Results 141 to 150 of about 910,855 (274)

Deferiprone, an iron chelator, alleviates platelet hyperactivity in patients with β-thalassaemia/HbE. [PDF]

Drugs Context, 2022
Tran NT, Sutcharitchan P, Janprasit J, Rojnuckarin P, Morales NP, Luechapudiporn R.   +5 more
europepmc   +1 more source

Profiling Hydrolysis Rates of αS1‐Casein to αS1‐I‐Casein During Cheese Ripening by Intact‐Protein Liquid Chromatography–High Resolution Mass Spectrometry

Rapid Communications in Mass Spectrometry, Volume 40, Issue 21, 15 November 2026.
ABSTRACT Rationale The proteolytic behavior of chymosins during cheese ripening impacts cheese texture, flavor, and quality. Especially, the specific hydrolysis of αS1‐casein to αS1‐I‐casein is relevant for early cheese texture development, and this activity varies between chymosin variants.
Sebastiaan Dolman, Marjolein van der Eijk, Loes Bevers, Kees Muijlwijk, Mee Loke Lim, Margriet Hendriks, Nicolas Abello, Rob van der Hoeven   +7 more
wiley   +1 more source

Use of the Iron Chelator Deferiprone to Restore Function in BAL Fluid Macrophages in Smoking and Chronic Obstructive Pulmonary Disease. [PDF]

Am J Respir Cell Mol Biol, 2023
Kim K, Zhang WZ, Kikkers SA, O'Beirne SL, Strulovici-Barel Y, Kaner RJ, Crystal RG, Cloonan SM.   +7 more
europepmc   +1 more source

The Boron–Neuron Connection: The Potential of Boron‐Containing Molecules for Treating Incurable Amyotrophic Lateral Sclerosis

ChemMedChem, Volume 21, Issue 21, 12 November 2026.
Can a single element help address the multifactorial nature of ALS? Boron‐containing compounds combine responsiveness to reactive oxygen species (ROS), neuroprotective activity, and favorable pharmacological properties, offering a distinctive framework for disease modification in a complex disease like ALS.
Nitesh Sanghai, Billy Vuong, Muhammad Shaharyar K. Afridi, Sasha Leggett, Hemin Roghzai, Geoffrey K. Tranmer   +5 more
wiley   +1 more source

Novel iron chelator SK4 demonstrates cytotoxicity in a range of tumour derived cell lines. [PDF]

Front Mol Biosci, 2022
Abdelaal G, Carter A, Panayiotides MI, Tetard D, Veuger S.   +4 more
europepmc   +1 more source

Behavior of Injection‐Molded Nylon 6 Composites With Virgin and Field‐Exposed Waste‐Recycled Blends

Polymer Composites, Volume 47, Issue 21, Page 19382-19402, 10 November 2026.
Recycling field‐exposed Nylon 6 composites for sustainable secondary applications. ABSTRACT Every year, more than 18,600 metric tonnes of glass fiber‐reinforced Nylon 6 composite waste from sucker rod guides used in downhole oil and gas applications are landfilled due to uncertainty about retained performance after prolonged service exposure.
Chundu Gyem Tamang, Allan Manalo, Paulomi (Polly) Burey, Wahid Ferdous, Tristan Shelley, Mayur Patel, Tony Chapman   +6 more
wiley   +1 more source

Anti-Inflammatory Effects of the Iron Chelator, DIBI, in Experimental Acute Lung Injury. [PDF]

Molecules, 2022
Lehmann C, Alizadeh-Tabrizi N, Hall S, Faridi S, Euodia I, Holbein B, Zhou J, Chappe V.   +7 more
europepmc   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Ferroptosis Suppression by the M6A Reader IGF2BP1 Underlies Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

Advanced Science, Volume 13, Issue 61, 3 November 2026.
IGF2BP1 promotes gemcitabine resistance in pancreatic cancer by stabilizing m6A‐modified FTH1 transcripts and protecting them in stress granules, thereby suppressing ferroptosis. Pharmacological inhibition of IGF2BP1 disrupts this protective pathway, restores ferroptotic sensitivity, and enhances gemcitabine efficacy in resistant tumors.
Ying‐Qin Zhu, Yue Huang, Jing‐Yuan Ye, Si‐Yuan Lu, Zhi‐De Liu, Ming‐Jian Ma, De‐Liang Fang, Zi‐Yi Zhao, Jin‐Zhao Xie, Jiao Chen, Xiao‐Yu Yin   +10 more
wiley   +1 more source

Novel Antidepressant-Like Properties of the Iron Chelator Deferiprone in a Mouse Model of Depression. [PDF]

Neurotherapeutics, 2022
Uzungil V, Tran H, Aitken C, Wilson C, Opazo CM, Li S, Payet JM, Mawal CH, Bush AI, Hale MW, Hannan AJ, Renoir T.   +11 more
europepmc   +1 more source