Results 21 to 30 of about 53,287 (249)

Naringin Chelates Excessive Iron and Prevents the Formation of Amyloid-Beta Plaques in the Hippocampus of Iron-Overloaded Mice

open access: yesFrontiers in Pharmacology, 2021
Metal chelating agents are antioxidant agents, which decrease the reductive potential and stabilize the oxidized metal ion form. In this study, we evaluated the naringin capacity in chelating iron and preventing amyloid-beta plaque formation in the ...
Mehrdad Jahanshahi   +3 more
doaj   +1 more source

Iron Chelating Agents: Promising Supportive Therapies in Severe Cases of COVID-19? [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2020
Dear Editor, On December 2019, new cases of COVID-19 pneumonia were reported from Wuhan city of China that were consequences of 2019-nCoV or SARS-CoV-2 infection (1).
Parisa Ghasemiyeh   +1 more
doaj   +1 more source

Iron(III) chelating resins-IV. Crosslinked copolymer beads of 1-(B-acrylamidoethyl)-3-hydroxy-2-methyl-4(1H)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA) [PDF]

open access: yes, 1994
Iron(III) chelating beads have been synthesized by copolymerization of 1-(ß-acrylamidoethyl)-3-hydroxy-2-methyl-4(IH)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA), and ethyleneglycol dimethacrylate (EGDMA) as the crosslinking agent.
Bantjes, A.   +2 more
core   +3 more sources

Protective Effects of Deferoxamine on Vestibulotoxicity in Gentamicin-Induced Bilateral Vestibulopathy Rat Model

open access: yesFrontiers in Neurology, 2021
Introduction: Administration of aminoglycoside (AG) antibiotics is one of the most common causes of ototoxicity. This study aimed to determine the protective effects of deferoxamine, an iron-chelating agent, on vestibulotoxicity using an intratympanic ...
Hyo-Jung Kim   +3 more
doaj   +1 more source

Inhibition of Xanthomonas fragariae, Causative Agent of Angular Leaf Spot of Strawberry, through Iron Deprivation. [PDF]

open access: yes, 2016
In commercial production settings, few options exist to prevent or treat angular leaf spot (ALS) of strawberry, a disease of economic importance and caused by the bacterial pathogen Xanthomonas fragariae.
Gebben, Samantha J   +4 more
core   +2 more sources

Pharmacogenetic Study of Deferasirox, an Iron Chelating Agent [PDF]

open access: goldPLoS ONE, 2013
Abstract Abstract 2060 Transfusion associated iron overload induce systemic toxicity. Deferoxamine had been used to reduce iron induced toxicities by chelating iron but it is a short acting drug and needs parenteral administration.
Ji Won Lee   +12 more
openalex   +6 more sources

Iron-chelating agents for treating malaria

open access: yesCochrane Database of Systematic Reviews, 2003
Researchers are exploring the effects of adding treatments to the main antimalarial regimens in an attempt to reduce mortality from Plasmodium falciparum. Iron chelation is one potential chemotherapeutic adjuvant treatment. Before advocating adjunctive therapy, the effects of iron chelators in improving patient outcomes need to be examined.To assess ...
Smith, H. J., Meremikwu, M.
openaire   +5 more sources

Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions [PDF]

open access: yes, 2015
The commercial availability of combined magnetic resonance imaging (MRI)/positron emission tomography (PET) scanners for clinical use has increased demand for easily prepared agents which offer signal or contrast in both modalities.
Al-Yassiry, M.M.   +23 more
core   +2 more sources

Impact of Sappan Wood Extract as Iron Chelator Adjuvant on Iron Concentration and Macrophage Polarization in Rat Spleen [PDF]

open access: yesIranian Journal of Medical Sciences
Background: Iron accumulation in the spleen of thalassemia patients disrupts macrophage polarization, impairs immune function, and increases mortality.
Mohammad Ghozali   +6 more
doaj   +1 more source

Antioxidant and antihemolytic activities of methanol extract of Hyssopus angustifolius [PDF]

open access: yes, 2012
This study was designed to evaluate antioxidant and antihemolytic activities of Hyssopus angustifolius flower, stem and leaf methanol extracts by employing various in vitro assays.
Alinezhad, H.   +6 more
core   +3 more sources

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