Results 81 to 90 of about 315,195 (302)
Essential metals at the host-pathogen interface : nutritional immunity and micronutrient assimilation by human fungal pathogens [PDF]
, 2015 AC and DW are supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 102549/Z/13/Z).Peer reviewedPublisher ...
Crawford, Aaron, Wilson, Duncan
core +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source
Dysregulation of iron homeostasis in airways associated with persistent preschool wheezing
Respiratory Research, 2023 Background Currently, there are no reliable clinical tools available to identify persistent asthma symptoms among preschool children with recurrent wheezing.
Zhili Wang +5 more
doaj +1 more source
The Structure and Function of Frataxin [PDF]
, 2006 Frataxin, a highly conserved protein found in prokaryotes and eukaryotes, is required for efficient regulation of cellular iron homeostasis. Humans with a frataxin deficiency have the cardio- and neurodegenerative disorder Friedreich’s ataxia, commonly ...
Bencze, Krisztina Z. +6 more
core +2 more sources
4D‐Printed Magneto‐Plasmonic Microrobots for Programmable Spatiotemporal De‐Icing
Advanced Functional Materials, EarlyView.A 4D‐printing strategy is introduced to achieve programmable de‐icing devices. By aligning gold–magnetite nanofillers within a photosensitive resin, the printed structures exhibit dual magnetic and plasmonic functionalities, enabling precise spatio‐temporal ice removal through thermoplasmonic effects.
Amélie Pérot +7 more
wiley +1 more source
Heme Oxygenase Activity Correlates with Serum Indices of Iron Homeostasis in Healthy Nonsmokers
Biomarker Insights, 2016 Heme oxygenase (HO) catalyzes the breakdown of heme to carbon monoxide, iron, and biliverdin. While the use of genetically altered animal models in investigation has established distinct associations between HO activity and systemic iron availability ...
Andrew J. Ghio, Dina M. Schreinemachers
doaj +1 more source
Iron Regulatory Proteins, Iron Responsive Elements and Iron Homeostasis [PDF]
The Journal of Nutrition, 1998 The discovery of iron regulatory proteins (IRPs) has provided a molecular framework from which to more fully understand the coordinate regulation of vertebrate iron metabolism. IRPs bind to iron responsive elements (IREs) in specific mRNAs and regulate their utilization.
R S, Eisenstein, K P, Blemings
openaire +2 more sources
Advanced Functional Materials, EarlyView.This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann +2 more
wiley +1 more source
Critical role of iron in the pathogenesis of the murine gangliosidoses
Neurobiology of Disease, 2009 Neurodegeneration is a prominent feature of the gangliosidoses, a group of lysosomal storage diseases. Here we show altered iron homeostasis in mouse models of both GM1 and GM2 gangliosidoses, which are characterized by progressive depletion of iron in ...
Mylvaganam Jeyakumar +4 more
doaj +1 more source
The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions. [PDF]
, 2013 International audienceAlthough earlier, seminal studies demonstrated that the gut per se has the intrinsic ability to regulate the rates of iron absorption, the spotlight in the past decade has been placed on the systemic regulation of iron homeostasis ...
Mastrogiannaki, Maria +2 more
core +4 more sources