Results 111 to 120 of about 23,803 (294)

Molecular docking and synthesis of N-alkyl-isatin-3-imino aromatic amine derivatives and their antileishmanial and cytotoxic activities

open access: yesResearch in Pharmaceutical Sciences
Background and purpose: Isatin derivatives have excited attention due to their biological attractions, especially, anticancer properties. Isatin analogs such as semaxanib and sunitinib were exposed to tyrosine kinase inhibitory properties.
Farshid Hassanzadeh   +4 more
doaj   +1 more source

Synthesis and fluorine-mediated interactions in methanol-encapsulated solid state self-assembly of an isatin-thiazoline hybrid

open access: yes, 2015
International audienceAn exciting isatin-thiazoline hybrid molecule 2 having -C=N-N=C- linkage has been synthesized in 88% yield by the reaction of 5-fluoroisatin with N-(4-fluorophenyl)hydrazinecarbothioamide followed by condensation of the resultant ...
Ahmad, Maqbool   +4 more
core   +2 more sources

Synthesis of co(II), Ni(II) and Cu(II) complexes from schiff base ligand and reactivity studies with thermosetting epoxy resin [PDF]

open access: yes, 2011
A hybrid thermosetting maleimido epoxy compound 4-(N-maleimidophenyl) glycidylether (N-MPGE) containing Co(II), Ni(II) and Cu(II) ions was prepared by curing N-MPGE and tetradentate Schiff base Co(II), Ni(II) and Cu(II) complexes.
Lakshmi, B.   +4 more
core   +1 more source

Synthesis, characterization and biological activities of a new Isatin Schiff base and its metal complexes [PDF]

open access: yes, 2013
The complexes of Copper(II)​, Cobalt(II)​, Nickel(II) and Zinc(II) of Isatin Schiff base (L) (L = Schiff base derived from Isatin and 2-​methyl-​4-​nitroaniline) were synthesized and characterized.
Mahendra, K.N.   +2 more
core  

Thermal and structural analysis of 4,5,6-trimethoxyisatin [PDF]

open access: yes, 2009
4,5,6-Trimethoxyisatin was crystallized from water to give dark red needles that were characterized by NMR and IR spectroscopy, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), single-crystal X-ray diffraction (XRD) and hot ...
Campos, Ana M. F. Oliveira   +6 more
core   +1 more source

THE SYNTHESIS OF NEW SPIROLACTONES FROM SUBSTITUTED ISATINS [PDF]

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2015
Interaction of N-ethyl isatin 3 with dimethyl acetylenedicarboxylate in the presence triphenylphosphine has led to good selectivity of methyl 1'-ethyl-4-methoxy-2',5-dioxo-5H-spiro[furan-2,3'-indoline]-3-carboxylate 4 formation.
Natalia Sucman   +5 more
doaj  

Polar [3 + 2] cycloaddition of ketones with electrophilically activated carbonyl ylides. Synthesis of spirocyclic dioxolane indolinones.

open access: yes, 2008
International audienceThe [3 + 2] cycloaddition reaction between carbonyl ylides generated from epoxides and ketones (ethyl pyruvate, ethyl phenylglyoxylate, isatin, N-methylisatin and 5-chloroisatin) to give substituted dioxolanes and spirocyclic ...
Bentabed-Ababsa, Ghenia   +5 more
core   +3 more sources

The Potential of Quinoline Derivatives for the Treatment of Toxoplasma gondii Infection. [PDF]

open access: yes, 2014
Here we reported our investigation, as part of our drug repositioning effort, on anti-Toxoplasma properties of newly synthesized quinoline compounds. A collection of 4-aminoquinoline and 4-piperazinylquinoline analogs have recently been synthesized for ...
Ananvoranich, Sirinart
core   +2 more sources

Evaluation of the Antibacterial Activity of Isatin against Campylobacter jejuni and Campylobacter coli Strains

open access: yesApplied Microbiology
Antibiotic resistance, particularly against fluoroquinolones and macrolides, has emerged globally among thermophilic Campylobacters (Campylobacter jejuni and Campylobacter coli), giving rise to concerns about the efficacy of antibiotic treatment of these
Claudia B. Barroso   +4 more
doaj   +1 more source

Room Temperature, Open-Flask C–P Bond-Formation on Water under Catalyst-Free Conditions

open access: yesSynOpen, 2018
A catalyst-free C–P bond-formation in an open flask at room temperature between isatin derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing different substitutes underwent C–P coupling reaction with a variety of ...
Rakhee Choudhary   +4 more
doaj   +1 more source

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