Efficient one-pot, four-component synthesis of N,N-dibenzyl-N-{1-[5-(3-aryl)-1,3,4-oxadiazol-2-yl]cyclobutyl}amine derivatives from the reaction of (isocyanoimino)triphenylphosphorane, dibenzylamine, an aromatic carboxylic acid and cyclobutanone [PDF]
Four-component reaction of cyclobutanone, dibenzylamine and (Nisocyanimino) triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and under neutral conditions to afford N,N-dibenzyl-N-{1-[5-(3-aryl)-1,3,
Shajari Nahid +2 more
doaj +1 more source
A series of platinum complexes featuring phosphine and isocyanide ligands [PtX2(PPh3)(CNCy)] (X = Cl, Br, and I) as well as their parent phosphine [PtX2(PPh3)2] and isocyanide [PtX2(CNCy)2] analogues have been prepared and evaluated as catalysts for the ...
Maria V. Kashina +4 more
doaj +1 more source
The ALMA-PILS survey: first detection of methyl isocyanide (CH3NC) in a solar-type protostar [PDF]
International audienceMethyl isocyanide (CH3NC) is the isocyanide with the largest number of atoms confirmed in the interstellar medium (ISM), but it is not an abundant molecule, having only been detected towards a handful of objects.
Kristensen, L. E. +50 more
core +1 more source
Peptidomimetics with a substituted imidazo[1,2-a]pyridine fragment were synthesized by a tandem of Groebke–Blackburn–Bienaymé and Ugi reactions. The target products contain substituted imidazo[1,2-a]pyridine and peptidomimetic moieties as pharmacophores ...
Oleksandr V. Kolomiiets +5 more
doaj +1 more source
Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka +10 more
wiley +2 more sources
An NHC‐Coordinated Silicon/Sulfur Analogue of an Acyl Carbene
An NHC complex of an Si/S analogue of an acyl carbene is synthesized by the reaction of a disilyne with a cyclic thiourea. The observed Si2S three‐membered ring with unsymmetrical Si─S distances and a Si─Si single bond is consistent with intramolecular coordination of the silathioacyl sulfur to the silylene center.
Takuto Toyooka +2 more
wiley +2 more sources
The Chemistry of Phenylimidotechnetium(V) Complexes with Isocyanides: Steric and Electronic Factors
Organometallic approaches are of ongoing interest for the development of novel functional 99mTc radiopharmaceuticals, while the basic organotechnetium chemistry seems frequently to be little explored. Thus, structural and reactivity studies with the long-
Guilhem Claude +5 more
doaj +1 more source
Alkyl Isocyanide-Derivatized Platinum Nanoparticles [PDF]
Alkyl Isocyanide-Derivatized Platinum ...
Sarah L. Horswell (1295082) +3 more
core +1 more source
On the reaction of diphenylketene with isocyanides
The products obtained from the reaction of diphenylketene with a variety of isocyanides are shown to depend heavily on the concentration of diphenylketene; a high concentration results in the precedented dioxolane derivatives, at much lower concentrations the reactions follow an alternative course and polycyclic beta-lactams are generated by a cascade ...
Robertson, J, Bell, S, Krivokapic, A
openaire +3 more sources
Isocyanide insertion into Au-H bonds: First gold iminoformyl complexes [PDF]
Isocyanides insert into gold(III)–hydrogen bonds to give the first examples of gold iminoformyl complexes. The reaction is initiated by catalytic amounts of radicals; DFT calculations indicate that this is an equilibrium reaction driven forward by ...
Fernández Cestau, Julio +15 more
core +1 more source

