Results 191 to 200 of about 184,947,225 (237)

Targeting STAT3 to Modulate the Effectiveness of Cardioprotective Conditioning Strategies Against Myocardial Ischemia-Reperfusion Injury in Subjects With Diabetic Cardiomyopathy. [PDF]

J Cell Mol Med
Wang C, Tian W, Saedi S, Cui H, Liu D, Chu Q, Yang D, Xia Z.   +7 more
europepmc   +1 more source

Protective Effects of Antioxidant Medications on Limb Ischemia Reperfusion Injury

Journal of Surgical Research, 2007
N-acetylcysteine, beta-glucan, and coenzyme Q(10) were shown to have antioxidant and anti-inflammatory effects on reperfusion injury. The aim of our study was to determine and evaluate the effects of these agents on ischemia reperfusion injury of limb.Forty-four New Zealand white rabbits, all female, weighing between 2.3 to 4.2 (mean 3.8) kg, were used
Suat Doganci, Vedat Yildirim, Murat Sarğın   +2 more
exaly   +5 more sources

Ischemia/Reperfusion Injury of Porcine Limbs After Extracorporeal Perfusion

Journal of Surgical Research, 2013
Revascularization of amputated extremities after prolonged ischemia is complicated by reperfusion injury. We assessed ischemia/reperfusion (I/R) injury of porcine extremities after prolonged preservation using extracorporeal circulation (ECC).Forelimbs of 32 pigs were divided into four groups based on ischemia times: group I: 6 h, group II: 12 h, group
Jan A Plock, Robert Rieben, Hansjörg Jenni   +2 more
exaly   +5 more sources

Hind Limb Ischemia–Reperfusion Injury in Diet-Induced Obese Mice [PDF]

Journal of Surgical Research, 2014
Obesity is a major risk factor for the development of diabetes. Limb ischemia-reperfusion injury (IR) is a common clinical problem in diabetics who have compromised lower extremity perfusion. This study compared the histologic, metabolic, and functional outcomes after hind limb IR in diet-induced obese (DIO) and non-diabetic (ND) mice during the acute ...
Hassan Albadawi, Rahmi Oklu, Michael T Watkins   +2 more
exaly   +3 more sources

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Mortality Following Lower Limb Ischemia-Reperfusion: A Systemic Inflammatory Response?

World Journal of Surgery, 1996
AbstractRestoration of blood flow to an acutely ischemic lower limb may paradoxically result in systemic complications and unexpected mortality. It has been suggested that lower limb ischemia reperfusion alters gut permeability. In this study, using a rat model, we determined the effect of acute lower limb ischemia‐reperfusion on mortality rate, bowel ...
Brian J Rowlands, A A Barros D'Sa, B J Rowlands   +2 more
exaly   +3 more sources