Results 11 to 20 of about 17,063 (164)
Synthesis, Characterization and Chemistry of Tetrakis(Propargylisocyanide) Copper(I) Complex
Molbank, 2023 The kinetically unstable propargylisocyanide was reacted with the tetrakis(acetonitrile) copper(I) hexafluorophosphate and the formed complex was then involved in a copper-catalyzed alkyne-azide cycloaddition reaction (CuAAC). After the decomplexation of
Alexandre Quelhas +3 more
doaj +1 more source
Turn-Induction in Peptides Incorporating Novel Cyrene-Derived α,α-Disubstituted Amino Acid. [PDF]
J Pept SciNovel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Bhowal KB, Hitti R, Lubell WD.
europepmc +2 more sources
Nature Communications, 2023 Abstract The S N 2 nucleophilic substitution reaction is a vital organic transformation used for drug and natural product synthesis. Nucleophiles like cyanide, oxygen, nitrogen, sulfur, or phosphorous replace halogens or sulfonyl esters, forming new bonds.
Patil, Pravin +3 more
openaire +4 more sources
Molecules, 2023 Four couples of 5,6-membered bis(metallacyclic) Pt(II) complexes with acetylide and isocyanide auxiliary ligands have been prepared and characterized.
Jing Jing +7 more
doaj +1 more source
Isocyanides: Promising Functionalities in Bioorthogonal Labeling of Biomolecules
Frontiers in Chemistry, 2021 Isocyanides have drawn increasing attention in biological applications due to their attractive properties and unique reactivities, which can undergo various reactions, such as multicomponent reactions, α-addition reactions, [4 + 1] cycloaddition ...
Yuchen Zhu +6 more
doaj +1 more source
Divergent isoindolinone synthesis through palladium-catalyzed isocyanide bridging C–H activation
Cell Reports Physical Science, 2022 Summary: The formation of thermodynamically accessible metallacycle is crucial to achieve site-selective C–H bond activation. Here, we report an isocyanide-bridging C–H activation through the formation of a five-membered palladacycle. As such, a proximal
Fulin Zhang +6 more
doaj +1 more source
Journal of Fungi, 2022 As the recent outbreak of coronavirus disease 2019 (COVID-19) has shown, viral infections are prone to secondary complications like invasive aspergillosis with a high mortality rate, and therefore the development of novel, effective antifungals is of ...
Zsuzsa Máthéné Szigeti +8 more
doaj +1 more source
Green Chemistry, 2020 Isocyanides are important chemicals, with limited availability, thus reducing their general use. Our highly improved isocyanide synthesis performed on mole to μ-mole scale, individually or in a 96-well parallel fashion enables unprecedented exploration of novel chemistries.
Pravin Patil +2 more
openaire +3 more sources
2,6-Dibromo-4-chlorophenyl isocyanide
IUCrData, 2018 Molecules of the title compound, C7H2Br2ClN (RNC), are bisected by a mirror plane that passes through the chloro and isocyano groups. The isocyano C atom is bisected by two NC...Br contacts, one per Br atom.
Wayland E. Noland, Kenneth J. Tritch
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2023 Irradiation of a toluene solution containing cyclopentadienone tricarbonyl iron complexes and isocyanides with blue LEDs afforded the formation and isolation of 12 triisocyanide complexes, two of which, namely tris(2,6-dimethylphenyl isocyanide)(η4 ...
André Bütikofer, Peter Chen
doaj +1 more source