Results 11 to 20 of about 9,186 (209)
A Scalable and Sustainable Synthesis of Indirubin Frameworks Enabled by Deep Eutectic Solvents. [PDF]
ChemSusChemA sustainable protocol for the synthesis of indirubin in a choline chloride/urea deep eutectic solvent at 70°C under air affords the product in 70% yield without chromatography. The method is robust, scalable to pilot scale, and enables late‐stage functionalization, granting access to a wide range of indirubin derivatives. CHEM21 green metrics validate
Delvecchio B +5 more
europepmc +2 more sources
Recent Advances in Isatin-Thiazole Hybrids: Synthesis, Structural Design, and Biological Application. [PDF]
Chem BiodiversABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Andrade IMG +4 more
europepmc +2 more sources
Estimation of isatin in spiked plasma samples using high performance liquid chromatography [PDF]
Chemical Industry and Chemical Engineering Quarterly, 2013 An isocratic analytical method based on liquid chromatographic determination with UV detection is described for the determination of isatin in spiked plasma and in its synthetic mixture.
Alothman Zeid A. +2 more
doaj +1 more source
Corrosion and Inhibition of Cu-Zn Alloys in Acidic Medium by Using Isatin
International Journal of Electrochemical Science, 2008 The effect of isatin on the corrosion of Cu-Zn alloys in H2SO4 and HCl solution has been studied using open circuit potential, potentiodynamic, and electrochemical impedance spectroscopy (EIS) techniques.
S.A.M. Refaey +3 more
doaj +2 more sources
Antioxidants, 2022 Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers and is estimated to be the fifth most common cause of cancer-related death worldwide.
Nagwa G. Tawfik +6 more
doaj +1 more source
Pharmaceuticals, 2022 Isatin, chemically an indole-1H-2,3-dione, is recognised as one of the most attractive therapeutic fragments in drug design and development. The template has turned out to be exceptionally useful for developing new anticancer scaffolds, as evidenced by ...
Shefali Chowdhary +3 more
doaj +1 more source
Molecules, 2017 Five isatin anions were prepared by deprotonation of initial isatins in aprotic solvents using basic fluoride and acetate anions (F− and CH3COO−). The F− basicity is sufficient to deprotonate isatin NH hydrogen from all the studied compounds.
Pavol Tisovský +9 more
doaj +1 more source
BMC Neuroscience, 2002 Background Previous studies have demonstrated that centrally administered natriuretic peptides and pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) have hyperthermic properties.
Tóth Gábor +4 more
doaj +1 more source
The influence of Schiff base inclusion complexes with β-cyclodextrine on antibiotic production by Streptomyces hygroscopicus CH-7 [PDF]
Hemijska Industrija, 2015 A media consisting of isatin-Schiff bases and its inclusion complexes with β-cyclodextrine was developed to maximize the production of antibiotics Hexaene H-85 and Azalomycine β by Streptomyces hygroscopicus CH-7.
Ilić Slavica B. +4 more
doaj +1 more source
Design, synthesis, docking, and antidepressant activity evaluation of isatin derivatives bearing Schiff bases [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Depression is a prevalent psychiatric disorder. Treatment of depression is still a challenge due to the lack of response of some patients to a variety of available medications and side effects.
Azadeh Mesripour +3 more
doaj +1 more source