Results 11 to 20 of about 23,803 (294)

Spectroscopic studies on Isatin-3-Semicarbazone and Isatin-3-Thiosemicarbazone

open access: hybridGlobal Journal of Pure and Applied Sciences, 2004
The configurations of semi-and thiosemicarbazone derivatives of isatin are assigned by means of 1H and 13C NMR Spectroscopy including NOE difference spectra, IR and electronic spectral data of these compounds are also reported and discussed. The electron impact (EI), fast atom bombardment (FAB) and negative ion chemical ionization (NICI) mass spectra ...
Narayan T. Akinchan
openalex   +5 more sources

Simple and Efficient Microwave Assisted N-Alkylation of Isatin [PDF]

open access: goldMolecules, 2008
We present herein the results of microwave promoted N-alkylations of isatin (1)with different alkyl, benzyl and functionalized alkyl halides. Reactions were carried outunder different conditions, always employing methodologies compatible with MW ...
María Mercedes Blanco   +4 more
doaj   +2 more sources

Enantioselective Solvent-Free Synthesis of 3-Alkyl-3-hydroxy-2-oxoindoles Catalyzed by Binam-Prolinamides [PDF]

open access: yesMolecules, 2015
BINAM-prolinamides are very efficient catalyst for the synthesis of non-protected and N-benzyl isatin derivatives by using an aldol reaction between ketones and isatins under solvent-free conditions.
Abraham Bañn-Caballero   +3 more
doaj   +5 more sources

Isatin as a simple, highly selective and sensitive colorimetric sensor for fluoride anion

open access: yesHeterocyclic Communications, 2020
Herein, we report the fluoride anion sensing properties of a commercially available and inexpensive organic compound, isatin, which is found to be a highly selective and sensitive sensor.
Haider Azeem   +3 more
doaj   +2 more sources

Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2022
Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently attracted a lot of attention in medicinal chemistry. Isatin, itself,
May Mohammed Jawad Al-Mudhafar   +2 more
doaj   +1 more source

Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
In this work, new isatin-based sulphonamides (6a-i, 11a-c, 12a-c) were designed and synthesised as potential dual VEGFR-2 and carbonic anhydrase inhibitors with anticancer activities.
M. Shaldam   +11 more
semanticscholar   +1 more source

Synthesis, Characterization, and Antibacterial Activity of New Isatin Derivatives

open access: yesPharmaceutical Chemistry Journal, 2023
1H-indol-2,3-dione (isatin) class of biologically active compounds have analgesic, anti-microbial, anti-inflammatory, anti-tubercular, anti-proliferative properties, and is also useful for the treatment of SARS-CoV.
S. Nain   +4 more
semanticscholar   +1 more source

Anticancer Compounds Based on Isatin-Derivatives: Strategies to Ameliorate Selectivity and Efficiency

open access: yesFrontiers in Molecular Biosciences, 2021
In this review we compare and discuss results of compounds already reported as anticancer agents based on isatin-derivatives, metalated as well as non-metallated.
Raphael Enoque Ferraz de Paiva   +4 more
semanticscholar   +1 more source

The impact of isatin derivatives on antibiotic production by Streptomyces hygroscopicus CH-7 [PDF]

open access: yesHemijska Industrija, 2016
The effect of isatin derivatives as a nitrogen source on antibiotic (Hexaene H-85 and Azalomycine B) production by Streptomyces hygroscopicus CH-7 was studied.
Ćirić Jovan T.   +5 more
doaj   +1 more source

Isatin derivatives as broad-spectrum antiviral agents: the current landscape

open access: yesMedicinal Chemistry Research, 2022
In recent decades, several viruses have resulted in large outbreaks with serious health, economic and social consequences. The current unprecedented outbreak of the new coronavirus, SARS-COV-2, necessitates intensive efforts for delivering effective ...
T. Elsaman   +6 more
semanticscholar   +1 more source

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