Results 11 to 20 of about 32,260 (214)
Frontiers in Neuroscience, 2022 Friedreich’s ataxia (FRDA) is the most prevalent autosomic recessive ataxia and is associated with a severe cardiac hypertrophy and less frequently diabetes.
Beata Monfort +3 more
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Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1.
PLoS ONE, 2012 BackgroundMembers of the WhiB-like (Wbl) protein family possess iron-sulfur clusters and are implicated in the regulation of developmental processes in Actinomycetes. Mycobacterium tuberculosis possesses seven Wbl proteins.
Laura J Smith +3 more
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Description of peptide bond planarity from high-resolution neutron crystallography
Biophysics and Physicobiology, 2023 Neutron crystallography is a highly effective method for visualizing hydrogen atoms in proteins. In our recent study, we successfully determined the high-resolution (1.2 Å) neutron structure of high-potential iron-sulfur protein, refining the coordinates
Yuya Hanazono +3 more
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Down the Iron Path: Mitochondrial Iron Homeostasis and Beyond
Cells, 2021 Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent. Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate these cofactors along with iron ions into mitochondrial proteins that support ...
Jonathan V. Dietz +2 more
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Cluster and fold stability of E. coli ISC-type ferredoxin.
PLoS ONE, 2013 Iron-sulfur clusters are essential protein prosthetic groups that provide their redox potential to several different metabolic pathways. Formation of iron-sulfur clusters is assisted by a specialised machine that comprises, among other proteins, a ...
Robert Yan +6 more
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Mechanism of Iron–Sulfur Cluster Assembly: In the Intimacy of Iron and Sulfur Encounter
Inorganics, 2020 Iron–sulfur (Fe–S) clusters are protein cofactors of a multitude of enzymes performing essential biological functions. Specialized multi-protein machineries present in all types of organisms support their biosynthesis.
Batoul Srour +3 more
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Structural Basis of RICs Iron Donation for Iron-Sulfur Cluster Biogenesis
Frontiers in Microbiology, 2021 Escherichia coli YtfE is a di-iron protein of the widespread Repair of Iron Centers proteins (RIC) family that has the capacity to donate iron, which is a crucial component of the biogenesis of the ubiquitous family of iron-sulfur proteins.
Liliana S. O. Silva +4 more
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Biomolecules, 2021 Maintaining iron homeostasis is fundamental for almost all living beings, and its deregulation correlates with severe and debilitating pathologies.
Cécilia Hognon +5 more
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Iron-induced changes in the proteome of Trichomonas vaginalis hydrogenosomes. [PDF]
PLoS ONE, 2013 Iron plays a crucial role in metabolism as a key component of catalytic and redox cofactors, such as heme or iron-sulfur clusters in enzymes and electron-transporting or regulatory proteins.
Neritza Campo Beltrán +7 more
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Erythropoiesis and Iron Sulfur Cluster Biogenesis
Advances in Hematology, 2010 Erythropoiesis in animals is a synchronized process of erythroid cell differentiation that depends on successful acquisition of iron. Heme synthesis depends on iron through its dependence on iron sulfur (Fe-S) cluster biogenesis.
Hong Ye, Tracey A. Rouault
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