Results 31 to 40 of about 83,013 (204)

Iron-induced changes in the proteome of Trichomonas vaginalis hydrogenosomes. [PDF]

PLoS ONE, 2013
Iron plays a crucial role in metabolism as a key component of catalytic and redox cofactors, such as heme or iron-sulfur clusters in enzymes and electron-transporting or regulatory proteins.
Neritza Campo Beltrán, Lenka Horváthová, Petr L Jedelský, Miroslava Sedinová, Petr Rada, Michaela Marcinčiková, Ivan Hrdý, Jan Tachezy   +7 more
doaj   +1 more source

Iron-sulfur cluster-dependent enzymes and molybdenum-dependent reductases in the anaerobic metabolism of human gut microbes. [PDF]

Metallomics
Zahn LE, Gannon PM, Rajakovich LJ.
europepmc   +3 more sources

Differentiated, promoter-specific response of [4Fe-4S] NsrR DNA-binding to reaction with nitric oxide [PDF]

, 2016
NsrR is an iron-sulfur cluster protein that regulates the nitric oxide (NO) stress response of many bacteria. NsrR from Streptomyces coelicolor regulates its own expression and that of only two other genes, hmpA1 and hmpA2, which encode HmpA enzymes ...
Crack, Jason, Hutchings, Matthew, Le Brun, Nicolas, Munnoch, John, Svistunenko, Dimitri A., Thomson, Andrew   +5 more
core   +1 more source

Erythropoiesis and Iron Sulfur Cluster Biogenesis

Advances in Hematology, 2010
Erythropoiesis in animals is a synchronized process of erythroid cell differentiation that depends on successful acquisition of iron. Heme synthesis depends on iron through its dependence on iron sulfur (Fe-S) cluster biogenesis.
Hong Ye, Tracey A. Rouault
doaj   +1 more source

Glutaredoxin GRXS17 associates with the cytosolic iron-sulfur cluster assembly pathway [PDF]

, 2016
Cytosolic monothiol glutaredoxins (GRXs) are required in iron-sulfur (Fe-S) cluster delivery and iron sensing in yeast and mammals. In plants, it is unclear whether they have similar functions.
Cammue, Bruno PA, De Clercq, Rebecca, De Coninck, Barbara, De Jaeger, Geert, Fernie, Alisdair R, Gevaert, Kris, Goossens, Alain, Iñigo, Sabrina, Klassen, Roland, Le Gall, Sabine, Leidel, Sebastian A, Nagels Durand, Astrid, Pauwels, Laurens, Ritter Traub, Andrés, Schaffrath, Raffael, Termathe, Martin, Tohge, Takayuki, Van Leene, Jelle, Van Lijsebettens, Maria   +18 more
core   +2 more sources

The Molecular Bases of the Dual Regulation of Bacterial Iron Sulfur Cluster Biogenesis by CyaY and IscX

Frontiers in Molecular Biosciences, 2018
IscX (or YfhJ) is a protein of unknown function which takes part in the iron-sulfur cluster assembly machinery, a highly specialized and essential metabolic pathway. IscX binds to iron with low affinity and interacts with IscS, the desulfurase central to
Salvatore Adinolfi, Rita Puglisi, Jason C. Crack, Clara Iannuzzi, Clara Iannuzzi, Fabrizio Dal Piaz, Petr V. Konarev, Petr V. Konarev, Dmitri I. Svergun, Stephen Martin, Nick E. Le Brun, Annalisa Pastore, Annalisa Pastore   +12 more
doaj   +1 more source

Escherichia coli RIC is able to donate iron to iron-sulfur clusters. [PDF]

PLoS ONE, 2014
Escherichia coli RIC (Repair of Iron Centers) is a diiron protein previously reported to be involved in the repair of iron-sulfur proteins damaged by oxidative or nitrosative stresses, and proposed to act as an iron donor.
Lígia S Nobre, Ricardo Garcia-Serres, Smilja Todorovic, Peter Hildebrandt, Miguel Teixeira, Jean-Marc Latour, Lígia M Saraiva   +6 more
doaj   +1 more source

Sensing iron availability via the fragile [4Fe-4S] cluster of the bacterial transcriptional repressor RirA [PDF]

, 2017
Rhizobial iron regulator A (RirA) is a global regulator of iron homeostasis in many nitrogen-fixing Rhizobia and related species of α-proteobacteria.
Agar, Agarwalla, Anderegg, Andrews, Bandyopadhyay, Beinert, Beringer, Bhubhanil, Busch, Carter, Chao, Crack, Crack, Crack, Crack, Crack, Crack, Crack, D'Aquino, Ding, Downie, Figurski, Fleischhacker, Gibbs, Giel, Giel, Imlay, Isabella, Johnson, Johnston, Kay, Keon, Kibbe, Kommineni, Kounosu, Laganowsky, Lee, Martell, Miller, Munnoch, Nesbit, Ngok-Ngam, Nicholas, O'Brian, Pohl, Qi, Rajagopalan, Rudolph, Sambrook, Sanakis, Santos, Schwartz, Shepard, Sievers, Singleton, Svistunenko, Todd, Todd, Todd, Viguier, Volbeda, Wexler, Wexler, White, Yeo, Yeoman, Yeoman, Zhang   +67 more
core   +1 more source

Probing the coordination and function of Fe4S4 modules in nitrogenase assembly protein NifB

Nature Communications, 2018
NifB is a key enzyme in the biosynthesis pathway of the nitrogenase FeMo cofactor. Here, the authors investigate the maturation of its iron-sulfur clusters by EPR and biochemical analyses, showing how individual precursor clusters participate in the ...
Lee A. Rettberg, Jarett Wilcoxen, Chi Chung Lee, Martin T. Stiebritz, Kazuki Tanifuji, R. David Britt, Yilin Hu   +6 more
doaj   +1 more source

Pichia pastoris Fep1 is a [2Fe-2S] protein with a Zn finger that displays an unusual oxygen-dependent role in cluster binding [PDF]

, 2016
Fep1, the iron-responsive GATA factor from the methylotrophic yeast Pichia pastoris, has been characterised both in vivo and in vitro. This protein has two Cys(2)-Cys(2) type zinc fingers and a set of four conserved cysteines arranged in a Cys-X-5-Cys-X ...
Battistoni, Andrea, BONACCORSI DI PATTI, Maria Carmela, Cutone, Antimo, Giorgi, Alessandra, Howes, Barry D., Miele, Adriana Erica, Miele, Rossella, Musci, Giovanni, Smulevich, Giulietta   +8 more
core   +4 more sources