuxiang Sun, Juan Sun, Ting Luo, Yanlin Wang, Zhaoyong Hu, Weiyan Lai, Hui Peng   +9 more
doaj   +1 more source

Irisin inhibits adipogenic differentiation of bone marrow mesenchymal stem cells through the SIRT1/RANBP2/FTO signaling axis and protects against osteoporosis. [PDF]

Cell Death Discov
Chen J, Liu J, Fu Q, Xu M, Zhai X, Li L, Xu W, Wu X, Wang K, Si H.   +9 more
europepmc   +1 more source