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The Effects of Erdosteine on Lung Injury Induced by the Ischemia-Reperfusion of the Hind-Limbs in Rats

Journal of Surgical Research, 2008
[corrected] The goal of this experimental study was to investigate whether erdosteine has a protective effect against lung injury as a remote organ after hind-limb ischemia-reperfusion (I/R).The rats were divided into three groups: control, I/R, and I/R + erdosteine.
Yilmaz, H. Ramazan   +7 more
openaire   +4 more sources

Ischemia: reperfusion syndrome of the lower limbs.

International angiology : a journal of the International Union of Angiology, 1997
The ischemia-reperfusion syndrome, first described by Haimovici in 1960, is a severe complication following surgery for acute ischemia. We evaluated the incidence of this complication in 264 patients operated on between 1972 and 1981 (1st group) and compared it with another of 392 patients operated on between 1982 and 1991 (2nd group), our aim being to
F, Magnoni   +4 more
openaire   +1 more source

Apocynin and dimethyl sulfoxide synergistically protect against ischemia-reperfusion injury in a rat hind limb ischemia-reperfusion model

European Journal of Plastic Surgery, 2017
Acute ischemia and reperfusion in extremities ignite a complicated inflammatory cycle and lead to damage in the extremities and target tissues. Rats were randomly divided into four groups. Each experimental group contained eight rats. Group 1 was the sham surgery group.
Alpay Duran   +7 more
openaire   +2 more sources

Structural and Functional Disorders of Hippocampus Following Ischemia/Reperfusion in Lower Limbs and Kidneys

Neuroscience, 2017
Recent evidence suggests that ischemia/reperfusion (I/R) in an organ may have distance effect on the brain. In this study, the effects of renal I/R, limb I/R or both together on the structural and function of hippocampus were evaluated and compared. Hence, rats were subjected to 2-h bilateral lower limb ischemia, 45-min bilateral renal ischemia, or ...
Seyed Moosavi   +2 more
exaly   +3 more sources

Macromolecules reduce abnormal microvascular permeability in rat limb ischemia-reperfusion injury

Critical Care Medicine, 1989
We studied the effect of iv administration of biodegradable macromolecules on microvascular permeability after ischemia-reperfusion injury in a rat gastrocnemius model. After 2 h of tourniquet ischemia of the rats' hind limb, groups of animals were given iv lactated Ringer's solution (RL), serum albumin 5%, or varying MW fractions of biodegradable ...
B A, Zikria   +7 more
openaire   +2 more sources

Collateral circulation of the rat lower limb and its significance in ischemia–reperfusion studies

Surgery Today, 2013
Rats are the most commonly used animal model for studies of acute lower limb ischemia-reperfusion. The ischemia induced by arterial clamping may cause milder damage than the application of a tourniquet if the presence of a possible collateral system is considered.Male Wistar rats were randomized into three groups: in group A, the muscle weight affected
Rosero, Olivér   +11 more
openaire   +3 more sources

Heparin attenuates HMGB1 expression in arterial tissue subjected to limb ischemia/reperfusion

International Journal of Cardiology, 2014
limb ischemia/reperfusion Yang Liu , Yuxiang He , Xuejun Wu , Shiyi Zhang , Zhenyue Chong , Yue Jiang , Changyou Zhou , Xing Jin a,⁎,1 a Department of Vascular Surgery, Shandong Provincial Hospital affiliated to Shandong University, No. 324, Road Jing Wu Wei Qi, Jinan 250021, Shandong, China b Department of Vascular Surgery, Shandong Provincial ...
Yang, Liu   +7 more
openaire   +2 more sources

Hind Limb Ischemia-Reperfusion in the Leptin Receptor Deficient (db/db) Mouse

Journal of Surgical Research, 2007
Diabetic patients have high incidence of peripheral vascular disease and limb loss after acute extremity injury. Experiments were designed to test the hypothesis that acute tissue injury in leptin receptor deficient (Db) diabetic (type2) mice would be more severe than in non-diabetic mice.Db and wild type (Wt) mice were subjected to 3 h of ischemia ...
Fateh, Entabi   +5 more
openaire   +2 more sources

[Effects of rabbit limbs ischemia/ reperfusion on myocardial necrosis and apoptosis].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2014
To investigate the effects of rabbit limbs ischemia/reperfusion on myocardial necrosis and apoptosis in vivo.Thirty-six healthy new zealand rabbits were randomly divided into 3 groups: (1) Sham group; (2) I/R(Ischemia/reperfusion) group; (3) RPostC (remote postconditioning) group.
Hui-Min, Ren   +5 more
openaire   +1 more source

[The importance of hemorheological examinations in experimental limb ischemia-reperfusion injuries].

Magyar sebeszet, 2005
Rheological properties of the blood are determined by several factors and if they change it may be diagnostic for many diseases. It is well-known that during ischemia and reperfusion different free-radical liberating pathways are inducted besides the local physical and metabolical changes.
Norbert, Németh   +10 more
openaire   +1 more source

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