Results 1 to 10 of about 9,186 (209)
Cytotoxicity study of some indophenines and isatin derivatives [PDF]
Bangladesh Journal of Pharmacology, 2008 Eight indophenines were synthesized for the interest of studying biological activity especially for cytotoxicity. The cytotoxicity of some indophenines and some isatin derivatives was studied by the brine shrimp lethality bioassay.
Md. Mahbubul Hoque, Md. Rabiul Islam
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DFT Insights into NHC-Catalyzed Switchable [3+4] and [3+2] Annulations of Isatin-Derived Enals and N-Sulfonyl Ketimines: Mechanism, Regio- and Stereoselectivity. [PDF]
MoleculesYu S +5 more
europepmc +2 more sources
Tryptophan Metabolites as Mediators of Microbiota-Gut-Brain Communication: Focus on Isatin
Frontiers in Behavioral Neuroscience, 2022 Isatin (indole-2,3-dione) is an endogenous regulator, exhibiting various behavioral, biological, and pharmacological activities. Synthesis of isatin includes several crucial stages: cleavage of the tryptophan side chain and subsequent oxidation of the ...
Alexei Medvedev, Olga Buneeva
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Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022 Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently attracted a lot of attention in medicinal chemistry. Isatin, itself,
May Mohammed Jawad Al-Mudhafar +2 more
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Synthesis of Isatin and its derivatives containing heterocyclic compounds
Journal of the Turkish Chemical Society, Section A: Chemistry, 2021 Isatin or 1H-indole-2,3-dione or 2,3-dioxindole is an indole derivative. Isatin and its analogs are synthetically useful substances where they may be utilized for the production of a broad range of heterocyclic molecules, which are depicting a wide reach
Pratibha MİSHRA +4 more
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The impact of isatin derivatives on antibiotic production by Streptomyces hygroscopicus CH-7 [PDF]
Hemijska Industrija, 2016 The effect of isatin derivatives as a nitrogen source on antibiotic (Hexaene H-85 and Azalomycine B) production by Streptomyces hygroscopicus CH-7 was studied.
Ćirić Jovan T. +5 more
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5-(Trifluoromethoxy)isatin [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 THE TITLE COMPOUND [SYSTEMATIC NAME: 5-(trifluoro-meth-oxy)-1H-indole-2,3-dione], C9H4F3NO3, crystallized with two mol-ecules in the asymmetric unit. Inter-molecular N-H⋯O hydrogen bonds link the mol-ecules to form layers parallel to the ab plane. In addition, π-π stacking inter-actions are observed with a centroid-centroid distance of 3.721 (1) Å. The
M. Schutte +3 more
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Scientific Reports, 2021 The use of carbon nanotubes as anticancer drug delivery cargo systems is a promising modality as they are able to perforate cellular membranes and transport the carried therapeutic molecules into the cellular components.
Maryam Zarghami Dehaghani +10 more
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Synthesis of substituted isatins [PDF]
Tetrahedron Letters, 2013 Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an alternative method for their production.
Larry L, Klein, Michael D, Tufano
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