Results 81 to 90 of about 23,803 (294)

Isatin Endowed Metal Chelates as Antibacterial and Antifungal Agents

, 2020
River ABSTRACT A new series of 5-chloroindoline-2,3-dione (isatin) derived ligands (L1)-(L4) were prepared by reacting isatin with various diamines such as ethane-1,2-diamine, propane-1,3-diamine, butane-1,4-diamine, and benzene-1,2-diamine in an ...
S. Khalid, S. Sumrra, Z. Chohan
semanticscholar   +1 more source

Synthesis, Characterisation and Biological Activity Screening Of Schiff Base Ligands Containing Isatin and Their Metal Complexes [PDF]

, 2008
Six new Schiff bases formed from the condensation reaction of S-benzyldithiocarbazate (SBDTC) and S-methyldithiocarbazate (SMDTC) with selected diketones containing isatin derivatives namely isatin, 5-fluroisatin, 5-chloroisatin, 5-bromoisatin and ...
Abdul Manan, Mohd Abdul Fatah
core  

Síntese e caracterização estrutural do ligante isatina-3-(N4-benziltiossemicarbazona) e do seu complexo de mercúrio(II) Synthesis and structural characterization of the ligand isatin-3-(N4-benzylthiosemicarbazone) and its mercury(II) complex

Química Nova, 2010
The reaction of 4-(phenyl)thiosemicarbazide with isatin yielded a new ligand, isatin-3-(N4-benzylthiosemicarbazone). Isatin-3-(N4-benzylthiosemicarbazone) deprotonated in ethanol/KOH reacts with an ethanolic solution of Hg(NO3)2 to give a mercury complex.
Alexandra de Souza Fonseca, Gisele Louro Peres, Tomás Garcia Storino, Leandro Bresolin, Vanessa Santana Carratu, Vinícius F. Giglio, Estela dos Reis Crespan, Manfredo Hörner   +7 more
doaj   +1 more source

A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers

ChemBioChem, Volume 26, Issue 11, June 3, 2025.
This bacterial enzyme, cyclase‐phosphotriesterase (C‐PTE) from Ruegeria pomeroyi DSS‐3, shows significant potential for breaking down organophosphate pollutants. Beyond its capability to hydrolyze specific plasticizers such as triphenyl phosphate and tris(2‐chloropropyl) phosphate, C‐PTE's crystal structure reveals a binuclear zinc active site, and it ...
Dawei Ji, Rebecca L. Frkic, Javad Delyami, Joachim S. Larsen, Matthew A. Spence, Colin J. Jackson   +5 more
wiley   +1 more source

1-Benzyl-5-methylindoline-2,3-dione

IUCrData, 2016
The title compound, C16H13NO2, is an isatin (indole-2,3-dione) derivative. The isatin moiety is almost planar with an r.m.s. deviation of 0.022 Å, and its mean plane makes a dihedral angle of 74.19 (12)° with the benzyl ring.
N. Sharmila, T. V. Sundar, G. Satish, P. Venkatesan   +3 more
doaj   +1 more source

Design, synthesis and biological evaluation of thiosemicarbazones, hydrazinobenzothiazoles and arylhydrazones as anticancer agents with a potential to overcome multidrug resistance [PDF]

, 2016
There is a constant need for new therapies against multidrug resistant (MDR) cancer. An attractive strategy is to develop chelators that display significant antitumor activity in multidrug resistant cancer cell lines overexpressing the drug efflux pump P-
Füredi, András, Lovrics, Anna, Pape, Veronika F. S., Szakács, Gergely, Szebényi, Kornélia, Tóth, Szilárd   +5 more
core   +1 more source

Synthesis, Antimicrobial, and Anticancer Activities of Novel Nitrofuran Derivatives

Journal of Chemistry, 2023
Keeping in view the varying therapeutic attributes of 5-nitrofuran and isatin derivatives, novel 5-nitrofuran‒isatin molecular hybrids (2, 5–7) were synthesized by standard protocols, characterized by various spectroscopic techniques, and eventually ...
Malik Suliman Mohamed, Khaled M. Elamin, Rawaf Alenazy, Eyman Mohamed Eltayib, Mona Timan Idriss, Noura A. A. Alhudaib, Tilal Elsaman, Magdi Awadalla Mohamed   +7 more
doaj   +1 more source

ChemInform Abstract: Enantioselective Organocatalytic Reactions with Isatin.

ChemInform, 2013
[EN] Isatin and its derivatives have been widely studied due to their biological activities. Recently there has been a renewed interest in the synthesis of new derivatives by use of organocatalysts. This review deals with this area.
Flores, MariFe, Peña, Javier, García García, Pilar, Garrido, Narciso M., Diez, David   +4 more
openaire   +4 more sources

Multi‐Omics Analysis Reveals Disturbances of Purine Metabolism and Glutamate Metabolism in the Hippocampus of Lipopolysaccharide‐Induced Mouse Model of Depression

Brain and Behavior, Volume 15, Issue 5, May 2025.
The study focused on a mouse model of depression induced by lipopolysaccharides (LPS) and employed innovative multi‐omics approaches, including two‐dimensional gel electrophoresis (2‐DE) for proteomics, liquid chromatography–mass spectrometry (LC–MS) for metabolomics, and real‐time polymerase chain reaction (PCR) microarray technology to analyze the ...
Wen‐Wen Li, Rui Xiao, Xue‐Yi Chen, Jun‐Cai Pu, Jian‐Jun Chen, Hai‐Yang Wang, Lan‐Xiang Liu, Dan Li, Yang‐Dong Zhang, Wen‐Xia Li, Peng Xie   +10 more
wiley   +1 more source

Asymmetric vinylogous Mukaiyama aldol reaction of isatins under bifunctional organocatalysis: Enantioselective synthesis of substituted 3-hydroxy-2-oxindoles [PDF]

, 2018
A highly enantioselective organocatalytic vinylogous Mukaiyama aldol reaction of silyloxy dienes and isatins under bifunctional organocatalysis is presented. Substituted 3-hydroxy-2-oxindoles are synthesised in good yields and enantioselectivities. These
Alemán, José, Fernández Salas, José Antonio, Humbrías-Martín, Jorge, Laina-Martín, Víctor   +3 more
core   +2 more sources