Results 11 to 20 of about 20,621 (305)
Role of Flavonoids in the Treatment of Iron Overload
Frontiers in Cell and Developmental Biology, 2021 Iron overload, a high risk factor for many diseases, is seen in almost all human chronic and common diseases. Iron chelating agents are often used for treatment but, at present, most of these have a narrow scope of application, obvious side effects, and ...
Xiaomin Wang +6 more
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Silybin, a new iron-chelating agent
Journal of Inorganic Biochemistry, 2001 Silybin, a natural occurring flavolignan isolated from the fruits of Silibum marianum, has been reported to exert antioxidant and free radical scavenging abilities. It was suggested to act also as an iron chelator. The complexation and protonation equilibria of the ferric complex of this compound have been studied by potentiometric, spectrophotometric ...
Marco Borsari +6 more
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Ferritin iron mobilisation by chelating agents [PDF]
FEBS Letters, 1980 In a large number of eukaryotes iron is stored in a soluble non-toxic form in ferritin. The iron is deposited in the interior of an approximately spherical protein shell, predominantly as ferric oxyhydroxide (reviewed [ 1,2] ). A number of mechanisms have been proposed for ferritin iron release involving low molecular weight chelators [3,4], enzyme ...
Crichton, Robert R. +2 more
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Frontiers in Neurology, 2022 Studies have shown that iron accumulation in the brain leads to neurogenic disorders. Novel iron chelating agents such as natural remedies are useful to decrease the side effects of iron in the brain.
Mahdi AAlikhani +3 more
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Frontiers in Chemistry, 2021 Incorporating nanoparticles into devices for a wide range of applications often requires the formation of thick films, which is particularly necessary for improving magnetic power storage, microwave properties, and sensor performance.
Sara C. Mills +3 more
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A Case Study and a Brief Review on Dermatopathological Drug Reaction in Major Thalassemia [PDF]
Reviews in Clinical Medicine, 2023 Introduction: Thalassemia consists of a variety of genetic hemoglobinopathies. Thalassemia-major causes anemia in early age. Those suffering from thalassemia need frequent life-long blood transfusions to survive, resulting in iron overload in the body ...
Afshan Shirkavand +3 more
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Thalassemia and Nanotheragnostics: Advanced Approaches for Diagnosis and Treatment
Biosensors, 2023 Thalassemia is a monogenic autosomal recessive disorder caused by mutations, which lead to abnormal or reduced production of hemoglobin. Ineffective erythropoiesis, hemolysis, hepcidin suppression, and iron overload are common manifestations that vary ...
Zahra Tariq +4 more
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Points from Letters: An oral iron-chelating agent [PDF]
BMJ, 1978 Samuel Hopkins
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Frontiers in Pharmacology, 2021 Metal chelating agents are antioxidant agents, which decrease the reductive potential and stabilize the oxidized metal ion form. In this study, we evaluated the naringin capacity in chelating iron and preventing amyloid-beta plaque formation in the ...
Mehrdad Jahanshahi +3 more
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Frontiers in Neurology, 2021 Introduction: Administration of aminoglycoside (AG) antibiotics is one of the most common causes of ototoxicity. This study aimed to determine the protective effects of deferoxamine, an iron-chelating agent, on vestibulotoxicity using an intratympanic ...
Hyo-Jung Kim +3 more
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