Results 1 to 10 of about 17,152 (250)

DFT Insights into NHC-Catalyzed Switchable [3+4] and [3+2] Annulations of Isatin-Derived Enals and N-Sulfonyl Ketimines: Mechanism, Regio- and Stereoselectivity. [PDF]

Molecules
Yu S, Zhou W, Jiang Y, Wang H, Zhou X, Yang S.   +5 more
europepmc   +2 more sources

Tryptophan Metabolites as Mediators of Microbiota-Gut-Brain Communication: Focus on Isatin

Frontiers in Behavioral Neuroscience, 2022
Isatin (indole-2,3-dione) is an endogenous regulator, exhibiting various behavioral, biological, and pharmacological activities. Synthesis of isatin includes several crucial stages: cleavage of the tryptophan side chain and subsequent oxidation of the ...
Alexei Medvedev, Olga Buneeva
doaj   +1 more source

Was ist Isatin?? [PDF]

Journal für Praktische Chemie, 1883
H. Kolbe
openalex   +3 more sources

Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022
Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently attracted a lot of attention in medicinal chemistry. Isatin, itself,
May Mohammed Jawad Al-Mudhafar, Tagreed N-A Omar, Shayma L. Abdulhadi   +2 more
doaj   +1 more source

The impact of isatin derivatives on antibiotic production by Streptomyces hygroscopicus CH-7 [PDF]

Hemijska Industrija, 2016
The effect of isatin derivatives as a nitrogen source on antibiotic (Hexaene H-85 and Azalomycine B) production by Streptomyces hygroscopicus CH-7 was studied.
Ćirić Jovan T., Konstantinović Sandra S., Ilić Slavica B., Gojgić-Cvijović Gordana, Savić Dragiša S., Veljković Vlada B.   +5 more
doaj   +1 more source

5-(Trifluoromethoxy)isatin [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
THE TITLE COMPOUND [SYSTEMATIC NAME: 5-(trifluoro-meth-oxy)-1H-indole-2,3-dione], C9H4F3NO3, crystallized with two mol-ecules in the asymmetric unit. Inter-molecular N-H⋯O hydrogen bonds link the mol-ecules to form layers parallel to the ab plane. In addition, π-π stacking inter-actions are observed with a centroid-centroid distance of 3.721 (1) Å. The
M. Schutte, C. Pretorius, H.G. Visser, A. Roodt   +3 more
openaire   +3 more sources

Encapsulation of an anticancer drug Isatin inside a host nano-vehicle SWCNT: a molecular dynamics simulation

Scientific Reports, 2021
The use of carbon nanotubes as anticancer drug delivery cargo systems is a promising modality as they are able to perforate cellular membranes and transport the carried therapeutic molecules into the cellular components.
Maryam Zarghami Dehaghani, Farrokh Yousefi, Farzad Seidi, Babak Bagheri, Amin Hamed Mashhadzadeh, Ghasem Naderi, Amin Esmaeili, Otman Abida, Sajjad Habibzadeh, Mohammad Reza Saeb, Maksym Rybachuk   +10 more
doaj   +1 more source

Synthesis of substituted isatins [PDF]

Tetrahedron Letters, 2013
Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an alternative method for their production.
Larry L, Klein, Michael D, Tufano
openaire   +2 more sources

Estimation of isatin in spiked plasma samples using high performance liquid chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2013
An isocratic analytical method based on liquid chromatographic determination with UV detection is described for the determination of isatin in spiked plasma and in its synthetic mixture.
Alothman Zeid A., Siddiqui Masoom R., Wabaidur Saikh M.   +2 more
doaj   +1 more source

Isatin Counteracts Diethylnitrosamine/2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Male Wistar Rats by Upregulating Anti-Inflammatory, Antioxidant, and Detoxification Pathways

Antioxidants, 2022
Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers and is estimated to be the fifth most common cause of cancer-related death worldwide.
Nagwa G. Tawfik, Wafaa R. Mohamed, Hanan S. Mahmoud, Mohammed A. Alqarni, Ibrahim A. Naguib, Alzhraa M. Fahmy, Osama M. Ahmed   +6 more
doaj   +1 more source