ABSTRACT Background Glutamate and glutamine are critical metabolites in gliomas, each serving distinct roles in tumor biology. Separate quantification of these metabolites using in vivo MR spectroscopy (MRS) at clinical field strengths (≤ 3T) is hindered by their molecular similarity, resulting in overlapping, hence indistinguishable, spectral peaks ...
Seyma Alcicek+10 more
wiley +1 more source
Venous thromboembolism incidence shortens survival in isocitrate dehydrogenase wild-type glioblastoma. [PDF]
Sloan AR+7 more
europepmc +1 more source
Differential expression in Escherichia coli of the Vibrio sp. strain ABE-1 icdI and icdII genes encoding structurally different isocitrate dehydrogenase isozymes [PDF]
Masaki Suzuki+4 more
openalex +1 more source
Mitochondrial Dysfunction in Neurodegenerative Diseases
Overview of mitochondrial dysfunction in neurodegenerative diseases (NDDs). Mitochondrial dysfunction in NDDs involves impaired ATP synthesis, Ca2+ imbalance, oxidative stress, and apoptosis. Assessment methods integrate functional assays, omics, and imaging.
Chongyang Chen+10 more
wiley +1 more source
Prognostic Biomarkers in Isocitrate Dehydrogenase Wild-Type Glioblastoma: A Focus on B7-H3. [PDF]
Yüceer RO+5 more
europepmc +1 more source
Escherichia coli Isocitrate Dehydrogenase Kinase/Phosphatase [PDF]
Katrin Rittinger+7 more
openalex +1 more source
Analysis of IDH1 and IDH2 mutations as causes of the hypermethylator phenotype in colorectal cancer
Abstract The CpG island methylator phenotype (CIMP) occurs in many colorectal cancers (CRCs). CIMP is closely associated with global hypermethylation and tends to occur in proximal tumours with microsatellite instability (MSI), but its origins have been obscure.
Joseph C Ward+59 more
wiley +1 more source
The apicoplast localized isocitrate dehydrogenase is needed for <i>de novo</i> fatty acid synthesis in the apicoplast of <i>Toxoplasma gondii</i>. [PDF]
Pan K+6 more
europepmc +1 more source
Re-evaluation of molecular weight of pig heart NAD-specific isocitrate dehydrogenase.
Robert S. Ehrlich+3 more
openalex +1 more source
Molecular cloning of an immunogenic and acid-induced isocitrate dehydrogenase gene fromCoxiella burnetii [PDF]
Sa Van Nguyen+4 more
openalex +1 more source