Results 151 to 160 of about 6,150 (181)
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Natural Polyphenols as Modulators of the Fibrillization of Islet Amyloid Polypeptide
2020Diabetes mellitus type 2 (type-2 diabetes) is a metabolic disorder characterized by the increased blood glucose concentration and insulin resistance in peripheral tissues (e.g., muscles and adipose tissue). The initiation of the pathological cascade of events that lead to type-2 diabetes has been subject of debate; however, it has been commonly ...
Araújo, Ana R. +2 more
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Islet Amyloid Polypeptide: Synthetic Peptides for Study of the Pathogenesis of Islet Amyloid
1991Studies have indicated that the 20-29 segment of islet amyloid polypeptide (IAPP) determines the fibril formation. Variations between species in this region explain why only some species develop islet amyloid. This assumption is strongly supported by our study where we have used synthetic peptides in an fibril formation test system.
Per Westermark +6 more
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Formation of islet amyloid from islet amyloid polypeptide
Biochemical Society Transactions, 1993A, Clark, E J, de Koning, J F, Morris
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Islet-amyloid polypeptide in human plasma
The Lancet, 1990Van Jaarsveld, B. C. +5 more
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The role of SORLA in islet amyloid polypeptide transport and islet amyloid deposition
Der Sorting Related Receptor with A-type Repeats (SORLA) ist ein Sortierrezeptor, der von SORL1 kodiert wird, einem der Hauptrisikogene für die sporadische Alzheimer-Krankheit (AD). SORLA schützt vor Alzheimer, indem es die Akkumulation von Amyloid-beta-Peptiden in Amyloid-Plaque-Ablagerungen im Gehirn verhindert.openaire +1 more source
Altered islet amyloid polypeptide (amylin) gene expression in rat models of diabetes
Diabetologia, 1989S I Girgis, D Bretherton-Watt, Legon S
exaly