Results 21 to 30 of about 51,265 (314)
Role of Flavonoids in the Treatment of Iron Overload
Frontiers in Cell and Developmental Biology, 2021 Iron overload, a high risk factor for many diseases, is seen in almost all human chronic and common diseases. Iron chelating agents are often used for treatment but, at present, most of these have a narrow scope of application, obvious side effects, and ...
Xiaomin Wang +6 more
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Iron-chelating agents for treating malaria
Cochrane Database of Systematic Reviews, 2003 Researchers are exploring the effects of adding treatments to the main antimalarial regimens in an attempt to reduce mortality from Plasmodium falciparum. Iron chelation is one potential chemotherapeutic adjuvant treatment. Before advocating adjunctive therapy, the effects of iron chelators in improving patient outcomes need to be examined.To assess ...
Helen Smith, Martin Meremikwu
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Defining Pathological Iron Status in Children with Thalassemia [PDF]
المجلة العراقية للصيدلة, 2022 The purpose of this review is to summarize the recent knowledge that has been gathered, allowing a better understanding of iron status in children with thalassemia.
Bashar Mustafa
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Ferritin iron mobilisation by chelating agents [PDF]
FEBS Letters, 1980 In a large number of eukaryotes iron is stored in a soluble non-toxic form in ferritin. The iron is deposited in the interior of an approximately spherical protein shell, predominantly as ferric oxyhydroxide (reviewed [ 1,2] ). A number of mechanisms have been proposed for ferritin iron release involving low molecular weight chelators [3,4], enzyme ...
Robert R. Crichton +2 more
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Frontiers in Neurology, 2022 Studies have shown that iron accumulation in the brain leads to neurogenic disorders. Novel iron chelating agents such as natural remedies are useful to decrease the side effects of iron in the brain.
Mahdi AAlikhani +3 more
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Frontiers in Chemistry, 2021 Incorporating nanoparticles into devices for a wide range of applications often requires the formation of thick films, which is particularly necessary for improving magnetic power storage, microwave properties, and sensor performance.
Sara C. Mills +3 more
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Acute iron poisoning in children: role of chelating agents. [PDF]
BMJ, 1968 With the development of the fran-chelating agents, desferriox amine and diethylenetriamine penta-acetic acid (D.T.P.A.), it was appreciated that these substances were potentially valuable in the treatment of acute iron poisoning (Rubin and Princiotto, 1960; Bannerman et.al., 1962 ; Moeschlin and Schnider, 1963; Brit. med. 7., 1963; Lancet, 1964).
D. G. D. Barr, Debbie Fraser
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A Case Study and a Brief Review on Dermatopathological Drug Reaction in Major Thalassemia [PDF]
Reviews in Clinical Medicine, 2023 Introduction: Thalassemia consists of a variety of genetic hemoglobinopathies. Thalassemia-major causes anemia in early age. Those suffering from thalassemia need frequent life-long blood transfusions to survive, resulting in iron overload in the body ...
Afshan Shirkavand +3 more
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Iron(III) chelating resins-IV. Crosslinked copolymer beads of 1-(B-acrylamidoethyl)-3-hydroxy-2-methyl-4(1H)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA) [PDF]
, 1994 Iron(III) chelating beads have been synthesized by copolymerization of 1-(ß-acrylamidoethyl)-3-hydroxy-2-methyl-4(IH)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA), and ethyleneglycol dimethacrylate (EGDMA) as the crosslinking agent.
Bantjes, A. +2 more
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Thalassemia and Nanotheragnostics: Advanced Approaches for Diagnosis and Treatment
Biosensors, 2023 Thalassemia is a monogenic autosomal recessive disorder caused by mutations, which lead to abnormal or reduced production of hemoglobin. Ineffective erythropoiesis, hemolysis, hepcidin suppression, and iron overload are common manifestations that vary ...
Zahra Tariq +4 more
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