Results 71 to 80 of about 39,685 (253)

The Essentiality of Amino Acids in Healthiness and Disease State: Type II Diabetes as a Case Study

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
This review investigates the functions of amino acids in normal physiological states, their potential as a diagnostic biomarker, the probable risk of deficiency, and the therapeutic ability for managing and preventing type 2 diabetes mellitus. ABSTRACT A healthy life depends on the availability and the synthesis of amino acids as they are building ...
Samuel Idowu Fayomi, Ochuko Lucky Erukainure, Nontokozo Zimbili Msomi   +2 more
wiley   +1 more source

Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans [PDF]

, 2019
Introduction: Decellularization of pancreata and repopulation of these non-immunogenic matrices with islets and endothelial cells could provide transplantable, endocrine Neo-Pancreata.
Napierala, Hendrik
core   +1 more source

HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13. [PDF]

PLoS ONE, 2012
We have previously performed a genome-wide linkage study in Scandinavian Type 1 diabetes (T1D) families. In the Swedish families, we detected suggestive linkage (LOD≤2.2) to the chromosome 5p13-q13 region.
Samina Asad, Pernilla Nikamo, Alexandra Gyllenberg, Hedvig Bennet, Ola Hansson, Nils Wierup, Diabetes Incidence in Sweden Study Group, Annelie Carlsson, Gun Forsander, Sten-Anders Ivarsson, Helena Larsson, Åke Lernmark, Bengt Lindblad, Johnny Ludvigsson, Claude Marcus, Kjersti S Rønningen, Jan Nerup, Flemming Pociot, Holger Luthman, Malin Fex, Ingrid Kockum   +20 more
doaj   +1 more source

Congenital absence of islets of Langerhans. [PDF]

Archives of Disease in Childhood, 1977
A small-for-dates male infant who developed acute metabolic acidosis shortly after birth had diabetes and died aged 40 hours. At necropsy there was an absence of any recognizable islets of Langerhans though lymphorecticular aggregates were found. This was the fourth child of healthy unrelated parents whose first child, also a male, died at 48 hours ...
J A Dodge, K M Laurence
openaire   +3 more sources

Assessment of Diabetes Mellitus Retrieving Potential of Low Caloric Jamun (Syzygium cumini) Drink Through Animal Modeling

Food Science &Nutrition, Volume 13, Issue 5, May 2025.
Effect of low caloric Jamun drink on Streptozotocin‐induced diabetes in Sprague Dawley rats. ABSTRACT Diabetes mellitus, a metabolic disorder characterized by persistent hyperglycemia, impacts millions worldwide. Although Syzygium cumini L. (Jamun) has been traditionally utilized for its antidiabetic properties, its efficacy remains underexplored. This
Huma Saeed, M. Asim Shabbir, Ahmad Rafi, Ahmad Din, Moazzam Rafiq Khan, Poonam Gill, Muhammad Afzaal, Faiyaz Ahmed, Md Faruque Ahmad, Noor Akram, Gebremichael Gebremedhin Hailu   +10 more
wiley   +1 more source

Pancreas and islet cell transplantation [PDF]

, 2002
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use of exogenous insulin can be achieved only with pancreas or islet cell transplantation.
A.N. Balamurugan, Alexander, Allen, Amos, Barber, Barrou, Bartlett, Björk, Bonner-Weir, Brekke, Calne, Calne, Cameron, Cheung, Chow, Corry, Diem, Diem, DiLandro, Fontes, Giannoukakis, Giannoukakis, Gibson, Gliedman, Grey, Groth, Groth, Gu, Gupta, Harris, Hayek, Henry, Ilieva, Kelly, Kemp, Kendall, Kendall, Keymeulen, Kirk, Koike, Koike, Lacy, Lafferty, Lakey, Lillehei, London, Massimo Trucco, Mazariegos, Mintz, Murray, Najarian, Nghiem, Paraskevas, Petruzzo, Piehlmeier, Pipeleers-Marichal, Posselt, Prevost, Rajotte, Ramiya, Ramos, Ricordi, Rita Bottino, Robertson, Shapiro, Simeonovic, Solders, Sollinger, Sollinger, Sollinger, Soria, Ssobolew, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stone, Stratta, Stratta, Sutherland, Suzuki, Tchervenivanov, Terasaki, Thomas E. Starzl, Tyden, Tzakis, Yasunami   +94 more
core   +1 more source

Antihyperglycemic and Antioxidative Stress Effects of Erythrophleum africanum (Fabaceae) Trunk Bark Powder Fractions on High‐Calorie Diet‐Induced Type 2 Diabetes in Rats

Food Science &Nutrition, Volume 13, Issue 5, May 2025.
The powder fraction of Erythrophleum africanum with a size less than 50 μm prevents the occurrence of type 2 diabetes induced by the combination of a high‐calorie diet and the intake of dexamethasone. E. africanum has antihyperglycemic and antioxidative stress effects and improves the lipid profile by reducing the atherogenic index. This plant would be
Mathieu Sini, Faustin Dongmo, Clemence Mvongo, Michel Archange Fokam Tagne, Pierre Jidibe, Angèle Foyet Fondjo, Paul Aimé Noubissi, René Kamgang   +7 more
wiley   +1 more source

Development of the Islets of Langerhans in Man [PDF]

Nature, 1961
VERY little has been published about the differentiation of the α and β cells in the development of the pancreatic islets in man. The only work since the introduction of the modern granule stains is that of Ferner and Stoeckenius1 (based on twelve fœtal pancreases), and Schultze Jena2 (based on six ...
openaire   +3 more sources

The Anti‐Inflammatory Effects of Liraglutide in Equine Inflammatory Joint Models

Journal of Orthopaedic Research, Volume 43, Issue 5, Page 893-903, May 2025.
ABSTRACT This study investigates the anti‐inflammatory properties of liraglutide, a glucagon‐like peptide 1 receptor agonists, in equine in vitro models and in an in vivo acute synovitis model in Shetland ponies. The anti‐inflammatory effect of liraglutide was assessed by measuring concentrations of inflammatory biomarker C‐C Motif Chemokine Ligand 2 ...
Ann‐Sofie Scheike, Saskia Plomp, Maria Carlotta Fugazzola, Coralie Meurot, Francis Berenbaum, Paul René van Weeren, Marianna Andriana Tryfonidou, Johannes Hendrick von Hegedus   +7 more
wiley   +1 more source

How Noise and Coupling Induce Bursting Action Potentials in Pancreatic beta-cells [PDF]

, 2005
Unlike isolated beta-cells, which usually produce continuous spikes or fast and irregular bursts, electrically coupled beta-cells are apt to exhibit robust bursting action potentials.
Aguirre, Andreu, Ashcroft, Batrouni, Bosco, Chay, Chay, de Vries, de Vries, de Vries, Dean, DeFelice, Duk-Su Koh, Falke, Fox, Fox, Göpel, Halban, Henquin, Hodgkin, Hyuk Kang, Junghyo Jo, Kanno, Keener, Keizer, Kinard, Kloeden, Lee, Longtin, Moo Young Choi, Moriyama, Nadal, Pedersen, Pei, Pikovsky, Pipeleers, Pérez-Armendariz, Rinzel, Rorsman, Rulkov, Rulkov, Sherman, Sherman, Sherman, Sherman, Smith, Smolen, Sánchez-Andrés, Valdeolmillos, Zaikin   +49 more
core   +3 more sources