Results 31 to 40 of about 22,422 (224)
Beilstein Journal of Organic Chemistry, 2023 Peptidomimetics with a substituted imidazo[1,2-a]pyridine fragment were synthesized by a tandem of Groebke–Blackburn–Bienaymé and Ugi reactions. The target products contain substituted imidazo[1,2-a]pyridine and peptidomimetic moieties as pharmacophores ...
Oleksandr V. Kolomiiets +5 more
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The Chemistry of Phenylimidotechnetium(V) Complexes with Isocyanides: Steric and Electronic Factors
Molecules, 2022 Organometallic approaches are of ongoing interest for the development of novel functional 99mTc radiopharmaceuticals, while the basic organotechnetium chemistry seems frequently to be little explored. Thus, structural and reactivity studies with the long-
Guilhem Claude +5 more
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On the reaction of diphenylketene with isocyanides
Organic & Biomolecular Chemistry, 2005 The products obtained from the reaction of diphenylketene with a variety of isocyanides are shown to depend heavily on the concentration of diphenylketene; a high concentration results in the precedented dioxolane derivatives, at much lower concentrations the reactions follow an alternative course and polycyclic beta-lactams are generated by a cascade ...
Robertson, J, Bell, S, Krivokapic, A
openaire +3 more sources
Mixed-Isocyanide Complexes of Technetium under Steric and Electronic Control
, 2022 Reactions of the alkyl isocyanide fac-[Tc(CO)3(CNR)2Cl] complexes (2) (CNR = CNnBu or CNtBu) with the sterically encumbered isocyanide CNp-FArDarF2 [DArF = 3,5-(CF3)2C6H3] allow a selective exchange of the carbonyl ligands of 2 and the isolation of the ...
Adelheid Hagenbach (1803811) +7 more
core +1 more source
Isocyanide insertion into Au-H bonds: First gold iminoformyl complexes [PDF]
, 2018 Isocyanides insert into gold(III)–hydrogen bonds to give the first examples of gold iminoformyl complexes. The reaction is initiated by catalytic amounts of radicals; DFT calculations indicate that this is an equilibrium reaction driven forward by ...
Fernández Cestau, Julio +15 more
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Isocyanide-Based Multicomponent Reactions for the Synthesis of Heterocycles
Molecules, 2015 Multicomponent reactions (MCRs) are extremely popular owing to their facile execution, high atom-efficiency and the high diversity of products. MCRs can be used to access various heterocycles and highly functionalized scaffolds, and thus have been ...
András Váradi +3 more
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Molecules, 2017 A facile access to polysubstituted 3-(isoxazol-5-yl)pyrroles was developed through [3+2] cycloaddition of tosylmethyl isocyanide (TosMIC) and styrylisoxazoles.
Xueming Zhang, Xianxiu Xu, Dawei Zhang
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Molecules, 2023 α-Ketoamide moieties, as privileged units, may represent a valuable option to develop compounds with favorable biological activities, such as low toxicity, promising PK and drug-like properties.
Jia Xu +6 more
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, 2016 A three-component bicyclization reaction of isocyanide, substituted allenoate, and isatin has been disclosed. This protocol is proposed to proceed through Michael addition, double cyclization, and [1,5]-hydride shift sequence, thus leading to the ...
Ruolan Jiang (3137292) +7 more
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From Isocyanides to Iminonitriles via Silver-mediated Sequential Insertion of C(sp3)–H Bond
iScience, 2019 Summary: Heterocycles are prevalent constituents of many marketing drugs and biologically active molecules to meet modern medical challenges. Isocyanide insertion into C(sp3)–H bonds is challenging especially for the construction of quaternary carbon ...
Huiwen Chi +7 more
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