Results 81 to 90 of about 16,503 (251)

Neurohormonok, neuropeptidek szerepe az idegrendszer és az endokrin rendszer adaptatív működésének szabályozásában = The role of neurohormones and neuropeptides in the regulation of the adaptive function of the neural and endocrine system [PDF]

, 2006
Összefoglalás A vizsgált periodusban a vállalt feladat több neuropeptidnek mint a PACAP 38, orexin A és B endomorphin-1, a MERF, apelin-13, urocortin 1 , 2 és 3, valamint a ghrelinnek vizsgálata olyan idegrendszeri funkciókban mint a tanulás és ...
Gecse, Árpád, Hargitainé Bujdosó, Erika, Jászberényi, Miklós, Kiss, Edina, Kálmánné Adamik, Ágnes, Lepránné Mezei, Zsófia, Pataki, Imre, Telegdy, Gyula, Tiricz, Hilda   +8 more
core  

Ruthenium(II)‐Arene Complexes Containing Aryl‐Isatin Schiff Bases and Their Effects on Colon Cancer Cell Lines

Applied Organometallic Chemistry, Volume 39, Issue 8, August 2025.
Aryl‐isatin Schiff base ruthenium (II)‐arene Ru1 complex has (IC50 value of 5.36 ± 1.09) a strong ability to inhibit the growth of SW620 cell line. The intrinsic binding constant Kb of the complex Ru1 was 5.14 × 106 M−1. In absorption spectral study, hyperchromism and hypsochromism were clear indicators that suggested the intercalative type of mode of ...
Aslıhan Karaer Tunçay, Yonca Gungor, Hande Karabıyık, Hulya Ayar Kayali, Hayati Türkmen   +4 more
wiley   +1 more source

Synthesis, Antimicrobial, and Anticancer Activities of Novel Nitrofuran Derivatives

Journal of Chemistry, 2023
Keeping in view the varying therapeutic attributes of 5-nitrofuran and isatin derivatives, novel 5-nitrofuran‒isatin molecular hybrids (2, 5–7) were synthesized by standard protocols, characterized by various spectroscopic techniques, and eventually ...
Malik Suliman Mohamed, Khaled M. Elamin, Rawaf Alenazy, Eyman Mohamed Eltayib, Mona Timan Idriss, Noura A. A. Alhudaib, Tilal Elsaman, Magdi Awadalla Mohamed   +7 more
doaj   +1 more source

ChemInform Abstract: Enantioselective Organocatalytic Reactions with Isatin.

ChemInform, 2013
[EN] Isatin and its derivatives have been widely studied due to their biological activities. Recently there has been a renewed interest in the synthesis of new derivatives by use of organocatalysts. This review deals with this area.
Flores, MariFe, Peña, Javier, García García, Pilar, Garrido, Narciso M., Diez, David   +4 more
openaire   +4 more sources

Highly Enantioselective Organocatalysis with Bidentate Halogen Bond Donors

Angewandte Chemie International Edition, Volume 64, Issue 30, July 21, 2025.
In a model Mukaiyama aldol reaction with unbiased substrates, high enantioselectivity was achieved with a modifiable bidentate iodine(I)‐based halogen bonding organocatalyst. The crucial role of halogen bonding was confirmed by the low performance of the corresponding hydrogen bond donor and via DFT calculations.
Julian Wolf, Meghana Poliyodath Mohanan, Raphaël Robidas, Revannath L. Sutar, Elric Engelage, Claude Y. Legault, Stefan M. Huber   +6 more
wiley   +1 more source

Condensation of Indole with Isatin over AlCl₃/Mesoporous Aluminosilicate

Indonesian Journal of Chemistry, 2015
Aluminium chloride immobilized on mesoporous aluminosilicate was investigated as catalysts in the condensation of isatin with indole. AlCl3/mesoporous aluminosilicate (AlCl3/AM) catalysts were prepared by impregnation of 1, 5, 10 and 15 wt% AlCl3 on the ...
Tri Esti Purbaningtias, Didik Prasetyoko, Hasliza Bahruji, Yusuf Muhammad Zein, Sugeng Triwahyono, Arief Fadlan, Imroatul Qoniah   +6 more
doaj   +1 more source

Design, synthesis and biological evaluation of thiosemicarbazones, hydrazinobenzothiazoles and arylhydrazones as anticancer agents with a potential to overcome multidrug resistance [PDF]

, 2016
There is a constant need for new therapies against multidrug resistant (MDR) cancer. An attractive strategy is to develop chelators that display significant antitumor activity in multidrug resistant cancer cell lines overexpressing the drug efflux pump P-
Füredi, András, Lovrics, Anna, Pape, Veronika F. S., Szakács, Gergely, Szebényi, Kornélia, Tóth, Szilárd   +5 more
core   +1 more source

Detection of Cisplatin with Boron‐Doped Diamond Thin‐Film Electrodes Using Flow Injection Analysis and Ion Exclusion Chromatography with Amperometric Detection

Electroanalysis, Volume 37, Issue 7, July 2025.
The electrooxidation of cisplatin was investigated at boron‐doped diamond (BDD) electrodes and the detection figures of merit were assessed by amperometric detection coupled to flow injection analysis (FIA) and ion exclusion chromatoraphy (IEC). In this work, we investigated the electrochemical behavior of cisplatin at boron‐doped diamond (BDD) thin ...
Aaron I. Jacobs, Alice W. Njue, Greg M. Swain   +2 more
wiley   +1 more source

Optimization of indirubin and indigo production in E.coli [PDF]

, 2015
The goal of this thesis is to determine the conditions that give the highest yield of indigo and indirubin in recombinant E.coli. This E.coli has been transformed with a P450 gene from woad, an indigo producing plant. The conditions investigated were the
Cairo, Gisela
core   +1 more source

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

ChemistryOpen, Volume 14, Issue 7, July 2025.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas, Gobind Kumar, Sanjeev Dhawan, Talent Makhanya, Parvesh Singh   +4 more
wiley   +1 more source