Results 21 to 30 of about 17,152 (250)
BMC Neuroscience, 2002 Background Previous studies have demonstrated that centrally administered natriuretic peptides and pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) have hyperthermic properties.
Tóth Gábor +4 more
doaj +1 more source
Carbon and Heteroatom Activation via N-Heterocyclic Carbene-Bound Dearomative Intermediates for Stereoselective Annulation Reactions. [PDF]
ChemistryUse of N‐heterocyclic carbenes (NHCs) to activate carbon and heteroatoms in aromatic compounds is reviewed based on key dearomative NHC‐bound intermediates, i.e., ortho‐quinodimethanes (o‐QDMs), ortho‐quinone methides (o‐QMs) and aza‐analogs (aza‐o‐QMs), aza‐fulvene and triaza‐diene intermediates.
De Risi C +4 more
europepmc +2 more sources
Pharmaceuticals, 2022 Isatin (1H indole 2, 3-dione) is a heterocyclic, endogenous lead molecule recognized in humans and different plants. The isatin nucleus and its derivatives are owed the attention of researchers due to their diverse pharmacological activities such as ...
Rameshwar S. Cheke +11 more
doaj +1 more source
Isatin thiosemicarbazone-blended polymer films for biomedical applications : surface morphology, characterisation and preliminary biological assessment [PDF]
, 2016 Poly (methyl methacrylate) and polyurethane are polymers currently used for a range of biomedical applications. To modify their surface characteristics, biocompatibility and potentially reduce any related side effects the addition to the polymers of ...
Alexiou, Polyxeni +5 more
core +1 more source
Life Sciences, 2016 There has been growing interest in the synthesis of new derivatives from isatin, found in Isatis genus. Our objectives were to characterize the antinociceptive mechanism of action of isatin, N-methyl-isatin (MI) and N-methyl-3-(2-oxopropyl)-3-hydroxy-2-oxindole (MOI).Substances (0.1-10mg/kg, p.o.) were studied in chemical (paw licking induced by ...
Thais Biondino Sardella Giorno +3 more
openaire +2 more sources
Isatin as a simple, highly selective and sensitive colorimetric sensor for fluoride anion
Heterocyclic Communications, 2020 Herein, we report the fluoride anion sensing properties of a commercially available and inexpensive organic compound, isatin, which is found to be a highly selective and sensitive sensor.
Haider Azeem +3 more
doaj +1 more source
Umpolung Activation of Bicyclobutanes via N-Heterocyclic Carbene Catalysis. [PDF]
Angew Chem Int Ed EnglNHC‐catalyzed umpolung of bicyclo[1.1.0]butane (BCB) aldehydes enables nucleophilic cycloaddition with carbonyls and imines to form bicyclic lactones and lactams. The resulting oxa‐ and aza‐bicyclo[3.1.1]heptane products can be further transformed into valuable rigid 3D scaffolds, offering a simple and versatile approach to access new chemical space ...
Chang YC +5 more
europepmc +2 more sources
Synthesis, Characterization and Biological Activities of a New 5-Chloroisatin Schiff Base and its Metal Complexes [PDF]
, 2013 Copper(II), cobalt(II), nickel(II) and zinc(II) complexes of 5-chloroisatin Schiff base (L) (L= Schiff base derived from 5-chloroisatin and 2-methyl-4- nitro aniline) were synthesized and characterized.
Mahendra, K.N. +2 more
core +1 more source
Bulletin of Chemical Reaction Engineering & Catalysis, 2019 An efficient and easy procedure is developed for the synthesis of isatin aldazines or bis-Schiff bases of isatin, catalyzed by a proton exchanged Algerian montmorillonite clay (MMT-H+) as green catalyst.
Boumadiene Benlahreche +3 more
doaj +1 more source
Ruthenium catalyzed oxidative conversion of isatins to anthranilic acids: Mechanistic study [PDF]
, 2008 Oxidation of isatins (isatin, 5-methylisatin, 5-bromoisatin, and 5-nitroisatin) to their corresponding anthranilic acids was performed with sodium N-bromo-p-toluenesulfonamide or bromamine-T (BAT) as an oxidant and ruthenium trichloride (Ru(III)) as a ...
Gowda, N.M.N. +3 more
core +1 more source